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Synchrotron Radiation-Fourier Transformed Infrared microspectroscopy (μSR-FTIR) reveals multiple metabolism alterations in microalgae induced by cadmium and mercury
Authors: Ángel Barón-Sola, Margarita Toledo-Basantes, María Arana-Gandía, Flor Martínez, Cristina Ortega-Villasante, Tanja Dučić, Ibraheem Yousef, Luis E Hernández
Journal: J Hazard Mater
PubMed ID: 34214848
Doi: 10.1016/j.jhazmat.2021.126502
Evaluation of Heterologous Biosynthetic Pathways for Methanol-Based 5-Aminovalerate Production by Thermophilic
Authors: Luciana Fernandes Brito, Marta Irla, Ingemar Nærdal, Simone Balzer Le, Baudoin Delépine, Stéphanie Heux, Trygve Brautaset
Journal: Front Bioeng Biotechnol
PubMed ID: 34262896
Doi: 10.3389/fbioe.2021.686319
Products & Services: Plasmid DNA Preparation   
SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells
Authors: Jae Hyung Jung, Min-Seok Rha, Moa Sa, Hee Kyoung Choi, Ji Hoon Jeon, Hyeri Seok, Dae Won Park, Su-Hyung Park, Hye Won Jeong, Won Suk Choi, Eui-Cheol Shin
Journal: Nat Commun
PubMed ID: 34193870
Doi: 10.1038/s41467-021-24377-1
Functional differences between TSHR alleles associate with variation in spawning season in Atlantic herring
Authors: Junfeng Chen, Huijuan Bi, Mats E Pettersson, Daiki X Sato, Angela P Fuentes-Pardo, Chunheng Mo, Shady Younis, Ola Wallerman, Patric Jern, Gregorio Molés, Ana Gómez, Gunnar Kleinau, Patrick Scheerer, Leif Andersson
Journal: Commun Biol
PubMed ID: 34172814
Doi: 10.1038/s42003-021-02307-7
Products & Services: Custom Vector Construction   
Comparative Molecular Characterization of Novel and Known Piscine Toti-Like Viruses
Authors: Liv Sandlund, Sunil K Mor, Vikash K Singh, Soumesh K Padhi, Nicholas B D Phelps, Stian Nylund, Aase B Mikalsen
Journal: Viruses
PubMed ID: 34205093
Doi: 10.3390/v13061063
Products & Services: Gene Synthesis   
Validating TDP1 as an Inhibition Target for the Development of Chemosensitizers for Camptothecin-Based Chemotherapy Drugs
Authors: Euphemia Leung, Jinal Patel, Jennifer A Hollywood, Ayesha Zafar, Petr Tomek, David Barker, Lisa I Pilkington, Michelle van Rensburg, Ries J Langley, Nuala A Helsby, Christopher J Squire, Bruce C Baguley, William A Denny, Jóhannes Reynisson, Ivanhoe K H Leung
Journal: Oncol Ther
PubMed ID: 34159519
Doi: 10.1007/s40487-021-00158-0
Products & Services: Mammalian Expression   
Tanshinones induce tumor cell apoptosis via directly targeting FHIT
Authors: Xianglian Zhou, Yuting Pan, Yue Wang, Bojun Wang, Yu Yan, Yi Qu, Xisong Ke
Journal: Sci Rep
PubMed ID: 34108553
Doi: 10.1038/s41598-021-91708-z
Products & Services: Mammalian Expression   
Microbiota-related effects of prebiotic fibres in lipopolysaccharide-induced endotoxemic mice: short chain fatty acid production and gut commensal translocation
Authors: Songtao Fan, Zhihong Zhang, Yadong Zhong, Chang Li, Xiaojun Huang, Fang Geng, Shaoping Nie
Journal: Food Funct
PubMed ID: 34180493
Doi: 10.1039/d1fo00410g
Products & Services: Monoclonal Antibody Services   
Atherosclerosis-associated hepatic secretion of VLDL but not PCSK9 is dependent on cargo receptor protein Surf4
Authors: Bingxiang Wang, Yishi Shen, Lei Zhai, Xiaodan Xia, Hong-Mei Gu, Maggie Wang, Yongfang Zhao, Xiaole Chang, Adekunle Alabi, Sijie Xing, Shijun Deng, Boyan Liu, Guiqing Wang, Shucun Qin, Da-Wei Zhang
Journal: J Lipid Res
PubMed ID: 34118252
Doi: 10.1016/j.jlr.2021.100091
Products & Services: Catalog Peptides   
Canonical T cell receptor docking on peptide-MHC is essential for T cell signaling
Authors: Pirooz Zareie, Christopher Szeto, Carine Farenc, Sachith D Gunasinghe, Elizabeth M Kolawole, Angela Nguyen, Chantelle Blyth, Xavier Y X Sng, Jasmine Li, Claerwen M Jones, Alex J Fulcher, Jesica R Jacobs, Qianru Wei, Lukasz Wojciech, Jan Petersen, Nicholas R J Gascoigne, Brian D Evavold, Katharina Gaus, Stephanie Gras, Jamie Rossjohn, Nicole L La Gruta
Journal: Science
PubMed ID: 34083463
Doi: 10.1126/science.abe9124
Products & Services: Plasmid DNA Preparation   
Phenolic compounds disrupt spike-mediated receptor-binding and entry of SARS-CoV-2 pseudo-virions
Authors: Anna Goc, Waldemar Sumera, Matthias Rath, Aleksandra Niedzwiecki
Journal: PLoS ONE
PubMed ID: 34138966
Doi: 10.1371/journal.pone.0253489
Products & Services: Protein Reagents and Products   
Double-faced role of Bcl-2-associated athanogene 7 in plant-Phytophthora interaction
Authors: Yang Zhou, Kun Yang, Ming Cheng, Yang Cheng, Yurong Li, Gan Ai, Tian Bai, Ruofei Xu, Weiwei Duan, Hao Peng, Xiaobo Li, Ai Xia, Yuanchao Wang, Maofeng Jing, Daolong Dou, Marty B Dickman
Journal: J Exp Bot
PubMed ID: 34195821
Doi: 10.1093/jxb/erab252
Products & Services: Gene Synthesis   
Impact of copper treatment on phenylpropanoid biosynthesis in adventitious root culture of L
Authors: Yun Ji Park, Nam Su Kim, Ramaraj Sathasivam, Yong Suk Chung, Sang Un Park
Journal: Prep Biochem Biotechnol
PubMed ID: 34154516
Doi: 10.1080/10826068.2021.1934697
Products & Services: Gene Synthesis   
A Covalently Crosslinked Ink for Multimaterials Drop-on-Demand 3D Bioprinting of 3D Cell Cultures
Authors: Robert H Utama, Vincent T G Tan, Kristel C Tjandra, Andrew Sexton, Duyen H T Nguyen, Aidan P O'Mahony, Eric Y Du, Peilin Tian, Julio C C Ribeiro, Maria Kavallaris, J Justin Gooding
Journal: Macromol Biosci
PubMed ID: 34173320
Doi: 10.1002/mabi.202100125
Nanoparticle-based fluorescence probe for detection of NF-κB transcription factor in single cell via steric hindrance
Authors: Yuedi Ding, Zhenqiang Fan, Bo Yao, Dong Xu, Minhao Xie, Kai Zhang
Journal: Mikrochim Acta
PubMed ID: 34106343
Doi: 10.1007/s00604-021-04878-y
Products & Services: Gene Synthesis   
MMP2 and TLRs modulate immune responses in the tumor microenvironment
Authors: Luciana R Muniz-Bongers, Christopher B McClain, Mansi Saxena, Gerold Bongers, Miriam Merad, Nina Bhardwaj
Journal: JCI Insight
PubMed ID: 34032639
Doi: 10.1172/jci.insight.144913
Products & Services: Gene Synthesis   
Rational selection of hidden epitopes for a molecularly imprinted electrochemical sensor in the recognition of heat-denatured dengue NS1 protein
Authors: Matheus Siqueira Silva, Ana Patricia Moreira Tavares, Luiz Felipe Leomil Coelho, Lígia Ely Morganti Ferreira Dias, Rosa Maria Chura-Chambi, Flávio Guimarães da Fonseca, Maria Goreti Ferreira Sales, Eduardo Costa Figueiredo
Journal: Biosens Bioelectron
PubMed ID: 34144470
Doi: 10.1016/j.bios.2021.113419
Products & Services: Peptide Synthesis   
Third-Generation Anti-CD47-Specific CAR-T Cells Effectively Kill Cancer Cells and Reduce the Genes Expression in Lung Cancer Cell Metastasis
Authors: Huyen Thi La, Dao Bich Thi Tran, Hai Manh Tran, Linh Trong Nguyen
Journal: J Immunol Res
PubMed ID: 34189144
Doi: 10.1155/2021/5575260
Products & Services: Gene Synthesis   
Biochemical characterization of a recombinant acid phosphatase from Acinetobacter baumannii
Authors: Elizabeth Smiley-Moreno, Douglas Smith, Jieh-Juen Yu, Phuong Cao, Bernard P Arulanandam, James P Chambers
Journal: PLoS ONE
PubMed ID: 34077475
Doi: 10.1371/journal.pone.0252377
Products & Services: Gene Synthesis   
Anti-Spike Protein Assays to Determine SARS-CoV-2 Antibody Levels: a Head-to-Head Comparison of Five Quantitative Assays
Authors: Thomas Perkmann, Nicole Perkmann-Nagele, Thomas Koller, Patrick Mucher, Astrid Radakovics, Rodrig Marculescu, Michael Wolzt, Oswald F Wagner, Christoph J Binder, Helmuth Haslacher
Journal: Microbiol Spectr
PubMed ID: 34190591
Doi: 10.1128/Spectrum.00247-21
Products & Services: Recombinant Proteins   
miR-139-5p mediates the palmitate-induced inhibition of insulin secretion by targeting neuronal pentraxin 1 in INS-1 cells
Authors: Kai Zhang, Yijian Zhang, Cheng Chen, Yuexing Yuan, Xiaotian Jiang, Xiangjiang Yuan, Yao Wang
Journal: Acta Biochim Biophys Sin (Shanghai)
PubMed ID: 34142698
Doi: 10.1093/abbs/gmab082
Products & Services: Mutagenesis Services   
Low-dose rAAV-mediated inhibition of VEGF can treat neovascular pathologies without inducing retinal vasculitis
Authors: Shun-Yun Cheng, Yongwen Luo, Anneliese Malachi, Jihye Ko, Qin Su, Jun Xie, Bo Tian, Haijiang Lin, Xiao Ke, Qiang Zheng, Phillip W L Tai, Guangping Gao, Claudio Punzo
Journal: Hum Gene Ther
PubMed ID: 34182803
Doi: 10.1089/hum.2021.132
Products & Services: Recombinant Proteins   
Structural insights into the interaction of papain-like protease 2 from the alphacoronavirus porcine epidemic diarrhea virus and ubiquitin
Authors: Ian A Durie, John V Dzimianski, Courtney M Daczkowski, Jack McGuire, Kay Faaberg, Scott D Pegan
Journal: Acta Crystallogr D Struct Biol
PubMed ID: 34196620
Doi: 10.1107/S205979832100509X
Products & Services: Custom Vector Construction   
Silencing of ANGPTL8 Alleviates Insulin Resistance in Trophoblast Cells
Authors: Yu Bai, Qiang Du, Le Zhang, Ling Li, Nana Wang, Bo Wu, Ping Li, Ling Li
Journal: Front Endocrinol (Lausanne)
PubMed ID: 34163433
Doi: 10.3389/fendo.2021.635321
Products & Services: Catalog Antibody   
An optimized and robust SARS-CoV-2 pseudovirus system for viral entry research
Authors: Peng Yang, Yang Yang, Yuming Wu, Cong Huang, Yanlei Ding, Xuejun Wang, Shengqi Wang
Journal: J Virol Methods
PubMed ID: 34182038
Doi: 10.1016/j.jviromet.2021.114221
Products & Services: Codon Optimization   
The lncRNA PVT1 regulates autophagy in regulatory T cells to suppress heart transplant rejection in mice by targeting miR-146a
Authors: Jian Lu, Xiaodong Wang, Baotong Zhang, Peiyuan Li, Xuezhi Du, Feng Qi
Journal: Cell Immunol
PubMed ID: 34214903
Doi: 10.1016/j.cellimm.2021.104400
Products & Services: Custom Vector Construction   
Proline-arginine poly-dipeptide encoded by the C9orf72 repeat expansion inhibits adenosine deaminase acting on RNA
Authors: Hiroaki Suzuki, Masaaki Matsuoka
Journal: J Neurochem
PubMed ID: 34081786
Doi: 10.1111/jnc.15445
Products & Services: Gene Synthesis   
PU1 Mimic Synthetic Peptides Selectively Bind with GATA-1 and Allow c-Jun PU1 Binding to Enhance Myelopoiesis
Authors: Pawan Kumar Raghav, Gurudutta Gangenahalli
Journal: Int J Nanomedicine
PubMed ID: 34113102
Doi: 10.2147/IJN.S303235
Products & Services: Gene Synthesis   
Tin Mesoporphyrin Selectively Reduces Non-Small-Cell Lung Cancer Cell Line A549 Proliferation by Interfering with Heme Oxygenase and Glutathione Systems
Authors: Valeria Sorrenti, Agata Grazia D'Amico, Ignazio Barbagallo, Valeria Consoli, Salvo Grosso, Luca Vanella
Journal: Biomolecules
PubMed ID: 34205698
Doi: 10.3390/biom11060917
Products & Services: Nucleic Acid Purification & Analysis   
Long noncoding RNA SLC9A3‑AS1 increases E2F6 expression by sponging microRNA‑486‑5p and thus facilitates the oncogenesis of nasopharyngeal carcinoma
Authors: Jiansheng Li, Dongzhi Li, Xianhua Zhang, Cuijuan Li, Fengjuan Zhu
Journal: Oncol Rep
PubMed ID: 34165171
Doi: 10.3892/or.2021.8116
Products & Services: Gene Synthesis   
Production of Protocatechuic Acid from -Hydroxyphenyl (H) Units and Related Aromatic Compounds Using an Aspergillus niger Cell Factory
Authors: Ronnie J M Lubbers, Ronald P de Vries
Journal: MBio
PubMed ID: 34154420
Doi: 10.1128/mBio.00391-21
Products & Services: Gene Synthesis   
Novel Escherichia coli active site dnaE alleles with altered base and sugar selectivity
Authors: Alexandra Vaisman, Krystian Łazowski, Martin A M Reijns, Erin Walsh, John P McDonald, Kristiniana C Moreno, Dominic R Quiros, Marlen Schmidt, Harald Kranz, Wei Yang, Karolina Makiela-Dzbenska, Roger Woodgate
Journal: Mol Microbiol
PubMed ID: 34181784
Doi: 10.1111/mmi.14779
Products & Services: Gene Synthesis   
A methyl esterase 1 (PvMES1) promotes the salicylic acid pathway and enhances Fusarium wilt resistance in common beans
Authors: Renfeng Xue, Ming Feng, Jian Chen, Weide Ge, Matthew W Blair
Journal: Theor Appl Genet
PubMed ID: 34128089
Doi: 10.1007/s00122-021-03830-1
Products & Services: Peptide Synthesis   
Regulation of Krüppel-Like Factor 15 Expression by Herpes Simplex Virus Type 1 or Bovine Herpesvirus 1 Productive Infection
Authors: Fouad S El-Mayet, Kelly S Harrison, Clinton Jones
Journal: Viruses
PubMed ID: 34203849
Doi: 10.3390/v13061148
Products & Services: Custom Vector Construction   
Allosteric Activation of SARS-CoV-2 RNA-Dependent RNA Polymerase by Remdesivir Triphosphate and Other Phosphorylated Nucleotides
Authors: Bing Wang, Vladimir Svetlov, Yuri I Wolf, Eugene V Koonin, Evgeny Nudler, Irina Artsimovitch
Journal: MBio
PubMed ID: 34154407
Doi: 10.1128/mBio.01423-21
Products & Services: Custom Vector Construction   
Production of the infant formula ingredient 1,3-olein-2-palmitin in Arabidopsis thaliana seeds
Authors: Harrie van Erp, Fiona M Bryant, Jose Martin-Moreno, Louise V Michaelson, Peter J Eastmond
Journal: Metab Eng
PubMed ID: 34091040
Doi: 10.1016/j.ymben.2021.05.009
Products & Services: Codon Optimization   
Oral Administration of Producing Interferon Type II, Enhances the Immune Response Against Bacterial Pathogens in Rainbow Trout
Authors: Alvaro Santibañez, Diego Paine, Mick Parra, Carlos Muñoz, Natalia Valdes, Claudia Zapata, Rodrigo Vargas, Alex Gonzalez, Mario Tello
Journal: Front Immunol
PubMed ID: 34248997
Doi: 10.3389/fimmu.2021.696803
Products & Services: Codon Optimization   
Order and disorder-An integrative structure of the full-length human growth hormone receptor
Authors: Noah Kassem, Raul Araya-Secchi, Katrine Bugge, Abigail Barclay, Helena Steinocher, Adree Khondker, Yong Wang, Aneta J Lenard, Jochen Bürck, Cagla Sahin, Anne S Ulrich, Michael Landreh, Martin Cramer Pedersen, Maikel C Rheinstädter, Per Amstrup Pedersen, Kresten Lindorff-Larsen, Lise Arleth, Birthe B Kragelund
Journal: Sci Adv
PubMed ID: 34193419
Doi: 10.1126/sciadv.abh3805
Products & Services: Catalog Peptides   
Ultrapotent miniproteins targeting the SARS-CoV-2 receptor-binding domain protect against infection and disease
Authors: James Brett Case, Rita E Chen, Longxing Cao, Baoling Ying, Emma S Winkler, Max Johnson, Inna Goreshnik, Minh N Pham, Swathi Shrihari, Natasha M Kafai, Adam L Bailey, Xuping Xie, Pei-Yong Shi, Rashmi Ravichandran, Lauren Carter, Lance Stewart, David Baker, Michael S Diamond
Journal: Cell Host Microbe
PubMed ID: 34192518
Doi: 10.1016/j.chom.2021.06.008
Products & Services: Bacterial Expression   
Engineering Yarrowia lipolytica for de novo production of tetraacetyl phytosphingosine
Authors: Han C,Jang M,Kim MJ,Han MH,Lee KR,Hahn JS,Ahn J
Journal: Journal of applied microbiology
PubMed ID: 33190388
Doi: 10.1111/jam.14931
Products & Services: Gene Synthesis   
Membrane Env Liposomes Facilitate Immunization with Multivalent Full-Length HIV Spikes
Authors: Daniel P Leaman, Armando Stano, Yajing Chen, Lei Zhang, Michael B Zwick
Journal: J Virol
PubMed ID: 33883221
Doi: 10.1128/JVI.00005-21
Products & Services: Peptide Synthesis   
Targeting ribosomal G-quadruplexes with naphthalene-diimides as RNA polymerase I inhibitors for colorectal cancer treatment
Authors: Victoria Sanchez-Martin, David A Schneider, Matilde Ortiz-Gonzalez, Ana Soriano-Lerma, Angel Linde-Rodriguez, Virginia Perez-Carrasco, Jose Gutierrez-Fernandez, Marta Cuadros, Carlos González, Miguel Soriano, Jose A Garcia-Salcedo
Journal: Cell Chem Biol
PubMed ID: 34166611
Doi: 10.1016/j.chembiol.2021.05.021
Products & Services: Mammalian Expression   
Network Pharmacology Analysis of the Mechanisms of Compound Herba Sarcandrae (Fufang Zhongjiefeng) Aerosol in Chronic Pharyngitis Treatment
Authors: Yanping Zhang, Taohua Yuan, Yunsong Li, Ning Wu, Xiaotian Dai
Journal: Drug Des Devel Ther
PubMed ID: 34234411
Doi: 10.2147/DDDT.S304708
Products & Services: DNA Sequencing   
A single residue deletion in the barley HKT1;5 P189 variant restores plasma membrane localisation but not Na conductance
Authors: Stefanie Wege, Jiaen Qiu, Caitlin Byrt, Kelly Houston, Robbie Waugh, Matthew Gilliham, Maria Hrmova
Journal: Biochim Biophys Acta Biomembr
PubMed ID: 34139196
Doi: 10.1016/j.bbamem.2021.183669
Products & Services: Mutant Libraries   
Analogs of the Dopamine Metabolite 5,6-Dihydroxyindole Bind Directly to and Activate the Nuclear Receptor Nurr1
Authors: Svetlana A. Kholodar, Geoffrey Lang, Wilian A. Cortopassi, Yoshie Iizuka, Harman S. Brah, Matthew P. Jacobson, and Pamela M. England
Journal: ACS PUBLICATIONS
Doi: acschembio.1c00326
Products & Services: Gene Synthesis   
Phytochrome B interacts with SWC6 and ARP6 to regulate H2A.Z deposition and photomorphogensis in Arabidopsis
Authors: Xuxu Wei, Wanting Wang, Peng Xu, Wenxiu Wang, Tongtong Guo, Shuang Kou, Minqing Liu, Yake Niu, Hong‐Quan Yang and Zhilei Mao
Journal: Journal of integrative plant biology
PubMed ID: 33982818
Products & Services: Catalog Antibody   
Type 2 Nep1-Like Proteins from the Biocontrol Oomycete Pythium oligandrum Suppress Phytophthora capsici Infection in Solanaceous Plants
Authors: Kun Yang, Xiaohua Dong, Jialu Li, Yi Wang, Yang Cheng, Ying Zhai, Xiaobo Li, Lihui Wei, Maofeng Jing, and Daolong Dou
Journal: Journal of Fungi
PubMed ID: 34206578
Doi: 10.1016/j.molp.2021.05.007
Products & Services: Gene Synthesis   
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) moonlights as an adhesin in Mycoplasma hyorhinis adhesion to epithelial cells as well as a plasminogen receptor mediating extracellular matrix degradation
Authors: Jia Wang, Yao Li, Longji Pan, Jun Li, Yanfei Yu, Beibei Liu, Muhammad Zubair, Yanna Wei, Bala Pillay, Ademola Olufolahan Olaniran, Thamsanqa E. Chiliza, Guoqing Shao, Zhixin Feng and Qiyan Xiong
Journal: Veterinary research
PubMed ID: 34082810
Doi: 0.1186/s13567-021-00952-8
Products & Services: Gene Synthesis   
Fyn Knock-Down Prevents Levodopa-Induced Dyskinesia in a Mouse Model of Parkinson’s Disease
Authors: Melina P. Bordone, Ana Damianich, Alejandra Bernardi,Tomas Eidelman, Sara Sanz-Blasco, Oscar S. Gershanik,M. Elena Avale, and Juan E. Ferrario
Journal: eNeuro
PubMed ID: 34099487
Doi: 10.1523/ENEURO.0559-20.2021
Products & Services: Single-Stranded DNA Synthesis   
Development of an indirect ELISA for detecting swine acute diarrhoea syndrome coronavirus IgG antibodies based on a recombinant spike protein
Authors: Peng Peng, Yuepeng Gao, Qingfeng Zhou, Tianhua Jiang, Shumei Zheng, Meiyan Huang, Chunyi Xue, Yongchang Cao, Zhichao Xu
Journal: Transbound Emerg Dis
PubMed ID: 34148289
Doi: 10.1111/tbed.14196

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