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Alteration of Allergen Fold of Bos d 5 into a Hypoallergenic Vaccine for Immunotherapy of Cow's Milk Allergy

Authors: Yaqiong Cui, Yang Yu, Shuxiang Lin, Li Xu, Liuxu Li, Chunquan Cai, Huiqiang Li

Journal: Int Arch Allergy Immunol

PubMed ID: 34515139

Doi: 10.1159/000517998

Products & Services: Bacterial Expression

Enhanced tumor homing of pathogen-mimicking liposomes driven by R848 stimulation: A new platform for synergistic oncology therapy

Authors: Xiaobei Cheng, Pei Yu, Xiang Zhou, Jiale Zhu, Yubao Han, Chao Zhang, Lingyi Kong

Journal: Acta Pharm Sin B

PubMed ID: 35256955

Doi: 10.1016/j.apsb.2021.08.018

Products & Services: Catalog Antibody

Molecular Cloning and Expression Profile of Class Genes Related to Sepal Development in

Authors: Zhuoxing Liu, Dasheng Zhang, Weiwei Zhang, Lei Xiong, Qingqing Liu, Fengluan Liu, Hanchun Li, Xiangjie An, Lijie Cui, Daike Tian

Journal: Plants (Basel)

PubMed ID: 34451674

Doi: 10.3390/plants10081629

Products & Services: GenParts™ DNA Fragments

Enhanced genome editing efficiency of CRISPR PLUS: Cas9 chimeric fusion proteins

Authors: Jongjin Park, Jiyoung Yoon, Daekee Kwon, Mi-Jung Han, Sunmee Choi, Slki Park, Junghyuk Lee, Kiwook Lee, Jaehwan Lee, Seunghee Lee, Kyung-Sun Kang, Sunghwa Choe

Journal: Sci Rep

PubMed ID: 34376729

Doi: 10.1038/s41598-021-95406-8

Products & Services: Mammalian Expression

Evidence that class I glutamine amidotransferase, GAT1_21, acts as a glutaminase in roots of Arabidopsis thaliana

Authors: Shrikaar Kambhampati, Aga Pajak, Frédéric Marsolais

Journal: Plant Sci

PubMed ID: 34620437

Doi: 10.1016/j.plantsci.2021.111033

Products & Services: Proteins, Expression, Isolation and Analysis

Der p 38 Is a Bidirectional Regulator of Eosinophils and Neutrophils in Allergy

Authors: Min Hwa Hong, Ayesha Kashif, Geunyeong Kim, Beom Seok Park, Na Rae Lee, Eun Ju Yang, Ji Young Mun, Hyosun Choi, Sang-Hoon Kim, Hyun Jik Kim, Soo Jin Lee, Ji-Sook Lee, Yujin Hong, In Sik Kim

Journal: J Immunol

PubMed ID: 34462314

Doi: 10.4049/jimmunol.2001144

Products & Services: Endotoxin Detection & Removal System

Quantitative SARS-CoV-2 Spike Antibody Response in COVID-19 Patients Using Three Fully Automated Immunoassays and a Surrogate Virus Neutralization Test

Authors: Yoonjoo Kim, Ji Hyun Lee, Geon Young Ko, Ji Hyeong Ryu, Joo Hee Jang, Hyunjoo Bae, Seung-Hyo Yoo, Ae-Ran Choi, Jin Jung, Jongmin Lee, Eun-Jee Oh

Journal: Diagnostics (Basel)

PubMed ID: 34441430

Doi: 10.3390/diagnostics11081496

Products & Services: Proteins, Expression, Isolation and Analysis

Novel Host Recognition Mechanism of the K1 Capsule-Specific Phage of : Capsular Polysaccharide as the First Receptor and Lipopolysaccharide as the Secondary Receptor

Authors: Qianwen Gong, Xuhang Wang, Haosheng Huang, Yu Sun, Xinjie Qian, Feng Xue, Jianluan Ren, Jianjun Dai, Fang Tang

Journal: J Virol

PubMed ID: 34191582

Doi: 10.1128/JVI.00920-21

Products & Services: Proteins, Expression, Isolation and Analysis

Targeted and activatable nanosystem for fluorescent and optoacoustic imaging of immune-mediated inflammatory diseases and therapy via inhibiting NF-κB/NLRP3 pathways

Authors: Lihe Sun, Juan Ouyang, Zhuo Zeng, Cheng Zeng, Yunqing Ma, Fang Zeng, Shuizhu Wu

Journal: Bioact Mater

PubMed ID: 34901531

Doi: 10.1016/j.bioactmat.2021.08.010

Products & Services: Proteins, Expression, Isolation and Analysis

HIV-1 Nef interacts with the cyclin K/CDK13 complex to antagonize SERINC5 for optimal viral infectivity

Authors: Qingqing Chai, Sunan Li, Morgan K Collins, Rongrong Li, Iqbal Ahmad, Silas F Johnson, Dylan A Frabutt, Zhichang Yang, Xiaojing Shen, Liangliang Sun, Jian Hu, Judd F Hultquist, B Matija Peterlin, Yong-Hui Zheng

Journal: Cell Rep

PubMed ID: 34380030

Doi: 10.1016/j.celrep.2021.109514

Products & Services: Catalog Peptides

Rapid selection of HIV envelopes that bind to neutralizing antibody B cell lineage members with functional improbable mutations

Authors: Olivia Swanson, Brianna Rhodes, Avivah Wang, Shi-Mao Xia, Robert Parks, Haiyan Chen, Aja Sanzone, Melissa Cooper, Mark K Louder, Bob C Lin, Nicole A Doria-Rose, Mattia Bonsignori, Kevin O Saunders, Kevin Wiehe, Barton F Haynes, Mihai L Azoitei

Journal: Cell Rep

PubMed ID: 34407396

Doi: 10.1016/j.celrep.2021.109561

Products & Services: Custom Vector Construction

TET3 promotes AML growth and epigenetically regulates glucose metabolism and leukemic stem cell associated pathways

Authors: Alex Jose Pulikkottil, Shiva Bamezai, Tobias Ammer, Fabian Mohr, Kristin Feder, Naidu M Vegi, Tamoghna Mandal, Ursula Kohlhofer, Leticia Quintanilla-Martinez, Amit Sinha, Christian Buske, Vijay P S Rawat

Journal: Leukemia

PubMed ID: 34462525

Doi: 10.1038/s41375-021-01390-3

Products & Services: Stable Cell Lines

Randomized Trial of a Third Dose of mRNA-1273 Vaccine in Transplant Recipients

Authors: Victoria G Hall, Victor H Ferreira, Terrance Ku, Matthew Ierullo, Beata Majchrzak-Kita, Cecilia Chaparro, Nazia Selzner, Jeffrey Schiff, Michael McDonald, George Tomlinson, Vathany Kulasingam, Deepali Kumar, Atul Humar

Journal: N Engl J Med

PubMed ID: 34379917

Doi: 10.1056/NEJMc2111462

Products & Services: SARS-CoV-2 qRT-PCR Detection Assay

Context-Specific Function of the Engineered Peptide Domain of PHPB

Authors: R Alexander Martino, Edwin C Fluck, Jacqueline Murphy, Qiang Wang, Henry Hoff, Ruth A Pumroy, Claudia Y Lee, Joshua J Sims, Soumitra Roy, Vera Y Moiseenkova-Bell, James M Wilson

Journal: J Virol

PubMed ID: 34346767

Doi: 10.1128/JVI.01164-21

Products & Services: Recombinant Antibody Expression

Dihydrotanshinone I inhibits the growth of hepatoma cells by direct inhibition of Src

Authors: Xiao-Li Jiang, Bo Deng, Sui-Hui Deng, Min Cai, Wen-Jun Ding, Zhang-Bin Tan, Rui-Xue Chen, You-Cai Xu, Hong-Lin Xu, Shuang-Wei Zhang, Shi-Qing Zhang, Bin Liu, Jing-Zhi Zhang

Journal: Phytomedicine

PubMed ID: 34538671

Doi: 10.1016/j.phymed.2021.153705

Products & Services: Proteins, Expression, Isolation and Analysis

Efficient Dicer processing of virus-derived double-stranded RNAs and its modulation by RIG-I-like receptor LGP2

Authors: Yuqiang Zhang, Yan Xu, Yunpeng Dai, Zhe Li, Jiaxing Wang, Zhi Ye, Yanxin Ren, Hua Wang, Wan-Xiang Li, Jinfeng Lu, Shou-Wei Ding, Yang Li

Journal: PLoS Pathog

PubMed ID: 34343211

Doi: 10.1371/journal.ppat.1009790

Products & Services: Proteins, Expression, Isolation and Analysis

Multigenerational selection towards longevity changes the protective role of vitamin C against graphene oxide-induced oxidative stress in house crickets

Authors: Barbara Flasz, Marta Dziewięcka, Andrzej Kędziorski, Monika Tarnawska, Jan Augustyniak, Maria Augustyniak

Journal: Environ Pollut

PubMed ID: 34416498

Doi: 10.1016/j.envpol.2021.117996

Products & Services: Proteins, Expression, Isolation and Analysis

Structure of a Minimal α-Carboxysome-Derived Shell and Its Utility in Enzyme Stabilization

Authors: Yong Quan Tan, Samson Ali, Bo Xue, Wei Zhe Teo, Lay Hiang Ling, Maybelle Kho Go, Hong Lv, Robert C Robinson, Akihiro Narita, Wen Shan Yew

Journal: Biomacromolecules

PubMed ID: 34384019

Doi: 10.1021/acs.biomac.1c00533

Products & Services: Proteins, Expression, Isolation and Analysis

Combined 4-1BB and ICOS co-stimulation improves anti-tumor efficacy and persistence of dual anti-CD19/CD20 chimeric antigen receptor T cells

Authors: Ying Wang, Kailun Zhong, Jun Ke, Xi Chen, Yi Chen, Wangyun Shu, Chunhuan Chen, Shan Hu, Xiaoke Sun, Haibin Huang, Chong Luo, Lifang Liu, Jiaming Yang, Yongke Zhang, Huijun Zhi

Journal: Cytotherapy

PubMed ID: 33863641

Doi: 10.1016/j.jcyt.2021.02.117

Products & Services: Proteins, Expression, Isolation and Analysis

Novel Glutamate-Putrescine Ligase Activity in : A New Function for Gene

Authors: Verónica Rodríguez-Herrero, Arnau Peris, Mónica Camacho, Vanesa Bautista, Julia Esclapez, María-José Bonete

Journal: Biomolecules

PubMed ID: 34439822

Doi: 10.3390/biom11081156

Products & Services: Polyclonal Antibody Services

Unbiased proteomic mapping of the LINE-1 promoter using CRISPR Cas9

Authors: Erica M Briggs, Paolo Mita, Xiaoji Sun, Susan Ha, Nikita Vasilyev, Zev R Leopold, Evgeny Nudler, Jef D Boeke, Susan K Logan

Journal: Mob DNA

PubMed ID: 34425899

Doi: 10.1186/s13100-021-00249-9

Products & Services: Plasmid DNA Preparation

Longitudinal Assessment of Cytokine Expression and Plasminogen Activation in Hantavirus Cardiopulmonary Syndrome Reveals Immune Regulatory Dysfunction in End-Stage Disease

Authors: Peter Simons, Yan Guo, Virginie Bondu, Susan L Tigert, Michelle Harkins, Samuel Goodfellow, Cana Tompkins, Devon Chabot-Richards, Xuexian O Yang, Laura Gonzalez Bosc, Steven Bradfute, Daniel A Lawrence, Tione Buranda

Journal: Viruses

PubMed ID: 34452463

Doi: 10.3390/v13081597

Products & Services: Plasmid DNA Preparation

Ability of nucleoside-modified mRNA to encode HIV-1 envelope trimer nanoparticles

Authors: Zekun Mu, Kevin Wiehe, Kevin O Saunders, Rory Henderson, Derek W Cain, Robert Parks, Diana Martik, Katayoun Mansouri, Robert J Edwards, Amanda Newman, Xiaozhi Lu, Shi-Mao Xia, Mattia Bonsignori, David Montefiori, Qifeng Han, Sravani Venkatayogi, Tyler Evangelous, Yunfei Wang, Wes Rountree, Ying Tam, Christopher Barbosa, S Munir Alam, Wilton B Williams, Norbert Pardi, Drew Weissman, Barton F Haynes

Journal: biorxiv

PubMed ID: 34401876

Doi: 10.1101/2021.08.09.455714

Products & Services: Plasmid DNA Preparation

A truncated glycoprotein G vaccine formulated with Advax-CpG adjuvant provides protection of mice against genital herpes simplex virus 2 infection

Authors: Staffan Görander, Yoshikazu Honda-Okubo, Malin Bäckström, Jeremy Baldwin, Tomas Bergström, Nikolai Petrovsky, Jan-Åke Liljeqvist

Journal: Vaccine

PubMed ID: 34456075

Doi: 10.1016/j.vaccine.2021.08.050

Products & Services: Plasmid DNA Preparation

DNA-guided photoactivatable probe-based chemical proteomics reveals the reader protein of mRNA methylation

Authors: Yepei Huang, Xue Bai, Zhenchang Guo, Hanyang Dong, Yun Fu, Hui Zhang, Guijin Zhai, Shanshan Tian, Ye Wang, Kai Zhang

Journal: iScience

PubMed ID: 34553132

Doi: 10.1016/j.isci.2021.103046

Products & Services: Plasmid DNA Preparation

Interaction of Antimicrobial Peptide Ponericin W1, Thanatin, and Mastatopara-S with Genomic DNA

Authors: Hongyan Zhang, Sha Liu, Xindan Li, Wenjun Wang, Lili Deng, Kaifang Zeng

Journal: Foods

PubMed ID: 34441696

Doi: 10.3390/foods10081919

Products & Services: Peptide Tools

Optimization of antigen-specific CD8 T cell activation conditions for infectious diseases including COVID-19

Authors: Chanchan Xiao, Congling Qiu, Jieping Deng, Jiezhou Ye, Lijuan Gao, Jun Su, Oscar Junhong Luo, Pengcheng Wang, Guobing Chen

Journal: STAR Protoc

PubMed ID: 34414379

Doi: 10.1016/j.xpro.2021.100789

Products & Services: Peptide Synthesis

Dual concentration-dependent effect of ascorbic acid on PAP(248-286) amyloid formation and SEVI-mediated HIV infection

Authors: Satabdee Mohapatra, Guru Krishna Kumar Viswanathan, Lukas Wettstein, Elad Arad, Ashim Paul, Vijay Kumar, Raz Jelinek, Jan Münch, Daniel Segal

Journal: RSC Chem Biol

PubMed ID: 34704058

Doi: 10.1039/d1cb00084e

Products & Services: Peptide Synthesis

Targeted genetic screening in bacteria with a Cas12k-guided transposase

Authors: Weizhong Chen, Ze-Hui Ren, Na Tang, Guoshi Chai, Hongyuan Zhang, Yifei Zhang, Jiacheng Ma, Zhaowei Wu, Xia Shen, Xingxu Huang, Guan-Zheng Luo, Quanjiang Ji

Journal: Cell Rep

PubMed ID: 34469724

Doi: 10.1016/j.celrep.2021.109635

Products & Services: PCR Cloning and Subcloning

Vaccination against the Protozoan Parasite Primes the Activation of Toll-like Receptors in Turkeys and Chickens Determined by a Set of Newly Developed Multiplex RT-qPCRs

Authors: Taniya Mitra, Beatrice Bramberger, Ivana Bilic, Michael Hess, Dieter Liebhart

Journal: Vaccines (Basel)

PubMed ID: 34579197

Doi: 10.3390/vaccines9090960

Products & Services: ORF cDNA Clones/MolecularCloud

Downregulation of miR-1-3p expression inhibits the hypertrophy and mineralization of chondrocytes in DDH

Authors: Rui Ding, Xijuan Liu, Jian Zhang, Jinghong Yuan, Sikuan Zheng, Xigao Cheng, Jingyu Jia

Journal: J Orthop Surg Res

PubMed ID: 34407854

Doi: 10.1186/s13018-021-02666-1

Products & Services: Mutant Libraries

Mapping human calreticulin regions important for structural stability

Authors: Evaldas Čiplys, Tautvydas Paškevičius, Eimantas Žitkus, Juras Bielskis, Raimundas Ražanskas, Tomas Šneideris, Vytautas Smirnovas, Algirdas Kaupinis, David J Tester, Michael J Ackerman, Peter Højrup, Marek Michalak, Gunnar Houen, Rimantas Slibinskas

Journal: Biochim Biophys Acta Proteins Proteom

PubMed ID: 34358706

Doi: 10.1016/j.bbapap.2021.140710

Products & Services: Mutant Libraries

Inhibition of Border Disease Virus Replication With Lentivirus-Mediated shRNAs

Authors: Mohammad Javad Hajihasani Arani, Azam Mokhtari, Behnaz Saffar, Leila Asadi Samani

Journal: Front Vet Sci

PubMed ID: 34447803

Doi: 10.3389/fvets.2021.708591

Products & Services: Molecular Biology Tools

Schizophrenia risk candidate protein ZNF804A interacts with STAT2 and influences interferon-mediated gene transcription in mammalian cells

Authors: Konrad Klockmeier, Eduardo Silva Ramos, Tamás Raskó, Adrián Martí Pastor, Erich E Wanker

Journal: J Mol Biol

PubMed ID: 34364876

Doi: 10.1016/j.jmb.2021.167184

Products & Services: Molecular Biology Tools

Pan-Sarbecovirus Neutralizing Antibodies in BNT162b2-Immunized SARS-CoV-1 Survivors

Authors: Chee-Wah Tan, Wan-Ni Chia, Barnaby E Young, Feng Zhu, Beng-Lee Lim, Wan-Rong Sia, Tun-Linn Thein, Mark I-C Chen, Yee-Sin Leo, David C Lye, Lin-Fa Wang

Journal: N Engl J Med

PubMed ID: 34407341

Doi: 10.1056/NEJMoa2108453

Products & Services: Molecular Biology Reagents

Early warning and rapid public health response to prevent COVID-19 outbreaks in long-term care facilities (LTCF) by monitoring SARS-CoV-2 RNA in LTCF site-specific sewage samples and assessment of antibodies response in this population: prospective study protocol

Authors: Bonita E Lee, Christopher Sikora, Douglas Faulder, Eleanor Risling, Lorie A Little, Yuanyuan Qiu, Tiejun Gao, Ross Bulat, Stephen Craik, Steve E Hrudey, Arto Ohinmaa, Carole A Estabrooks, Anne-Claude Gingras, Carmen Charlton, John Kim, Heidi Wood, Alyssia Robinson, Jamil N Kanji, Nathan Zelyas, Sheila F O'Brien, Steven Drews, Xiao-Li Pang

Journal: BMJ Open

PubMed ID: 34417219

Doi: 10.1136/bmjopen-2021-052282

Products & Services: Molecular Biology Reagents

Influenza Virus-like Particle (VLP) Vaccines Expressing the SARS-CoV-2 S Glycoprotein, S1, or S2 Domains

Authors: Ki-Back Chu, Hae-Ji Kang, Keon-Woong Yoon, Hae-Ahm Lee, Eun-Kyung Moon, Beom-Ku Han, Fu-Shi Quan

Journal: Vaccines (Basel)

PubMed ID: 34452044

Doi: 10.3390/vaccines9080920

Products & Services: DNA Sequencing

Metabolic Engineering of BD16 for Heterologous Expression of Synthetic Gene Cassette and L-Alanine Production in the Recombinant Strain Using Fed-Batch Fermentation

Authors: Anshula Sharma, Masafumi Noda, Masanori Sugiyama, Baljinder Kaur, Ajaz Ahmad

Journal: Foods

PubMed ID: 34441741

Doi: 10.3390/foods10081964

Products & Services: Custom Vector Construction

miRNA-451 regulates the NF-κB signaling pathway by targeting IKKβ to inhibit glioma cell growth

Authors: Yang Nan, Liyun Guo, Yingwei Zhen, Le Wang, Bingcheng Ren, Xingjie Chen, Yalin Lu, Kai Yu, Yue Zhong, Qiang Huang

Journal: Cell Cycle

PubMed ID: 34463194

Doi: 10.1080/15384101.2021.1969496

Products & Services: Custom Vector Construction

Litopenaeus vannamei peroxiredoxin 2-like is involved in WSSV infection by interaction with wsv089 and VP26

Authors: Xing-Chao Ren, Xiao-Ping Liu, Qing-Hui Liu

Journal: Dev Comp Immunol

PubMed ID: 34450129

Doi: 10.1016/j.dci.2021.104243

Products & Services: Custom Vector Construction

A continuous spectrophotometric assay for glutathione-independent glyoxalases

Authors: Tomiris Mulikova, Zhanibek Bekkhozhin, Aizat Abdirassil, Darkhan Utepbergenov

Journal: Anal Biochem

PubMed ID: 34391725

Doi: 10.1016/j.ab.2021.114317

Products & Services: Custom Vector Construction

Radiation-Induced Phosphorylation of a Prion-Like Domain Regulates Transformation by FUS-CHOP

Authors: Mark Chen, Joseph P Foster, Ian C Lock, Nathan H Leisenring, Andrea R Daniel, Warren Floyd, Eric Xu, Ian J Davis, David G Kirsch

Journal: Cancer Res

PubMed ID: 34385184

Doi: 10.1158/0008-5472.CAN-20-1497

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An ester bond underlies the mechanical strength of a pathogen surface protein

Authors: Hai Lei, Quan Ma, Wenfei Li, Jing Wen, Haibo Ma, Meng Qin, Wei Wang, Yi Cao

Journal: Nat Commun

PubMed ID: 34426584

Doi: 10.1038/s41467-021-25425-6

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Meet the authors: Michael Ranes and Sebastian Guettler

Authors:

Journal: Mol Cell

PubMed ID: 34416135

Doi: 10.1016/j.molcel.2021.08.002

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Dynamics of SARS-CoV-2 Spike Proteins in Cell Entry: Control Elements in the Amino-Terminal Domains

Authors: Enya Qing, Tom Kicmal, Binod Kumar, Grant M Hawkins, Emily Timm, Stanley Perlman, Tom Gallagher

Journal: MBio

PubMed ID: 34340537

Doi: 10.1128/mBio.01590-21

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Deep survey for designing a vaccine against SARS-CoV-2 and its new mutations

Authors: Bahareh Vakili, Ashkan Bagheri, Manica Negahdaripour

Journal: Biologia (Bratisl)

PubMed ID: 34421121

Doi: 10.1007/s11756-021-00866-y

Products & Services: Codon Optimization

Compact RNA editors with small Cas13 proteins

Authors: Soumya Kannan, Han Altae-Tran, Xin Jin, Victoria J Madigan, Rachel Oshiro, Kira S Makarova, Eugene V Koonin, Feng Zhang

Journal: Nat Biotechnol

PubMed ID: 34462587

Doi: 10.1038/s41587-021-01030-2

Products & Services: Codon Optimization

Structural mechanism of calcium-mediated hormone recognition and Gβ interaction by the human melanocortin-1 receptor

Authors: Shanshan Ma, Yan Chen, Antao Dai, Wanchao Yin, Jia Guo, Dehua Yang, Fulai Zhou, Yi Jiang, Ming-Wei Wang, H Eric Xu

Journal: Cell Res

PubMed ID: 34453129

Doi: 10.1038/s41422-021-00557-y

Products & Services: Catalog Peptides

Structure of the Human Cholesterol Transporter ABCG1

Authors: Liga Skarda, Julia Kowal, Kaspar P Locher

Journal: J Mol Biol

PubMed ID: 34461069

Doi: 10.1016/j.jmb.2021.167218

Products & Services: Catalog Peptides

Development of a chimeric protein based on a proteomic approach for the serological diagnosis of human tegumentary leishmaniasis

Authors: Guilherme Caetano Garcia, Ana Maria Ravena Severino Carvalho, Mariana Costa Duarte, Matheus Fernandes Costa E Silva, Fernanda Alvarenga Cardoso Medeiros, Eduardo Antonio Ferraz Coelho, Dênia Monteiro de Moura Franco, Denise Utsch Gonçalves, Tiago Antônio de Oliveira Mendes, Daniel Menezes-Souza

Journal: Appl Microbiol Biotechnol

PubMed ID: 34432132

Doi: 10.1007/s00253-021-11518-1

Products & Services: Bacterial Expression

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