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Serological survey of antibodies against SARS-CoV-2 in dogs and cats, Thailand

Authors: Kitikhun Udom, Waleemas Jairak, Ekkapat Chamsai, Kamonpan Charoenkul, Supanat Boonyapisitsopa, Napawan Bunpapong, Navapon Techakriengkrai, Alongkorn Amonsin

Journal: Transbound Emerg Dis

PubMed ID: 34180590

Doi: 10.1111/tbed.14208

Products & Services: Protein Reagents and Products

Design and in silico analysis of a whole-cell biosensor able to kill methicillin-resistant Staphylococcus aureus

Authors: Diego Francisco Benítez-Chao, Francisco de Jesús Balderas-Cisneros, Angel León-Buitimea, José Rubén Morones-Ramírez

Journal: Biotechnol Appl Biochem

PubMed ID: 34081352

Doi: 10.1002/bab.2210

Products & Services: Gene Synthesis

Activation of Protein Tyrosine Phosphatase Receptor Type γ Suppresses Mechanisms of Adhesion and Survival in Chronic Lymphocytic Leukemia Cells

Authors: Alessio Montresor, Lara Toffali, Laura Fumagalli, Gabriela Constantin, Antonella Rigo, Isacco Ferrarini, Fabrizio Vinante, Carlo Laudanna

Journal: J Immunol

PubMed ID: 34162728

Doi: 10.4049/jimmunol.2001462

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In Search of the SARS-CoV-2 Protection Correlate: Head-to-Head Comparison of Two Quantitative S1 Assays in Pre-characterized Oligo-/Asymptomatic Patients

Authors: Raquel Rubio-Acero, Noemi Castelletti, Volker Fingerle, Laura Olbrich, Abhishek Bakuli, Roman Wölfel, Philipp Girl, Katharina Müller, Simon Jochum, Matthias Strobl, Michael Hoelscher, Andreas Wieser

Journal: Infect Dis Ther

PubMed ID: 34155471

Doi: 10.1007/s40121-021-00475-x

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Circular RNA CDR1as Inhibits the Metastasis of Gastric Cancer through Targeting miR-876-5p/GNG7 Axis

Authors: Jiajia Jiang, Rong Li, Junyi Wang, Jie Hou, Hui Qian, Wenrong Xu

Journal: Gastroenterol Res Pract

PubMed ID: 34221006

Doi: 10.1155/2021/5583029

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CRKL is a critical target of Hh-GLI2 pathway in lung adenocarcinoma

Authors: Xiaoming Liu, Yan Hu, Bentong Yu, Kai Peng, Xin Gan

Journal: J Cell Mol Med

PubMed ID: 34076957

Doi: 10.1111/jcmm.16592

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A Protective Role of FAM13A in Human Airway Epithelial Cells Upon Exposure to Cigarette Smoke Extract

Authors: Qing Chen, Maaike de Vries, Kingsley Okechukwu Nwozor, Jacobien A Noordhoek, Corry-Anke Brandsma, H Marike Boezen, Irene H Heijink

Journal: Front Physiol

PubMed ID: 34163376

Doi: 10.3389/fphys.2021.690936

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A novel transcriptional complex on the VE-cadherin promoter regulated the downregulation of VE-cadherin in the Down Syndrome Candidate Region 1 isoform 1L-mediated angiogenesis

Authors: Shiqiang Hou, Gengming Niu, Xin Liu, Pierre M Bourbon, Dongmei Zhang, Pengfei Cui, Kevin Zhao, Dezheng Zhao, Huiyan Zeng

Journal: Microvasc Res

PubMed ID: 34146582

Doi: 10.1016/j.mvr.2021.104209

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Secondary Structure of the Novel Myosin Binding Domain WYR and Implications within Myosin Structure

Authors: Lynda M Menard, Neil B Wood, Jim O Vigoreaux

Journal: Biology (Basel)

PubMed ID: 34209926

Doi: 10.3390/biology10070603

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Identification of ACE2 modifiers by CRISPR screening

Authors: Emily J Sherman, Carmen Mirabelli, Vi T Tang, Taslima G Khan, Andrew A Kennedy, Sarah E Graham, Cristen J Willer, Andrew W Tai, Jonathan Z Sexton, Christiane E Wobus, Brian T Emmer

Journal: biorxiv

PubMed ID: 34127970

Doi: 10.1101/2021.06.10.447768

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Nucleoprotein (P40) Binding to 5HT2C Receptors (5HT2CR) is the Key Point in the Pathogenesis of BoDV-1-Infected Hosts

Authors: Yuanxin Li, Lixin Wang, Xueni Liu, Ying Huang, Xiaomei Li, Hong He, Xiaoyan Xu, Yujie Guo, Qi Li, Dan Zhu, Xingyu Wang, Haiyang Wang, Wenwen Li, Dan Li, Peng Xie

Journal: Neurochem Res

PubMed ID: 34165668

Doi: 10.1007/s11064-021-03385-z

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Large-Scale Oligonucleotide Synthesis for Whole-Genome Synthesis and Data Storage: Challenges and Opportunities

Authors: Li-Fu Song, Zheng-Hua Deng, Zi-Yi Gong, Lu-Lu Li, Bing-Zhi Li

Journal: Front Bioeng Biotechnol

PubMed ID: 34239862

Doi: 10.3389/fbioe.2021.689797

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Programming Cells by Multicopy Chromosomal Integration Using CRISPR-Associated Transposases

Authors: Yiwen Zhang, Jiawei Yang, Siqi Yang, Jieze Zhang, Jun Chen, Rongsheng Tao, Yu Jiang, Junjie Yang, Sheng Yang

Journal: CRISPR J

PubMed ID: 34152213

Doi: 10.1089/crispr.2021.0018

Products & Services: Gene Synthesis

Comparing Results of Five SARS-CoV-2 Antibody Assays Before and After the First Dose of ChAdOx1 nCoV-19 Vaccine among Health Care Workers

Authors: Seri Jeong, Nuri Lee, Su Kyung Lee, Eun-Jung Cho, Jungwon Hyun, Min-Jeong Park, Wonkeun Song, Eun Ju Jung, Heungjeong Woo, Yu Bin Seo, Jin Ju Park, Hyun Soo Kim

Journal: J Clin Microbiol

PubMed ID: 34191577

Doi: 10.1128/JCM.01105-21

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Absence of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies in stray cats

Authors: Angelica Stranieri, Stefania Lauzi, Alessia Giordano, Luigi Galimberti, Gabriele Ratti, Nicola Decaro, Federica Brioschi, Davide Lelli, Silvia Gabba, Ndiana Linda Amarachi, Eleonora Lorusso, Ana Moreno, Tiziana Trogu, Saverio Paltrinieri

Journal: Transbound Emerg Dis

PubMed ID: 34170624

Doi: 10.1111/tbed.14200

Products & Services: Gene Synthesis

Model infant biscuits release the opioid-acting peptides milk β-casomorphins and gluten exorphins after in vitro gastrointestinal digestion

Authors: Valentina Pica, Milda Stuknytė, Fabio Masotti, Ivano De Noni, Stefano Cattaneo

Journal: Food Chem

PubMed ID: 34118509

Doi: 10.1016/j.foodchem.2021.130262

Products & Services: Peptide Synthesis

De novo biosynthesis of -arabinosylated flavones by utilization of rice -glycosyltransferases

Authors: Zhuo Chen, Yuwei Sun, Guangyi Wang, Ying Zhang, Qian Zhang, Yulian Zhang, Jianhua Li, Yong Wang

Journal: Bioresour Bioprocess

PubMed ID: 34150466

Doi: 10.1186/s40643-021-00404-3

Products & Services: Gene Synthesis

ptFVa ( Venom-Derived Factor Va) Retains Structural Integrity Following Proteolysis by Activated Protein C

Authors: Mark Schreuder, Xiaosong Liu, Ka Lei Cheung, Pieter H Reitsma, Gerry A F Nicolaes, Mettine H A Bos

Journal: Arterioscler Thromb Vasc Biol

PubMed ID: 34162230

Doi: 10.1161/ATVBAHA.121.316038

Products & Services: Gene Synthesis

Evaluation of a Surrogate ELISA- Based Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) cPass Neutralization Antibody Detection Assay and Correlation with IgG Commercial Serology Assays

Authors: Vijayalakshmi Nandakumar, Tracie Profaizer, Bucky K Lozier, Marc G Elgort, Erin T Larragoite, Elizabeth S C P Williams, Antonio Solis-Leal, J Brandon Lopez, Bradford K Berges, Vicente Planelles, Jenna Rychert, Patricia R Slev, Julio C Delgado

Journal: Arch Pathol Lab Med

PubMed ID: 34181714

Doi: 10.5858/arpa.2021-0213-SA

Products & Services: Protein Reagents and Products

Evaluating a new mixed-mode resin Diamond MMC Mustang using Capto MMC ImpRes as a benchmark

Authors: Shengwei Zhang, Yan Wan, Jiwei Duan, Yifeng Li

Journal: Protein Expr Purif

PubMed ID: 34147604

Doi: 10.1016/j.pep.2021.105930

Products & Services: Nucleic Acid Purification & Analysis

Focused peptide library screening as a route to a superior affinity ligand for antibody purification

Authors: Krištof Bozovičar, Barbara Jenko Bizjan, Anže Meden, Jernej Kovač, Tomaž Bratkovič

Journal: Sci Rep

PubMed ID: 34079028

Doi: 10.1038/s41598-021-91208-0

Products & Services: Codon Optimization

Metaproteomic Discovery and Characterization of a Novel Lipolytic Enzyme From an Indian Hot Spring

Authors: Dennis Sander, Yanfei Yu, Premankur Sukul, Sina Schäkermann, Julia E Bandow, Trinetra Mukherjee, Subhra Kanti Mukhopadhyay, Lars I Leichert

Journal: Front Microbiol

PubMed ID: 34149658

Doi: 10.3389/fmicb.2021.672727

Products & Services: Gene Synthesis

The three-way junction structure of the HIV-1 PBS-segment binds host enzyme important for viral infectivity

Authors: Zhenwei Song, Thomas Gremminger, Gatikrushna Singh, Yi Cheng, Jun Li, Liming Qiu, Juan Ji, Margaret J Lange, Xiaobing Zuo, Shi-Jie Chen, Xiaoqin Zou, Kathleen Boris-Lawrie, Xiao Heng

Journal: Nucleic Acids Res

PubMed ID: 33978756

Doi: 10.1093/nar/gkab342

Products & Services: GenParts™ DNA Fragments

The steroid-hormone ecdysone coordinates parallel pupariation neuromotor and morphogenetic subprograms via epidermis-to-neuron Dilp8-Lgr3 signal induction

Authors: Fabiana Heredia, Yanel Volonté, Joana Pereirinha, Magdalena Fernandez-Acosta, Andreia P Casimiro, Cláudia G Belém, Filipe Viegas, Kohtaro Tanaka, Juliane Menezes, Maite Arana, Gisele A Cardoso, André Macedo, Malwina Kotowicz, Facundo H Prado Spalm, Marcos J Dibo, Raquel D Monfardini, Tatiana T Torres, César S Mendes, Andres Garelli, Alisson M Gontijo

Journal: Nat Commun

PubMed ID: 34099654

Doi: 10.1038/s41467-021-23218-5

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Entropic pressure controls the oligomerization of the Vibrio cholerae ParD2 antitoxin

Authors: Gabriela Garcia-Rodriguez, Yana Girardin, Alexander N Volkov, Ranjan Kumar Singh, Gopinath Muruganandam, Jeroen Van Dyck, Frank Sobott, Wim Versées, Daniel Charlier, Remy Loris

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 34196617

Doi: 10.1107/S2059798321004873

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Norovirus VPg Binds RNA through a Conserved N-Terminal K/R Basic Patch

Authors: Alice M McSweeney, Vivienne L Young, Vernon K Ward

Journal: Viruses

PubMed ID: 34209211

Doi: 10.3390/v13071282

Products & Services: Bacterial Expression

Contingency and chance erase necessity in the experimental evolution of ancestral proteins

Authors: Victoria Cochran Xie, Jinyue Pu, Brian Ph Metzger, Joseph W Thornton, Bryan C Dickinson

Journal: Elife

PubMed ID: 34061027

Doi: 10.7554/eLife.67336

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Immunogenic potential of DNA vaccine candidate, ZyCoV-D against SARS-CoV-2 in animal models

Authors: Ayan Dey, T M Chozhavel Rajanathan, Harish Chandra, Hari P R Pericherla, Sanjeev Kumar, Huzaifa S Choonia, Mayank Bajpai, Arun K Singh, Anuradha Sinha, Gurwinder Saini, Parth Dalal, Sarosh Vandriwala, Mohammed A Raheem, Rupesh D Divate, Neelam L Navlani, Vibhuti Sharma, Aashini Parikh, Siva Prasath, M Sankar Rao, Kapil Maithal

Journal: Vaccine

PubMed ID: 34120764

Doi: 10.1016/j.vaccine.2021.05.098

Products & Services: Proteins, Expression, Isolation and Analysis

Upregulated Tie2 expression in plasma: a potential non-invasive biomarker for the diagnosis of breast cancer

Authors: Qingzhu Song, Fenglan Zhang, Tian Yuan, Yulong Wei

Journal: Eur Cytokine Netw

PubMed ID: 34240713

Doi: 10.1684/ecn.2021.0468

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Pro-resolving lipid mediator lipoxin A attenuates neuro-inflammation by modulating T cell responses and modifies the spinal cord lipidome

Authors: Claudio Derada Troletti, Gaby Enzmann, Valerio Chiurchiù, Alwin Kamermans, Silvia Martina Tietz, Paul C Norris, Neda Haghayegh Jahromi, Alessandro Leuti, Susanne M A van der Pol, Marijn Schouten, Charles N Serhan, Helga E de Vries, Britta Engelhardt, Gijs Kooij

Journal: Cell Rep

PubMed ID: 34077725

Doi: 10.1016/j.celrep.2021.109201

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The HGR motif is the antiangiogenic determinant of vasoinhibin: implications for a therapeutic orally active oligopeptide

Authors: Juan Pablo Robles, Magdalena Zamora, Lourdes Siqueiros-Marquez, Elva Adan-Castro, Gabriela Ramirez-Hernandez, Francisco Freinet Nuñez, Fernando Lopez-Casillas, Robert P Millar, Thomas Bertsch, Gonzalo Martínez de la Escalera, Jakob Triebel, Carmen Clapp

Journal: Angiogenesis

PubMed ID: 34097181

Doi: 10.1007/s10456-021-09800-x

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Metabolic radiolabeling and in vivo PET imaging of cytotoxic T lymphocytes to guide combination adoptive cell transfer cancer therapy

Authors: Dehua Lu, Yanpu Wang, Ting Zhang, Feng Wang, Kui Li, Shixin Zhou, Hua Zhu, Zhi Yang, Zhaofei Liu

Journal: J Nanobiotechnology

PubMed ID: 34112200

Doi: 10.1186/s12951-021-00924-2

Products & Services: Recombinant Proteins

The Effect of Interferons on Presentation of Defective Ribosomal Products as HLA Peptides

Authors: Liran Komov, Dganit Melamed Kadosh, Eilon Barnea, Arie Admon

Journal: Mol Cell Proteomics

PubMed ID: 34087483

Doi: 10.1016/j.mcpro.2021.100105

Products & Services: Proteins, Expression, Isolation and Analysis

Expression of miR-195 and its target gene Bcl-2 in human intervertebral disc degeneration and their effects on nucleus pulposus cell apoptosis

Authors: Xue-Lin Lin, Zhao-Yun Zheng, Qing-Shan Zhang, Zhen Zhang, You-Zhi An

Journal: J Orthop Surg Res

PubMed ID: 34183039

Doi: 10.1186/s13018-021-02538-8

Products & Services: Custom DNA/RNA Oligos

LEO1 is a partner for Cockayne syndrome protein B (CSB) in response to transcription-blocking DNA damage

Authors: Vinod Tiwari, Tomasz Kulikowicz, David M Wilson, Vilhelm A Bohr

Journal: Nucleic Acids Res

PubMed ID: 34096589

Doi: 10.1093/nar/gkab458

Products & Services: Proteins, Expression, Isolation and Analysis

Temporal induction of Lhx8 by optogenetic control system for efficient bone regeneration

Authors: Delan Huang, Runze Li, Jianhan Ren, Haotian Luo, Weicai Wang, Chen Zhou

Journal: Stem Cell Res Ther

PubMed ID: 34112263

Doi: 10.1186/s13287-021-02412-8

Products & Services: Plasmid DNA Preparation

Targeted Radionuclide Therapy Using Auger Electron Emitters: The Quest for the Right Vector and the Right Radionuclide

Authors: Malick Bio Idrissou, Alexandre Pichard, Bryan Tee, Tibor Kibedi, Sophie Poty, Jean-Pierre Pouget

Journal: Pharmaceutics

PubMed ID: 34209637

Doi: 10.3390/pharmaceutics13070980

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A Novel Plasmid DNA-Based Foot and Mouth Disease Virus Minigenome for Intracytoplasmic mRNA Production

Authors: Ploypailin Semkum, Challika Kaewborisuth, Nattarat Thangthamniyom, Sirin Theerawatanasirikul, Chalermpol Lekcharoensuk, Payuda Hansoongnern, Pongrama Ramasoota, Porntippa Lekcharoensuk

Journal: Viruses

PubMed ID: 34205958

Doi: 10.3390/v13061047

Products & Services: Recombinant Proteins

Proteoform Differentiation using Tandem Trapped Ion Mobility, Electron Capture Dissociation, and ToF Mass Spectrometry

Authors: Kevin Jeanne Dit Fouque, Desmond Kaplan, Valery G Voinov, Frederik H V Holck, Ole N Jensen, Francisco Fernandez-Lima

Journal: Anal Chem

PubMed ID: 34170114

Doi: 10.1021/acs.analchem.1c01735

Products & Services: Recombinant Proteins

Function is more reliable than quantity to follow up the humoral response to the Receptor Binding Domain of SARS- CoV-2 Spike protein after natural infection or COVID-19 vaccination

Authors: Carlos A Sariol, Petraleigh Pantoja, Crisanta Serrano-Collazo, Tiffany Rosa-Arocho, Albersy Armina, Lorna Cruz, E Taylor Stone, Teresa Arana, Consuelo Climent, Gerardo Latoni, Dianne Atehortua, Christina Pabon-Carrero, Amelia K Pinto, James D Brien, Ana M Espino

Journal: medrxiv

PubMed ID: 34100029

Doi: 10.1101/2021.06.02.21257975

Genes encoding putative bicarbonate transporters as a missing molecular link between molt and mineralization in crustaceans

Authors: Shai Abehsera, Shmuel Bentov, Xuguang Li, Simy Weil, Rivka Manor, Shahar Sagi, Shihao Li, Fuhua Li, Isam Khalaila, Eliahu D Aflalo, Amir Sagi

Journal: Sci Rep

PubMed ID: 34083647

Doi: 10.1038/s41598-021-91155-w

Products & Services: Proteins, Expression, Isolation and Analysis

The fidelity of DNA replication, particularly on GC-rich templates, is reduced by defects of the Fe-S cluster in DNA polymerase δ

Authors: Denis A Kiktev, Margaret Dominska, Tony Zhang, Joseph Dahl, Elena I Stepchenkova, Piotr Mieczkowski, Peter M Burgers, Scott Lujan, Adam Burkholder, Thomas A Kunkel, Thomas D Petes

Journal: Nucleic Acids Res

PubMed ID: 34019669

Doi: 10.1093/nar/gkab371

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Impact of Membrane Lipids on UapA and AzgA Transporter Subcellular Localization and Activity in

Authors: Mariangela Dionysopoulou, George Diallinas

Journal: J Fungi (Basel)

PubMed ID: 34203131

Doi: 10.3390/jof7070514

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Impact of CRISPR-Cas9-Based Genome Engineering in Farm Animals

Authors: Parul Singh, Syed Azmal Ali

Journal: Vet Sci

PubMed ID: 34209174

Doi: 10.3390/vetsci8070122

"Resurrected" human-source urate oxidase with high uricolytic activity and stability

Authors: Nan Jiang, Chunqin Xu, Linhan Zhang, Jianhua Chen

Journal: Enzyme Microb Technol

PubMed ID: 34311889

Doi: 10.1016/j.enzmictec.2021.109852

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"Resurrected" human-source urate oxidase with high uricolytic activity and stability

Authors: Nan Jiang, Chunqin Xu, Linhan Zhang, Jianhua Chen

Journal: Enzyme Microb Technol

PubMed ID: 34311889

Doi: 10.1016/j.enzmictec.2021.109852

Products & Services: GenParts™ DNA Fragments

Stabilization of the SARS-CoV-2 Spike Receptor-Binding Domain Using Deep Mutational Scanning and Structure-Based Design

Authors: Daniel Ellis, Natalie Brunette, Katharine H D Crawford, Alexandra C Walls, Minh N Pham, Chengbo Chen, Karla-Luise Herpoldt, Brooke Fiala, Michael Murphy, Deleah Pettie, John C Kraft, Keara D Malone, Mary Jane Navarro, Cassandra Ogohara, Elizabeth Kepl, Rashmi Ravichandran, Claire Sydeman, Maggie Ahlrichs, Max Johnson, Alyssa Blackstone, Lauren Carter, Tyler N Starr, Allison J Greaney, Kelly K Lee, David Veesler, Jesse D Bloom, Neil P King

Journal: Front Immunol

PubMed ID: 34267764

Doi: 10.3389/fimmu.2021.710263

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SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care

Authors: Clemens Gutmann, Kaloyan Takov, Sean A Burnap, Bhawana Singh, Hashim Ali, Konstantinos Theofilatos, Ella Reed, Maria Hasman, Adam Nabeebaccus, Matthew Fish, Mark Jw McPhail, Kevin O'Gallagher, Lukas E Schmidt, Christian Cassel, Marieke Rienks, Xiaoke Yin, Georg Auzinger, Salvatore Napoli, Salma F Mujib, Francesca Trovato, Barnaby Sanderson, Blair Merrick, Umar Niazi, Mansoor Saqi, Konstantina Dimitrakopoulou, Rafael Fernández-Leiro, Silke Braun, Romy Kronstein-Wiedemann, Katie J Doores, Jonathan D Edgeworth, Ajay M Shah, Stefan R Bornstein, Torsten Tonn, Adrian C Hayday, Mauro Giacca, Manu Shankar-Hari, Manuel Mayr

Journal: Nat Commun

PubMed ID: 34099652

Doi: 10.1038/s41467-021-23494-1

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WSX1 act as a tumor suppressor in hepatocellular carcinoma by downregulating neoplastic PD-L1 expression

Authors: Man Wu, Xueqing Xia, Jiemiao Hu, Natalie Wall Fowlkes, Shulin Li

Journal: Nat Commun

PubMed ID: 34108491

Doi: 10.1038/s41467-021-23864-9

Products & Services: Plasmid DNA Preparation

Mutation-induced dimerization of transforming growth factor-β-induced protein (TGFBIp) may drive protein aggregation in granular corneal dystrophy

Authors: Nadia Sukusu Nielsen, Trine A F Gadeberg, Ebbe Toftgaard Poulsen, Seandean Lykke Harwood, Christian E Weberskov, Jan Skov Pedersen, Gregers R Andersen, Jan J Enghild

Journal: J Biol Chem

PubMed ID: 34097874

Doi: 10.1016/j.jbc.2021.100858

Products & Services: Mammalian Expression

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