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页码: 182/1026 每页显示数量

Influence of Electrolyte Concentration on Single-Molecule Sensing of Perfluorocarboxylic Acids

Authors: Xinyun Yao, Ning-Ning Song, Jia Wang, Xian Zhao, Meng-Yuan Cheng, Jiaqi Zuo, Kaipei Qiu

Journal: Front Chem

PubMed ID: 34414165

Doi: 10.3389/fchem.2021.732378

Products & Services: Proteins, Expression, Isolation and Analysis

Deficient inflammasome activation permits an exaggerated asthma phenotype in rhinovirus C-infected immature mice

Authors: Mingyuan Han, Tomoko Ishikawa, Claudia C Stroupe, Haley A Breckenridge, J Kelley Bentley, Marc B Hershenson

Journal: Mucosal Immunol

PubMed ID: 34354243

Doi: 10.1038/s41385-021-00436-0

Products & Services: Mammalian Expression

Selective Neutral pH Inhibitor of Cathepsin B Designed Based on Cleavage Preferences at Cytosolic and Lysosomal pH Conditions

Authors: Michael C Yoon, Angelo Solania, Zhenze Jiang, Mitchell P Christy, Sonia Podvin, Charles Mosier, Christopher B Lietz, Gen Ito, William H Gerwick, Dennis W Wolan, Gregory Hook, Anthony J O'Donoghue, Vivian Hook

Journal: ACS Chem Biol

PubMed ID: 34416110

Doi: 10.1021/acschembio.1c00138

Products & Services: Catalog Peptides

Engineered basic fibroblast growth factor-overexpressing human umbilical cord-derived mesenchymal stem cells improve the proliferation and neuronal differentiation of endogenous neural stem cells and functional recovery of spinal cord injury by activating the PI3K-Akt-GSK-3β signaling pathway

Authors: Feifei Huang, Tianyun Gao, Wenqing Wang, Liudi Wang, Yuanyuan Xie, Chenxun Tai, Shuo Liu, Yi Cui, Bin Wang

Journal: Stem Cell Res Ther

PubMed ID: 34419172

Doi: 10.1186/s13287-021-02537-w

Products & Services: DNA Sequencing

Proteome-Wide Profiling of Readers for DNA Modification

Authors: Lin Bai, Guojian Yang, Zhaoyu Qin, Jiacheng Lyu, Yunzhi Wang, Jinwen Feng, Mingwei Liu, Tongqing Gong, Xianju Li, Zhengyang Li, Jixi Li, Jun Qin, Wenjun Yang, Chen Ding

Journal: Adv Sci (Weinh)

PubMed ID: 34351703

Doi: 10.1002/advs.202101426

Products & Services: Custom DNA/RNA Oligos

Genome-Wide Characterization and Expression Analysis Provide Basis to the Biological Function of Cotton FBA Genes

Authors: Zhong-Qing Li, Yao Zhang, He Li, Ting-Ting Su, Cheng-Gong Liu, Zi-Chao Han, Ai-Ying Wang, Jian-Bo Zhu

Journal: Front Plant Sci

PubMed ID: 34490001

Doi: 10.3389/fpls.2021.696698

Products & Services: Protein Tools

Paralogous synthetic lethality underlies genetic dependencies of the cancer-mutated gene

Authors: Melanie L Bailey, David Tieu, Andrea Habsid, Amy Hin Yan Tong, Katherine Chan, Jason Moffat, Philip Hieter

Journal: Life Sci Alliance

PubMed ID: 34462321

Doi: 10.26508/lsa.202101083

Products & Services: DNA Sequencing

Host Poly(A) Polymerases PAPD5 and PAPD7 Provide Two Layers of Protection That Ensure the Integrity and Stability of Hepatitis B Virus RNA

Authors: Fei Liu, Amy C H Lee, Fang Guo, Andrew S Kondratowicz, Holly M Micolochick Steuer, Angela Miller, Lauren D Bailey, Xiaohe Wang, Shuai Chen, Steven G Kultgen, Andrea Cuconati, Andrew G Cole, Dimitar Gotchev, Bruce D Dorsey, Rene Rijnbrand, Angela M Lam, Michael J Sofia, Min Gao

Journal: J Virol

PubMed ID: 34191584

Doi: 10.1128/JVI.00574-21

Products & Services: Gene Synthesis

Design of Broadly Cross-Reactive M Protein-Based Group A Streptococcal Vaccines

Authors: Michelle P Aranha, Thomas A Penfound, Sanaz Salehi, Anne Botteaux, Pierre Smeesters, James B Dale, Jeremy C Smith

Journal: J Immunol

PubMed ID: 34341168

Doi: 10.4049/jimmunol.2100286

Products & Services: Gene Synthesis

-Specific T Cell Functional, Memory, and Activation Profiles in QuantiFERON-Reverters Are Consistent With Controlled Infection

Authors: Cheleka A M Mpande, Pia Steigler, Tessa Lloyd, Virginie Rozot, Boitumelo Mosito, Constance Schreuder, Timothy D Reid, Nicole Bilek, Morten Ruhwald, Jason R Andrews, Mark Hatherill, Francesca Little, Thomas J Scriba, Elisa Nemes

Journal: Front Immunol

PubMed ID: 34526988

Doi: 10.3389/fimmu.2021.712480

Products & Services: Catalog Antibody

Longitudinal Follow-up of Antibody Responses in Pediatric Patients With COVID-19 up to 9 Months After Infection

Authors: Pembe Derin Oygar, Yasemin Ozsurekci, Sibel Lacinel Gurlevik, Kubra Aykac, Musa Gurel Kukul, Burcu Ceylan Cura Yayla, Sare Ilbay, Jale Karakaya, Ozlem Teksam, Ali Bulent Cengiz, Mehmet Ceyhan

Journal: Pediatr Infect Dis J

PubMed ID: 34250968

Doi: 10.1097/INF.0000000000003199

Products & Services: Proteins, Expression, Isolation and Analysis

Synthesis of precision antibody conjugates using proximity-induced chemistry

Authors: Yu J Cao, Chenfei Yu, Kuan-Lin Wu, Xuechun Wang, Dong Liu, Zeru Tian, Lijun Zhao, Xuexiu Qi, Axel Loredo, Anna Chung, Han Xiao

Journal: Theranostics

PubMed ID: 34522229

Doi: 10.7150/thno.62444

Products & Services: Recombinant Proteins

Wolf-Hirschhorn syndrome candidate 1 facilitates alveolar macrophage pyroptosis in sepsis-induced acute lung injury through NEK7-mediated NLRP3 inflammasome activation

Authors: Caixia Liu, Benlong Cai, Dan Li, Yuan Yao

Journal: Innate Immun

PubMed ID: 34428935

Doi: 10.1177/17534259211035426

Products & Services: Custom Vector Construction

Influence of in vitro neuronal membranes on the anti-amyloidogenic activity of gallic acid: Implication for the therapy of Alzheimer's disease

Authors: Stéphanie Andrade, Joana Angélica Loureiro, Maria do Carmo Pereira

Journal: Arch Biochem Biophys

PubMed ID: 34461085

Doi: 10.1016/j.abb.2021.109022

Products & Services: Mammalian Expression

Evidence of neutralizing antibodies against SARS-CoV-2 in domestic cats living with owners with a history of COVID-19 in Lima - Peru

Authors: Luis M Jara, Cusi Ferradas, Francesca Schiaffino, Camila Sánchez-Carrión, Ana Martínez-Vela, Alexandra Ulloa, Gisela Isasi-Rivas, Angela Montalván, Luis Guevara Sarmiento, Manolo Fernández, Mirko Zimic

Journal: One Health

PubMed ID: 34462726

Doi: 10.1016/j.onehlt.2021.100318

Products & Services: Proteins, Expression, Isolation and Analysis

Activation of gene expression by detergent-like protein domains

Authors: Bradley K Broyles, Andrew T Gutierrez, Theodore P Maris, Daniel A Coil, Thomas M Wagner, Xiao Wang, Daisuke Kihara, Caleb A Class, Alexandre M Erkine

Journal: iScience

PubMed ID: 34522860

Doi: 10.1016/j.isci.2021.103017

Products & Services: Molecular Biology Reagents

A novel fluorescent aptasensor based on exonuclease-assisted triple recycling amplification for sensitive and label-free detection of aflatoxin B1

Authors: Hao Wu, Hongyong Wang, Jun Wu, Guoqing Han, Yaling Liu, Pei Zou

Journal: J Hazard Mater.

PubMed ID: 33743380

Doi: 10.1016/j.jhazmat.2021.125584

Products & Services: Custom DNA/RNA Oligos

Cancer-associated fibroblasts-derived exosomal miR-3656 promotes the development and progression of esophageal squamous cell carcinoma via the ACAP2/PI3K-AKT signaling pathway

Authors: Yuan Jin, Qilin Meng, Bihui Zhang, Chen Xie, Xue Chen, Baoqing Tian, Jiakang Wang, Tsung-Chieh Shih, Yibo Zhang, Jieqiong Cao, Yiqi Yang, Size Chen, Xinyuan Guan, Xiaojia Chen, An Hong

Journal: Int J Biol Sci

PubMed ID: 34671193

Doi: 10.7150/ijbs.62571

Products & Services: DNA Sequencing

Helicase-AID: A novel molecular device for base editing at random genomic loci

Authors: Jie Wang, Dongdong Zhao, Ju Li, Muzi Hu, Xiuqing Xin, Marcus A Price, Qingyan Li, Li Liu, Siwei Li, Susan J Rosser, Chunzhi Zhang, Changhao Bi, Xueli Zhang

Journal: Metab Eng

PubMed ID: 34411701

Doi: 10.1016/j.ymben.2021.08.005

Products & Services: DNA Sequencing

Sclerotinia sclerotiorum Thioredoxin1 (SsTrx1) is required for pathogenicity and oxidative stress tolerance

Authors: Kusum Rana, Yijuan Ding, Surinder S Banga, Hongmei Liao, Siqi Zhao, Yang Yu, Wei Qian

Journal: Mol Plant Pathol

PubMed ID: 34459563

Doi: 10.1111/mpp.13127

Products & Services: Custom RNAi Services

Expression and characterization of a novel lipase from Bacillus licheniformis NCU CS-5 for application in enhancing fatty acids flavor release for low-fat cheeses

Authors: Junxin Zhao, Maomao Ma, Xianghui Yan, Guohua Zhang, Jiaheng Xia, Guibing Zeng, Wenran Tian, Xianliang Bao, Zheling Zeng, Ping Yu, Deming Gong

Journal: Food Chem

PubMed ID: 34438173

Doi: 10.1016/j.foodchem.2021.130868

Products & Services: Codon Optimization

Determine genetic variations in heat shock factor gene family (HSFs) and study their effect on the functional and structural characterization of protein in Tali goat

Authors: Elham Rezvannejad, Seyed Azim Mousavizadeh, Safa Lotfi, Najmeh Kargar

Journal: Anim Biotechnol

PubMed ID: 34370605

Doi: 10.1080/10495398.2021.1954935

Molecular Context of Dopa Influences Adhesion of Mussel-Inspired Peptides

Authors: George D Degen, Keila C Cunha, Zachary A Levine, J Herbert Waite, Joan-Emma Shea

Journal: J Phys Chem B

PubMed ID: 34459591

Doi: 10.1021/acs.jpcb.1c05218

Products & Services: Catalog Peptides

Low molecular weight fucoidan attenuating pulmonary fibrosis by relieving inflammatory reaction and progression of epithelial-mesenchymal transition

Authors: Ning Wu, Zhi Li, Jing Wang, Lihua Geng, Yang Yue, Zhenzhen Deng, Qingchi Wang, Quanbin Zhang

Journal: Carbohydr Polym

PubMed ID: 34560978

Doi: 10.1016/j.carbpol.2021.118567

Products & Services: Recombinant Proteins

Miro1 functions as an inhibitory regulator of MFN at elevated mitochondrial Ca levels

Authors: Ferdinand F Fatiga, Li-Jie Wang, Tian Hsu, Jenica Irish Capuno, Chi-Yu Fu

Journal: J Cell Biochem

PubMed ID: 34431132

Doi: 10.1002/jcb.30138

Products & Services: Catalog Antibody

Light-Responsive Dynamic Protein Hydrogels Based on LOVTRAP

Authors: Tianyu Duan, Qingyuan Bian, Hongbin Li

Journal: Langmuir

PubMed ID: 34396769

Doi: 10.1021/acs.langmuir.1c01699

Products & Services: Catalog Antibody

Merlin functions as a critical regulator in Staphylococcus aureus-induced osteomyelitis

Authors: Zubin Zhou, Yuanliang Chen, Hong Sung Min, Yongbai Wan, Haojie Shan, Yiwei Lin, Wenyang Xia, Fuli Yin, Chaolai Jiang, Xiaowei Yu

Journal: J Cell Physiol

PubMed ID: 34378805

Doi: 10.1002/jcp.30550

Products & Services: Custom DNA/RNA Oligos

Quantification of protein cargo loading into engineered extracellular vesicles at single-vesicle and single-molecule resolution

Authors: Andreia M Silva, Elisa Lázaro-Ibáñez, Anders Gunnarsson, Aditya Dhande, George Daaboul, Ben Peacock, Xabier Osteikoetxea, Nikki Salmond, Kristina Pagh Friis, Olga Shatnyeva, Niek Dekker

Journal: J Extracell Vesicles

PubMed ID: 34377376

Doi: 10.1002/jev2.12130

Products & Services: Proteins, Expression, Isolation and Analysis

An Ancestral Retrovirus Envelope Protein Regulates Persistent Gammaherpesvirus Lifecycles

Authors: Tiffany R Frey, Ibukun A Akinyemi, Eric M Burton, Sumita Bhaduri-McIntosh, Michael T McIntosh

Journal: Front Microbiol

PubMed ID: 34434177

Doi: 10.3389/fmicb.2021.708404

Products & Services: Gene Synthesis

Human Fibrinogen Inhibits Amyloid Assembly of Most Phenol-Soluble Modulins from

Authors: Zahra Najarzadeh, Janni Nielsen, Azad Farzadfard, Vita Sereikaite, Kristian Strømgaard, Rikke Louise Meyer, Daniel Erik Otzen

Journal: ACS Omega

PubMed ID: 34497891

Doi: 10.1021/acsomega.1c02333

Products & Services: Peptide Synthesis

() Could Inhibit the Proliferation of Nucleopolyhedrovirus through Promoting Apoptosis

Authors: Jie Wang, Lin-Bao Zhu, Yan Ma, Ying-Xue Liu, Hui-Hua Cao, Yu-Ling Wang, Xue Kong, Zhi-Hao Huang, Han-Dan Zhu, Yan-Xiang Wang, Shi-Huo Liu, Jia-Ping Xu

Journal: Insects

PubMed ID: 34442307

Doi: 10.3390/insects12080743

Products & Services: Recombinant Antibody Expression

Coleopteran-specific StaufenC functions like Loquacious-PD in dsRNA processing

Authors: Kyungbo Kim, Jinmo Koo, June-Sun Yoon, Subba Reddy Palli

Journal: RNA Biol

PubMed ID: 34376105

Doi: 10.1080/15476286.2021.1960687

Products & Services: Recombinant Antibody Expression

Nintedanib downregulates the transition of cultured systemic sclerosis fibrocytes into myofibroblasts and their pro-fibrotic activity

Authors: Maurizio Cutolo, Emanuele Gotelli, Paola Montagna, Samuele Tardito, Sabrina Paolino, Carmen Pizzorni, Alberto Sulli, Vanessa Smith, Stefano Soldano

Journal: Arthritis Res Ther

PubMed ID: 34344444

Doi: 10.1186/s13075-021-02555-2

Products & Services: Proteins, Expression, Isolation and Analysis

Hippocampal overexpression of NOS1AP promotes endophenotypes related to mental disorders

Authors: Florian Freudenberg, Esin Candemir, Xufeng Chen, Li-Li Li, Dilhan Esen-Sehir, Nicole Schenk, Makoto Kinoshita, Lena Grünewald, Veronika Frerichs, Nikolai Fattakhov, Jessica Manchen, Solmaz Bikas, Anita Kumar, Aet OLeary, David A Slattery, Jakob von Engelhardt, Michael J Courtney, Andreas Reif

Journal: EBioMedicine

PubMed ID: 34455393

Doi: 10.1016/j.ebiom.2021.103565

Products & Services: Proteins, Expression, Isolation and Analysis

Refining the N-Termini of the SARS-CoV-2 Spike Protein and Its Discrete Receptor-Binding Domain

Authors: Robert A D'Ippolito, Matthew R Drew, Jennifer Mehalko, Kelly Snead, Vanessa Wall, Zoe Putman, Dominic Esposito, Caroline J DeHart

Journal: J Proteome Res

PubMed ID: 34379411

Doi: 10.1021/acs.jproteome.1c00349

Products & Services: Proteins, Expression, Isolation and Analysis

Structure of a meiosis-specific complex central to BRCA2 localization at recombination sites

Authors: Devon F Pendlebury, Jingjing Zhang, Ritvija Agrawal, Hiroki Shibuya, Jayakrishnan Nandakumar

Journal: Nat Struct Mol Biol

PubMed ID: 34373645

Doi: 10.1038/s41594-021-00635-0

Products & Services: Proteins, Expression, Isolation and Analysis

Tandem Mass Spectrometry as Strategy for the Selective Identification and Quantification of the Amyloid Precursor Protein Tyr682 Residue Phosphorylation Status in Human Blood Mononuclear Cells

Authors: Pierluigi Reveglia, Rosarita Nasso, Antonella Angiolillo, Lucia Lecce, Carmela Paolillo, Samantha De Tullio, Monica Gelzo, Alfonso Di Costanzo, Carmela Matrone, Gaetano Corso

Journal: Biomolecules

PubMed ID: 34572510

Doi: 10.3390/biom11091297

Products & Services: Peptide Synthesis

HLA Class II Polymorphisms Modulate Gut Microbiota and Experimental Autoimmune Encephalomyelitis Phenotype

Authors: Shailesh K Shahi, Soham Ali, Camille M Jaime, Natalya V Guseva, Ashutosh K Mangalam

Journal: Immunohorizons

PubMed ID: 34380664

Doi: 10.4049/immunohorizons.2100024

Products & Services: Peptide Synthesis

CD4+ T cells in the lungs of acute sarcoidosis patients recognize an Aspergillus nidulans epitope

Authors: Sarah A Greaves, Avinash Ravindran, Radleigh G Santos, Lan Chen, Michael T Falta, Yang Wang, Angela M Mitchell, Shaikh M Atif, Douglas G Mack, Alex N Tinega, Lisa A Maier, Shaodong Dai, Clemencia Pinilla, Johan Grunewald, Andrew P Fontenot

Journal: J Exp Med

PubMed ID: 34410304

Doi: 10.1084/jem.20210785

Products & Services: Peptide Library Services

Evolutionary and functional relationships in the ribosome biogenesis SBDS and EFL1 protein families

Authors: Alfonso Méndez-Godoy, Daniel García-Montalvo, León P Martínez-Castilla, Nuria Sánchez-Puig

Journal: Mol Genet Genomics

PubMed ID: 34453201

Doi: 10.1007/s00438-021-01814-w

Products & Services: PCR Cloning and Subcloning

New insights into the acetate uptake transporter (AceTr) family: Unveiling amino acid residues critical for specificity and activity

Authors: Toni Rendulić, João Alves, João Azevedo-Silva, Isabel Soares-Silva, Margarida Casal

Journal: Comput Struct Biotechnol J

PubMed ID: 34471488

Doi: 10.1016/j.csbj.2021.08.002

Products & Services: ORF cDNA Clones/MolecularCloud

Double-Stranded RNA-Degrading Enzymes Reduce the Efficiency of RNA Interference in

Authors: Jin-Zhi Chen, Ying-Xia Jiang, Miao-Wen Li, Jian-Wen Li, Ben-Hu Zha, Guang Yang

Journal: Insects

PubMed ID: 34442278

Doi: 10.3390/insects12080712

Products & Services: Monoclonal Antibody Services

Dynamic Changes in the Levels of Amyloid-β Species in the Brain and Periphery of APP/PS1 Mice and Their Significance for Alzheimer's Disease

Authors: Liding Zhang, Changwen Yang, Yanqing Li, Shiqi Niu, Xiaohan Liang, Zhihong Zhang, Qingming Luo, Haiming Luo

Journal: Front Mol Neurosci

PubMed ID: 34512259

Doi: 10.3389/fnmol.2021.723317

Products & Services: Monoclonal Antibody Services Catalog Peptides

Compound heterozygosis in AADC deficiency: A complex phenotype dissected through comparison among heterodimeric and homodimeric AADC proteins

Authors: Carmen Longo, Riccardo Montioli, Giovanni Bisello, Luana Palazzi, Mario Mastrangelo, Heiko Brennenstuhl, Patrizia Polverino de Laureto, Thomas Opladen, Vincenzo Leuzzi, Mariarita Bertoldi

Journal: Mol Genet Metab

PubMed ID: 34479793

Doi: 10.1016/j.ymgme.2021.08.011

Products & Services: Monoclonal Antibody Services

Generation and characterization of a humanized anti-IL-17A rabbit monoclonal antibody

Authors: Wei Chen, Yong Kong, Wang Li, Yi Zhou, Meijuan Wu, Tao Chen, Yiliang Wu, Huaiyao Qiao, Zhihua Qiu, Jiwan Qiu

Journal: Protein Expr Purif

PubMed ID: 34363980

Doi: 10.1016/j.pep.2021.105950

Products & Services: Mammalian Expression

Knockdown of miR-125b-5p inhibits the proliferation and invasion of gastric carcinoma cells by targeting RYBP

Authors: Fu-E Jin, Bo Xie, Hong-Zhen Xian, Ji-Hai Wang

Journal: Kaohsiung J Med Sci

PubMed ID: 34337862

Doi: 10.1002/kjm2.12425

Products & Services: GenParts™ DNA Fragments

Structure, Antigenic Properties, and Highly Efficient Assembly of PCV4 Capsid Protein

Authors: Dongliang Wang, Jinhui Mai, Bo Lei, Yingjie Zhang, Yi Yang, Naidong Wang

Journal: Front Vet Sci

PubMed ID: 34504886

Doi: 10.3389/fvets.2021.695466

Products & Services: Gene Synthesis

Metabolic impairment of non-small cell lung cancers by mitochondrial HSPD1 targeting

Authors: Beatrice Parma, Vignesh Ramesh, Paradesi Naidu Gollavilli, Aarif Siddiqui, Luisa Pinna, Annemarie Schwab, Sabine Marschall, Shuman Zhang, Christian Pilarsky, Francesca Napoli, Marco Volante, Sophia Urbanczyk, Dirk Mielenz, Henrik Daa Schrøder, Marc Stemmler, Heiko Wurdak, Paolo Ceppi

Journal: J Exp Clin Cancer Res

PubMed ID: 34364401

Doi: 10.1186/s13046-021-02049-8

Products & Services: GenCrispr Cas9 Genome Editing

Industry updates from the field of stem cell research and regenerative medicine in June 2021

Authors: Dusko Ilic, Mirjana Liovic

Journal: Regen Med

PubMed ID: 34387128

Doi: 10.2217/rme-2021-0097

Products & Services: GenCrispr Cas9 Genome Editing

P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway

Authors: Limei Yan, Zeping He, Wei Li, Ning Liu, Song Gao

Journal: Cell Cycle

PubMed ID: 34382920

Doi: 10.1080/15384101.2021.1963910

Products & Services: DNA Sequencing

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