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A GRA2 minimal promoter improves the efficiency of TATi / Tet-Off conditional regulation of gene expression in Toxoplasma gondii

Authors: Mohammad Farouq Sharifpour, Shadi Khadiv, Markus Meissner, Milton M McAllister

Journal: Mol Biochem Parasitol.

PubMed ID: 34051228

Doi: 10.1016/j.molbiopara.2021.111384

Products & Services: Gene Synthesis PCR Cloning and Subcloning

Bisulfite Amplicon Sequencing Can Detect Glia and Neuron Cell-Free DNA in Blood Plasma

Authors: Zac Chatterton, Natalia Mendelev, Sean Chen, Walter Carr, Gary H Kamimori, Yongchao Ge, Andrew J Dwork, Fatemeh Haghighi

Journal: Front Mol Neurosci

PubMed ID: 34276305

Doi: 10.3389/fnmol.2021.672614

Products & Services: Monoclonal Antibody Services

A single residue can modulate nanocage assembly in salt dependent ferritin

Authors: Mantu Kumar, Joanna Markiewicz-Mizera, Julian David Janna Olmos, Piotr Wilk, Przemysław Grudnik, Artur P Biela, Małgorzata Jemioła-Rzemińska, Andrzej Górecki, Soumyananda Chakraborti, Jonathan G Heddle

Journal: Nanoscale

PubMed ID: 34195748

Doi: 10.1039/d1nr01632f

Products & Services: Plasmid DNA Preparation

Human low-density lipoprotein receptor plays an important role in hepatitis B virus infection

Authors: Yingying Li, Guangxiang Luo

Journal: PLoS Pathog

PubMed ID: 34293069

Doi: 10.1371/journal.ppat.1009722

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Caenorhabditis elegans RMI2 functional homolog-2 (RMIF-2) and RMI1 (RMH-1) have both overlapping and distinct meiotic functions within the BTR complex

Authors: Maria Velkova, Nicola Silva, Maria Rosaria Dello Stritto, Alexander Schleiffer, Pierre Barraud, Markus Hartl, Verena Jantsch

Journal: PLoS Genet

PubMed ID: 34252074

Doi: 10.1371/journal.pgen.1009663

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Molecular and biological characterization of severe strain infecting soybean in India

Authors: Nagamani Sandra, Ankita Tripathi, S K Lal, Bikash Mandal, Rakesh Kumar Jain

Journal: 3 Biotech

PubMed ID: 34458057

Doi: 10.1007/s13205-021-02925-2

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The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance

Authors: James M Murithi, Ioanna Deni, Charisse Flerida A Pasaje, John Okombo, Jessica L Bridgford, Nina F Gnädig, Rachel L Edwards, Tomas Yeo, Sachel Mok, Anna Y Burkhard, Olivia Coburn-Flynn, Eva S Istvan, Tomoyo Sakata-Kato, Maria G Gomez-Lorenzo, Annie N Cowell, Kathryn J Wicht, Claire Le Manach, Gavreel F Kalantarov, Sumanta Dey, Maëlle Duffey, Benoît Laleu, Amanda K Lukens, Sabine Ottilie, Manu Vanaerschot, Ilya N Trakht, Francisco-Javier Gamo, Dyann F Wirth, Daniel E Goldberg, Audrey R Odom John, Kelly Chibale, Elizabeth A Winzeler, Jacquin C Niles, David A Fidock

Journal: Cell Chem Biol

PubMed ID: 34233174

Doi: 10.1016/j.chembiol.2021.06.006

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YB-1 Is Altered in Pregnancy-Associated Disorders and Affects Trophoblast in Vitro Properties via Alternation of Multiple Molecular Traits

Authors: Violeta Stojanovska, Aneri Shah, Katja Woidacki, Florence Fischer, Mario Bauer, Jonathan A Lindquist, Peter R Mertens, Ana C Zenclussen

Journal: Int J Mol Sci

PubMed ID: 34281280

Doi: 10.3390/ijms22137226

Products & Services: Proteins, Expression, Isolation and Analysis

Genome-Wide Identification and Expression Analysis of Tomato Gene Family during Development and Stress

Authors: Lu Yang, Haohao Cao, Xiaoping Zhang, Liangxian Gui, Qiang Chen, Gui Qian, Jiaxin Xiao, Zhengguo Li

Journal: Int J Mol Sci

PubMed ID: 34299327

Doi: 10.3390/ijms22147708

Products & Services: Protein Tools

Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth

Authors: Fangrui Wu, Shenyou Nie, Yuan Yao, Tong Huo, Xin Li, Xiaowei Wu, Jidong Zhao, Yi-Lun Lin, Yinjie Zhang, Qianxing Mo, Yongcheng Song

Journal: Theranostics

PubMed ID: 34373735

Doi: 10.7150/thno.56737

Products & Services: Mammalian Expression

Genomic identification of nitrogen assimilation-related genes and transcriptional characterization of their responses to nitrogen in allotetraploid rapeseed

Authors: Yue Wang, Ying-Peng Hua, Ting Zhou, Jin-Yong Huang, Cai-Peng Yue

Journal: Mol Biol Rep

PubMed ID: 34327662

Doi: 10.1007/s11033-021-06599-0

Products & Services: Protein Tools

Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor

Authors: Fenghui Zhao, Chao Zhang, Qingtong Zhou, Kaini Hang, Xinyu Zou, Yan Chen, Fan Wu, Qidi Rao, Antao Dai, Wanchao Yin, Dan-Dan Shen, Yan Zhang, Tian Xia, Raymond C Stevens, H Eric Xu, Dehua Yang, Lihua Zhao, Ming-Wei Wang

Journal: Elife

PubMed ID: 34254582

Doi: 10.7554/eLife.68719

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Functional interdependence of the actin nucleator Cobl and Cobl-like in dendritic arbor development

Authors: Maryam Izadi, Eric Seemann, Dirk Schlobinski, Lukas Schwintzer, Britta Qualmann, Michael M Kessels

Journal: Elife

PubMed ID: 34264190

Doi: 10.7554/eLife.67718

Products & Services: Proteins, Expression, Isolation and Analysis

HDAC inhibitors induce LIFR expression and promote a dormancy phenotype in breast cancer

Authors: Miranda E Clements, Lauren Holtslander, Courtney Edwards, Vera Todd, Samuel D R Dooyema, Kennady Bullock, Kensey Bergdorf, Cynthia A Zahnow, Roisin M Connolly, Rachelle W Johnson

Journal: Oncogene

PubMed ID: 34247191

Doi: 10.1038/s41388-021-01931-1

Products & Services: Plasmid DNA Preparation

Low efficiency of leucocyte plugging-based drug delivery to cancer in mice

Authors: Baifeng Qian, Andreas Termer, Christof M Sommer, Arianeb Mehrabi, Eduard Ryschich

Journal: Drug Deliv Transl Res

PubMed ID: 34319578

Doi: 10.1007/s13346-021-01028-y

Products & Services: Recombinant Proteins

Overexpression of Douglas-Fir () in Induces Embryonic Programs and Embryo-like Structures in the Mutant but Not in Wild Type Plants

Authors: Mariana A Vetrici, Dmytro P Yevtushenko, Santosh Misra

Journal: Plants (Basel)

PubMed ID: 34451571

Doi: 10.3390/plants10081526

Products & Services: Proteins, Expression, Isolation and Analysis

Structural basis for the constitutive activity and immunomodulatory properties of the Epstein-Barr virus-encoded G protein-coupled receptor BILF1

Authors: Naotaka Tsutsumi, Qianhui Qu, Maša Mavri, Maibritt S Baggesen, Shoji Maeda, Deepa Waghray, Christian Berg, Brian K Kobilka, Mette M Rosenkilde, Georgios Skiniotis, K Christopher Garcia

Journal: Immunity

PubMed ID: 34216564

Doi: 10.1016/j.immuni.2021.06.001

Products & Services: Custom Vector Construction

Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model

Authors: Johannes Gebert, Ozkan Gelincik, Mine Oezcan-Wahlbrink, Jason D Marshall, Alejandro Hernandez-Sanchez, Katharina Urban, Mark Long, Eduardo Cortes, Elena Tosti, Eva-Maria Katzenmaier, Yurong Song, Ali Elsaadi, Nan Deng, Eduardo Vilar, Vera Fuchs, Nina Nelius, Yan P Yuan, Aysel Ahadova, Shizuko Sei, Robert H Shoemaker, Asad Umar, Lei Wei, Song Liu, Peer Bork, Winfried Edelmann, Magnus von Knebel Doeberitz, Steven M Lipkin, Matthias Kloor

Journal: Gastroenterology

PubMed ID: 34224739

Doi: 10.1053/j.gastro.2021.06.073

Products & Services: Proteins, Expression, Isolation and Analysis

Mechanism of DNA Interaction and Translocation by the Replicase of a Circular Rep-Encoding Single-Stranded DNA Virus

Authors: Elvira Tarasova, Sonali Dhindwal, Matthew Popp, Sakeenah Hussain, Reza Khayat

Journal: MBio

PubMed ID: 34311576

Doi: 10.1128/mBio.00763-21

Products & Services: Codon Optimization

Fulvic acid enhances drought resistance in tea plants by regulating the starch and sucrose metabolism and certain secondary metabolism

Authors: Chen Qiu, Jianhao Sun, Jiazhi Shen, Shuning Zhang, Yiqian Ding, Zhongshuai Gai, Kai Fan, Lubin Song, Bo Chen, Zhaotang Ding, Yu Wang

Journal: J Proteomics

PubMed ID: 34298183

Doi: 10.1016/j.jprot.2021.104337

Products & Services: Protein Tools

Antibodies Targeting Two Epitopes in SARS-CoV-2 Neutralize Pseudoviruses with the Spike Proteins from Different Variants

Authors: Chee-Hing Yang, Hui-Chun Li, Wen-Han Lee, Shih-Yen Lo

Journal: Pathogens

PubMed ID: 34358019

Doi: 10.3390/pathogens10070869

Products & Services: Plasmid DNA Preparation

TIMELESS-TIPIN and UBXN-3 promote replisome disassembly during DNA replication termination in Caenorhabditis elegans

Authors: Yisui Xia, Ryo Fujisawa, Tom D Deegan, Remi Sonneville, Karim P M Labib

Journal: EMBO J

PubMed ID: 34269473

Doi: 10.15252/embj.2021108053

Products & Services: Codon Optimization

Site-Specific Steric Control of SARS-CoV-2 Spike Glycosylation

Authors: Joel D Allen, Himanshi Chawla, Firdaus Samsudin, Lorena Zuzic, Aishwary Tukaram Shivgan, Yasunori Watanabe, Wan-Ting He, Sean Callaghan, Ge Song, Peter Yong, Philip J M Brouwer, Yutong Song, Yongfei Cai, Helen M E Duyvesteyn, Tomas Malinauskas, Joeri Kint, Paco Pino, Maria J Wurm, Martin Frank, Bing Chen, David I Stuart, Rogier W Sanders, Raiees Andrabi, Dennis R Burton, Sai Li, Peter J Bond, Max Crispin

Journal: Biochemistry

PubMed ID: 34213308

Doi: 10.1021/acs.biochem.1c00279

Products & Services: Gene Synthesis

Seasonal Variation in Transcriptomic Profiling of Fully Developed Tuberous Roots Enriches Candidate Genes in Essential Metabolic Pathways and Phytohormone Signaling

Authors: Qianqian Xiang, Siyuan Hu, Ayalew Ligaba-Osena, Jiayao Yang, Fudan Tong, Wanli Guo

Journal: Front Plant Sci

PubMed ID: 34305963

Doi: 10.3389/fpls.2021.659645

Products & Services: Molecular Biology Tools

Genome-Wide Characterization of B-Box Gene Family and Its Roles in Responses to Light Quality and Cold Stress in Tomato

Authors: Xin Bu, Xiujie Wang, Jiarong Yan, Ying Zhang, Shunyuan Zhou, Xin Sun, Youxin Yang, Golam Jalal Ahammed, Yufeng Liu, Mingfang Qi, Feng Wang, Tianlai Li

Journal: Front Plant Sci

PubMed ID: 34290726

Doi: 10.3389/fpls.2021.698525

Products & Services: Protein Tools

Emerging Insights into Keratin 16 Expression during Metastatic Progression of Breast Cancer

Authors: Maha Elazezy, Sandra Schwentesius, Luisa Stegat, Harriet Wikman, Stefan Werner, Wael Y Mansour, Antonio Virgilio Failla, Sven Peine, Volkmar Müller, Jean Paul Thiery, Majid Ebrahimi Warkiani, Klaus Pantel, Simon A Joosse

Journal: Cancers (Basel)

PubMed ID: 34359774

Doi: 10.3390/cancers13153869

Products & Services: Plasmid DNA Preparation

A head-to-head comparison of the inhibitory activities of 15 peptidomimetic SARS-CoV-2 3CLpro inhibitors

Authors: Subramanyam Vankadara, Yun Xuan Wong, Boping Liu, Yi Yang See, Li Hong Tan, Qian Wen Tan, Gang Wang, Ratna Karuna, Xue Guo, Shu Ting Tan, Jia Yi Fong, Joma Joy, C S Brian Chia

Journal: Bioorg Med Chem Lett

PubMed ID: 34271072

Doi: 10.1016/j.bmcl.2021.128263

Products & Services: Peptide Synthesis

Coatomer protein COPƐ, a novel NS1-interacting protein, promotes the replication of Porcine Parvovirus via attenuation of the production of type I interferon

Authors: Songbiao Chen, Nannan Chen, Bichen Miao, Jiang Peng, Xuezhi Zhang, Caiyi Chen, Xiujuan Zhang, Lingling Chang, Qian Du, Yong Huang, Dewen Tong

Journal: Vet Microbiol

PubMed ID: 34365051

Doi: 10.1016/j.vetmic.2021.109188

Products & Services: Recombinant Proteins

Overlapping Functions of the Paralogous Proteins AtPAP2 and AtPAP9 in

Authors: Renshan Zhang, Xiaoqian Guan, Meijing Yang, Yee-Song Law, Chia Pao Voon, Junran Yan, Feng Sun, Boon Leong Lim

Journal: Int J Mol Sci

PubMed ID: 34298863

Doi: 10.3390/ijms22147243

SARS-CoV-2 Infection in Dogs and Cats from Southern Germany and Northern Italy during the First Wave of the COVID-19 Pandemic

Authors: Julia Klaus, Eric Zini, Katrin Hartmann, Herman Egberink, Anja Kipar, Michèle Bergmann, Carlo Palizzotto, Shan Zhao, Francesco Rossi, Vittoria Franco, Federico Porporato, Regina Hofmann-Lehmann, Marina L Meli

Journal: Viruses

PubMed ID: 34452319

Doi: 10.3390/v13081453

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RNA Splicing Factors SRRM3 and SRRM4 Distinguish Molecular Phenotypes of Castration-Resistant Neuroendocrine Prostate Cancer

Authors: Mark P Labrecque, Lisha G Brown, Ilsa M Coleman, Bryce Lakely, Nicholas J Brady, John K Lee, Holly M Nguyen, Dapei Li, Brian Hanratty, Michael C Haffner, David S Rickman, Lawrence D True, Daniel W Lin, Hung-Ming Lam, Joshi J Alumkal, Eva Corey, Peter S Nelson, Colm Morrissey

Journal: Cancer Res

PubMed ID: 34312180

Doi: 10.1158/0008-5472.CAN-21-0307

Products & Services: PCR Cloning and Subcloning

Membranotropic and biological activities of the membrane fusion peptides from SARS-CoV spike glycoprotein: The importance of the complete internal fusion peptide domain

Authors: Luis Guilherme Mansor Basso, Ana Eliza Zeraik, Ana Paula Felizatti, Antonio José Costa-Filho

Journal: Biochim Biophys Acta Biomembr

PubMed ID: 34274319

Doi: 10.1016/j.bbamem.2021.183697

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CDK1 controls CHMP7-dependent nuclear envelope reformation

Authors: Alberto T Gatta, Yolanda Olmos, Caroline L Stoten, Qu Chen, Peter B Rosenthal, Jeremy G Carlton

Journal: Elife

PubMed ID: 34286694

Doi: 10.7554/eLife.59999

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Endomembrane-Targeting Effectors Modulate PAMP Triggered Immune Responses in Plants

Authors: Md Musharaf Hossain, Edel Pérez-López, Christopher D Todd, Yangdou Wei, Peta C Bonham-Smith

Journal: Front Microbiol

PubMed ID: 34276588

Doi: 10.3389/fmicb.2021.651279

Products & Services: PCR and Cloning

ANXA10 promotes melanoma metastasis by suppressing E3 ligase TRIM41-directed PKD1 degradation

Authors: Xuerui Zhang, Zhaoqing Hu, Xinran Wang, Lin Li, Banghui Zhu, Xiaolei Lin, Jing Zhang, Zichun Hua

Journal: Cancer Lett

PubMed ID: 34324862

Doi: 10.1016/j.canlet.2021.07.033

Products & Services: Recombinant Proteins

Neofunctionalisation of the Sli gene leads to self-compatibility and facilitates precision breeding in potato

Authors: Ernst-Jan Eggers, Ate van der Burgt, Sjaak A W van Heusden, Michiel E de Vries, Richard G F Visser, Christian W B Bachem, Pim Lindhout

Journal: Nat Commun

PubMed ID: 34230471

Doi: 10.1038/s41467-021-24267-6

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Targeting TRAF3IP2 alleviates high glucose-induced cardiomyocyte inflammation and apoptosis

Authors: Jing Wei, Tao Yan, Yuanhong Liang

Journal: Drug Dev Res

PubMed ID: 34260107

Doi: 10.1002/ddr.21856

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Differential Serotonin Uptake Mechanisms at the Human Maternal-Fetal Interface

Authors: Petra Baković, Maja Kesić, Maja Perić, Ivona Bečeheli, Marina Horvatiček, Meekha George, Lipa Čičin-Šain, Gernot Desoye, Christian Wadsack, Ute Panzenboeck, Jasminka Štefulj

Journal: Int J Mol Sci

PubMed ID: 34360573

Doi: 10.3390/ijms22157807

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Nanopore Sequencing Accurately Identifies the Cisplatin Adduct on DNA

Authors: Fubo Ma, Shuanghong Yan, Jinyue Zhang, Yu Wang, Liying Wang, Yuqin Wang, Shanyu Zhang, Xiaoyu Du, Panke Zhang, Hong-Yuan Chen, and Shuo Huang

Journal: ACS Sensors

PubMed ID: 34319692

Doi: doi.org/10.1021/acssensors.1c01212

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Mapping Potential Engineering Sites of Mycobacterium smegmatis porin A (MspA) to Form a Nanoreactor

Authors: Jinyue Zhang, Jiao Cao, Wendong Jia, Shanyu Zhang, Shuanghong Yan, Yuqin Wang, Panke Zhang, Hong-Yuan Chen, Wenfei Li, Shuo Huang

Journal: ACS Sens.

PubMed ID: 34107684

Doi: 10.1021/acssensors.1c00792

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A Live-Attenuated Zika Virus Vaccine with High Production Capacity Confers Effective Protection in Neonatal Mice

Authors: Xianmiao Ye, Xinglong Liu, Tao Shu, Weiqi Deng, Min Liao, Yali Zheng, Xuehua Zheng, Xiaoyan Zhang, Ting Li, Wenxia Fan, Linbing Qu, Ling Chen, Feng Li, Liqiang Feng

Journal: J Virol.

PubMed ID: 33910950

Doi: 10.1128/JVI.00383-21

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Evaluation of Benzylpenicillin as an Internal Standard for Measurement of Piperacillin Bone Concentrations via Microdialysis

Authors: Martin Bruun Knudsen, Mats Bue, Louise L Pontoppidan, Magnus A Hvistendahl, Kjeld S?balle, Maiken Stilling, Pelle Hanberg

Journal: J Pharm Sci

PubMed ID: 34102200

Doi: 10.1016/j.xphs.2021.06.008

Products & Services: Mammalian Expression

Versatile and efficient in vivo genome editing with compact Streptococcus pasteurianus Cas9

Authors: Zhiquan Liu, Siyu Chen, Wanhua xie, Yuning Song, Jinze Li, Liangxue Lai, Zhanjun Li

Journal: Molecular Therapy

Doi: doi.org/10.1016/j.ymthe.2021.06.013

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Structural basis of substrate recognition and translocation by human ABCA4

Authors: Tian Xie， Zike Zhang, Qi Fang, Bowen Du& Xin Gong

Journal: Nature Communications

PubMed ID: 34158497

Doi: doi.org/10.1038/s41467-021-24194-6

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LncRSPH9-4 Facilitates Meningitic Escherichia coli-Caused Blood-Brain Barrier Disruption via miR-17-5p/MMP3 Axis

Authors: Bojie Xu , Ruicheng Yang, Jiyang Fu, Bo Yang, Jiaqi Chen , Chen Tan, Huanchun Chen and Xiangru Wang

Journal: International Journal of Molecular Sciences

PubMed ID: 34198485

Doi: 10.3390/ijms22126343

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Peptides affecting outer membrane lipid asymmetry (MlaA-OmpC/F) system reduce avian pathogenic (APEC) colonization in chickens

Authors: Dipak Kathayat, Gary Closs, Yosra A Helmy, Dhanashree Lokesh, Sochina Ranjit, Gireesh Rajashekara

Journal: Appl Environ Microbiol

PubMed ID: 34132592

Doi: 10.1128/AEM.00567-21

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Metformin-Inducible Small Heterodimer Partner Interacting Leucine Zipper Protein Ameliorates Intestinal Inflammation

Authors: SeungCheon Yang, Jin-Sil Park, Sun-Hee Hwang, Keun-Hyung Cho, Hyun Sik Na, JeongWon Choi, Jooyeon Jhun, Seung-Jun Kim, Bo-In Lee, Sung-Hwan Park, Mi-La Cho

Journal: Front Immunol

PubMed ID: 34211461

Doi: 10.3389/fimmu.2021.652709

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Histone demethylase PHF8 promotes cell growth and metastasis of non-small-cell lung cancer through activating Wnt/β-catenin signaling pathway

Authors: Yan Hu, Hanshuo Mu, Ying Yang

Journal: Histol Histopathol

PubMed ID: 34100557

Doi: 10.14670/HH-18-349

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LINC00839 Regulates Proliferation, Migration, Invasion, Apoptosis and Glycolysis in Neuroblastoma Cells Through miR-338-3p/GLUT1 Axis

Authors: Lixia Yang, Liangyan Pei, Jilong Yi

Journal: Neuropsychiatr Dis Treat

PubMed ID: 34188473

Doi: 10.2147/NDT.S309467

Products & Services: Gene Synthesis

Humoral and cellular immune responses against SARS-CoV-2 variants and human coronaviruses after single BNT162b2 vaccination

Authors: Metodi V Stankov, Anne Cossmann, Agnes Bonifacius, Alexandra Dopfer-Jablonka, Gema Morillas Ramos, Nina Gödecke, Anna Zychlinsky Scharff, Christine Happle, Anna-Lena Boeck, Anh Thu Tran, Isabell Pink, Marius M Hoeper, Rainer Blasczyk, Martin S Winkler, Inga Nehlmeier, Amy Kempf, Heike Hofmann-Winkler, Markus Hoffmann, Britta Eiz-Vesper, Stefan Pöhlmann, Georg M N Behrens

Journal: Clin Infect Dis

PubMed ID: 34134134

Doi: 10.1093/cid/ciab555

Products & Services: Proteins, Expression, Isolation and Analysis

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