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Generation and characterization of a nanobody against the avian influenza virus H7 subtype

Authors: Xiuqin Huang, Weiye Li, Xuewei Cao, Qi Zhang, Yizhen Lin, Siqi Xu, Xinying Dong, Peiqi Liu, Yutong Liu, Ge He, Kaijian Luo, Saixiang Feng

Journal: Int J Biol Macromol

PubMed ID: 38593899

Doi: 10.1016/j.ijbiomac.2024.131458

Products & Services: Catalog Antibody

Dietary Hemin Remodels Gut Microbiota and Mediates Tissue Inflammation and Injury in the Small Intestine

Authors: Qian Li, Weixin Ke, Shuai Jiang, Miao Zhang, Kai Shan, Chunbao Li

Journal: Mol Nutr Food Res

PubMed ID: 38676468

Doi: 10.1002/mnfr.202300889

Products & Services: Molecular Biology Reagents

Exploring the substrate spectrum of phylogenetically distinct bacterial polyesterases

Authors: Konstantinos Makryniotis, Efstratios Nikolaivits, George Taxeidis, Jasmina Nikodinovic-Runic, Evangelos Topakas

Journal: Biotechnol J

PubMed ID: 38593303

Doi: 10.1002/biot.202400053

Products & Services: Molecular Biology Reagents

Icariin attenuates vascular endothelial dysfunction by inhibiting inflammation through GPER/Sirt1/HMGB1 signaling pathway in type 1 diabetic rats

Authors: Wenhui Yao, Rongpin Tao, Kai Wang, Xuansheng Ding

Journal: Chin J Nat Med

PubMed ID: 38658093

Doi: 10.1016/S1875-5364(24)60618-7

Products & Services: Molecular Biology Reagents

Alternating Arenavirus Vector Immunization Generates Robust Polyfunctional Genotype Cross-Reactive Hepatitis B Virus-Specific CD8 T-Cell Responses and High Anti-Hepatitis B Surface Antigen Titers

Authors: Sarah Schmidt, Meron Mengistu, Stephane Daffis, Sarah Ahmadi-Erber, Daniela Deutschmann, Tetiana Grigoriev, Ruth Chu, Cleo Leung, Adrian Tomkinson, Mohammad Nizam Uddin, Safiehkhatoon Moshkani, Michael D Robek, Jason Perry, Henning Lauterbach, Klaus Orlinger, Simon P Fletcher, Scott Balsitis

Journal: J Infect Dis

PubMed ID: 37602681

Doi: 10.1093/infdis/jiad340

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Structure-Based Optimization of One Neutralizing Antibody against SARS-CoV-2 Variants Bearing the L452R Mutation

Authors: Yamin Chen, Jialu Zha, Shiqi Xu, Jiang Shao, Xiaoshan Liu, Dianfan Li, Xiaoming Zhang

Journal: Viruses

PubMed ID: 38675908

Doi: 10.3390/v16040566

Products & Services: Molecular Biology Reagents

Structural Insights into the Unexpected Agonism of Tetracyclic Antidepressants at Serotonin Receptors 5-HT1eR and 5-HT1FR

Authors: Gregory Zilberg, Alexandra K Parpounas, Audrey L Warren, Bianca Fiorillo, Davide Provasi, Marta Filizola, Daniel Wacker

Journal: SCIENCE ADVANCES

PubMed ID: 37986777

Doi: 10.1101/2023.10.05.561100

Products & Services: Proteins, Expression, Isolation and Analysis

CoCas9 is a compact nuclease from the human microbiome for efficient and precise genome editing

Authors: Eleonora Pedrazzoli, Michele Demozzi, Elisabetta Visentin, Matteo Ciciani, Ilaria Bonuzzi, Laura Pezzè, Lorenzo Lucchetta, Giulia Maule, Simone Amistadi, Federica Esposito, Mariangela Lupo, Annarita Miccio, Alberto Auricchio, Antonio Casini, Nicola Segata, Anna Cereseto

Journal: Nat Commun

PubMed ID: 38658578

Doi: 10.1038/s41467-024-47800-9

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Doxorubicin induces phosphorylation of lamin A/C and loss of nuclear membrane integrity: A novel mechanism of cardiotoxicity

Authors: Vikas Tiwari, Paras Gupta, Navya Malladi, Sanjay Salgar, Sanjay K Banerjee

Journal: Free Radic Biol Med

PubMed ID: 38582228

Doi: 10.1016/j.freeradbiomed.2024.04.212

Products & Services: ORF cDNA Clones/MolecularCloud

LINC02605 involved in paediatric Mycoplasma pneumoniae pneumonia complicated with diarrhoea via miR-539-5p/CXCL1 axis

Authors: Yang Zhang, Zeming Wu

Journal: Eur J Clin Invest

PubMed ID: 38662581

Doi: 10.1111/eci.14234

Products & Services: PCR Cloning and Subcloning

Co-delivery of Cas9 mRNA and guide RNAs for editing of LGMN gene represses breast cancer cell metastasis

Authors: Yue Wang, Yatu Peng, Guanghui Zi, Jin Chen, Baowei Peng

Journal: Sci Rep

PubMed ID: 38582932

Doi: 10.1038/s41598-024-58765-6

Products & Services: Proteins, Expression, Isolation and Analysis

Functionalizing Yeast Lipid Droplets as Versatile Biomaterials

Authors: Ankita Suri, Kevin K Y Hu, Tayyaba Younas, Geoff Dumsday, Victoria S Haritos

Journal: Small

PubMed ID: 38566530

Doi: 10.1002/smll.202308463

Products & Services: Proteins, Expression, Isolation and Analysis

Inhibition of USP7 enhances CD8 T cell activity in liver cancer by suppressing PRDM1-mediated FGL1 upregulation

Authors: Lin-Lin Sun, Li-Na Zhao, Jiao Sun, Hong-Feng Yuan, Yu-Fei Wang, Chun-Yu Hou, Pan Lv, Hui-Hui Zhang, Guang Yang, Ning-Ning Zhang, Xiao-Dong Zhang, Wei Lu

Journal: Acta Pharmacol Sin

PubMed ID: 38589688

Doi: 10.1038/s41401-024-01263-2

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Development of a multiplex droplet digital PCR method for detection and monitoring of Mycobacterium tuberculosis and drug-resistant tuberculosis

Authors: Yu Jeong Choi, Yoonjung Kim, Hye Jung Park, Dokyun Kim, Hyukmin Lee, Young Ah Kim, Kyung-A Lee

Journal: Ann Clin Microbiol Antimicrob

PubMed ID: 38581051

Doi: 10.1186/s12941-024-00687-2

Products & Services: Molecular Biology Reagents

Unveiling orphan receptor-like kinases in plants: novel client discovery using high-confidence library predictions in the Kinase-Client (KiC) assay

Authors: Gabriel Lemes Jorge, Daewon Kim, Chunhui Xu, Sung-Hwan Cho, Lingtao Su, Dong Xu, Laura E Bartley, Gary Stacey, Jay J Thelen

Journal: Front Plant Sci

PubMed ID: 38633461

Doi: 10.3389/fpls.2024.1372361

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Dysfunction of the adhesion G protein-coupled receptor latrophilin 1 (ADGRL1/LPHN1) increases the risk of obesity

Authors: André Nguyen Dietzsch, Hadi Al-Hasani, Joachim Altschmied, Katharina Bottermann, Jana Brendler, Judith Haendeler, Susanne Horn, Isabell Kaczmarek, Antje Körner, Kerstin Krause, Kathrin Landgraf, Diana Le Duc, Laura Lehmann, Stefan Lehr, Stephanie Pick, Albert Ricken, Rene Schnorr, Angela Schulz, Martina Strnadová, Akhil Velluva, Heba Zabri, Torsten Schöneberg, Doreen Thor, Simone Prömel

Journal: Signal Transduct Target Ther

PubMed ID: 38664368

Doi: 10.1038/s41392-024-01810-7

Products & Services: Molecular Biology Reagents

Development and characterization of a bacterial enzyme cascade reaction system for efficient and stable PET degradation

Authors: Chengyong Wang, Rui Long, Xiran Lin, Wei Liu, Liying Zhu, Ling Jiang

Journal: J Hazard Mater

PubMed ID: 38703683

Doi: 10.1016/j.jhazmat.2024.134480

Products & Services: Molecular Biology Reagents

Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial

Authors: Mark Yarchoan, Edward J Gane, Thomas U Marron, Renzo Perales-Linares, Jian Yan, Neil Cooch, Daniel H Shu, Elana J Fertig, Luciane T Kagohara, Gabor Bartha, Josette Northcott, John Lyle, Sarah Rochestie, Joann Peters, Jason T Connor, Elizabeth M Jaffee, Ildiko Csiki, David B Weiner, Alfredo Perales-Puchalt, Niranjan Y Sardesai

Journal: Nat Med

PubMed ID: 38584166

Doi: 10.1038/s41591-024-02894-y

Products & Services: Molecular Biology Reagents

Chimeric Porcine Parvovirus VP2 Virus-like Particles with Epitopes of South African Serotype 2 Foot-and-Mouth Disease Virus Elicits Specific Humoral and Cellular Responses in Mice

Authors: Qian Li, Xusheng Ma, Yaner Shen, Junfei Dai, Xiaofeng Nian, Xiaofen Shang, Jiao Chen, Ashenafi Kiros Wubshet, Jie Zhang, Haixue Zheng

Journal: Viruses

PubMed ID: 38675963

Doi: 10.3390/v16040621

Products & Services: Gene Synthesis

Correction: Nintedanib downregulates the profibrotic M2 phenotype in cultured monocyte-derived macrophages obtained from systemic sclerosis patients affected by interstitial lung disease

Authors: Stefano Soldano, Vanessa Smith, Paola Montagna, Emanuele Gotelli, Rosanna Campitiello, Carmen Pizzorni, Sabrina Paolino, Alberto Sulli, Andrea Cere, Maurizio Cutolo

Journal: Arthritis Res Ther

PubMed ID: 38600545

Doi: 10.1186/s13075-024-03319-4

Products & Services: Proteins, Expression, Isolation and Analysis

Functional screening of the Arabidopsis 2C protein phosphatases family identifies PP2C15 as a negative regulator of plant immunity by targeting BRI1-associated receptor kinase 1

Authors: Zhihong Diao, Rongqian Yang, Yizhu Wang, Junmei Cui, Junhao Li, Qiqi Wu, Yaxin Zhang, Xiaosong Yu, Benqiang Gong, Yan Huang, Guozhi Yu, Huipeng Yao, Jinya Guo, Huaiyu Zhang, Jinbo Shen, Andrea A Gust, Yi Cai

Journal: Mol Plant Pathol

PubMed ID: 38561315

Doi: 10.1111/mpp.13447

Products & Services: Proteins, Expression, Isolation and Analysis

Assembly of SARS-CoV-2 nucleocapsid protein with nucleic acid

Authors: Huaying Zhao, Abdullah M Syed, Mir M Khalid, Ai Nguyen, Alison Ciling, Di Wu, Wai-Ming Yau, Sanjana Srinivasan, Dominic Esposito, Jennifer A Doudna, Grzegorz Piszczek, Melanie Ott, Peter Schuck

Journal: Nucleic Acids Res

PubMed ID: 38587193

Doi: 10.1093/nar/gkae256

Products & Services: Plasmid DNA Preparation

Photo-Responsive Decellularized Small Intestine Submucosa Hydrogels

Authors: Van Thuy Duong, Han Dang Nguyen, Ngoc Ha Luong, Chun-Yi Chang, Chien-Chi Lin

Journal: Advanced Functional Materials

Doi: 10.1002/adfm.202401952

Products & Services: Peptide Synthesis

Assessing Weak Anion Binding to Small Peptides

Authors: Corinne L D Gibb, Thien H Tran, Bruce C Gibb

Journal: Journal of the American Chemical Society

PubMed ID: 38592238

Doi: 10.1021/acs.jpcb.4c00657

Products & Services: Peptide Synthesis

Detecting m6A at single-molecular resolution via direct RNA sequencing and realistic training data

Authors: Adrian Chan, Isabel S Naarmann-de Vries, Carolin P M Scheitl, Claudia Höbartner,Christoph Dieterich

Journal: Nature Communications

PubMed ID: 38637518

Doi: 10.1038/s41467-024-47661-2

Products & Services: Custom DNA/RNA Oligos

Immune microniches shape intestinal T function

Authors: Yisu Gu, Raquel Bartolomé-Casado, Chuan Xu, Alice Bertocchi, Alina Janney, Cornelia Heuberger, Claire F Pearson, Sarah A Teichmann, Emily E Thornton, Fiona Powrie

Journal: Nature

PubMed ID: 38570678

Doi: 10.1038/s41586-024-07251-0

Products & Services: Catalog Peptides

Delivering large genes using adeno-associated virus and the CRE-lox DNA recombination system

Authors: Poppy Datta, Kun Do Rhee, Rylee J Staudt, Jacob M Thompson, Ying Hsu, Salma Hassan, Arlene V Drack, Seongjin Seo

Journal: Human Molecular Genetics

PubMed ID: 38645107

Doi: 10.1101/2024.04.10.588864

Products & Services: PCR and Cloning ORF cDNA Clones/MolecularCloud

A distinct tumor microenvironment makes anaplastic thyroid cancer more lethal but immunotherapy sensitive than papillary thyroid cancer

Authors: Pei-Zhen Han, Wei-Dong Ye, Peng-Cheng Yu, Li-Cheng Tan, Xiao Shi, Xu-Feng Chen, Cong He, Jia-Qian Hu, Wen-Jun Wei, Zhong-Wu Lu, Ning Qu, Yu Wang, Qing-Hai Ji, Dong-Mei Ji, Yu-Long Wang

Journal: JCI Insight

PubMed ID: 38478516

Doi: 10.1172/jci.insight.173712

Products & Services: Molecular Biology Reagents

The Novel MFG-E8-derived Oligopeptide, MOP3, Improves Outcomes in a Preclinical Murine Model of Neonatal Sepsis

Authors: Colleen P Nofi, Jose M Prince, Monowar Aziz, Ping Wang

Journal: J Pediatr Surg

PubMed ID: 38582704

Doi: 10.1016/j.jpedsurg.2024.03.025

Products & Services: Peptide Synthesis

Separation and purification of short-, medium-, and long-stranded RNAs by RP-HPLC using different mobile phases and C columns with various pore sizes

Authors: Makoto Ozaki, Tomomi Kuwayama, Motoshi Shimotsuma, Tsunehisa Hirose

Journal: Anal Methods

PubMed ID: 38445900

Doi: 10.1039/d4ay00114a

Products & Services: Gene Synthesis

Exploring the enigmatic association between PNLIP variants and risk of chronic pancreatitis in a large Chinese cohort

Authors: Brett M Cassidy, Fei Jiang, Jianguo Lin, Jian-Min Chen, Grace E Curry, Guo-Xiu Ma, Steven J Wilhelm, Shun-Jiang Deng, Guoying Zhu, Zhuan Liao, Mark E Lowe, Xunjun K Xiao, Wen-Bin Zou

Journal: Pancreatology

PubMed ID: 38485544

Doi: 10.1016/j.pan.2024.03.002

Products & Services: Mutagenesis Services

WDR4 promotes HCC pathogenesis through N-methylguanosine by regulating and interacting with METTL1

Authors: Rui Dong, Chuanxu Wang, Bo Tang, Yayu Cheng, Xuehui Peng, Xiaomin Yang, Bing Ni, Jing Li

Journal: Cell Signal

PubMed ID: 38493882

Doi: 10.1016/j.cellsig.2024.111145

Products & Services: Proteins, Expression, Isolation and Analysis

Cross-reactive CD8 T cell responses to tumor-associated antigens (TAAs) and homologous microbiota-derived antigens (MoAs)

Authors: Beatrice Cavalluzzo, Marie Christine Viuff, Siri Amanda Tvingsholm, Concetta Ragone, Carmen Manolio, Angela Mauriello, Franco M Buonaguro, Maria Lina Tornesello, Francesco Izzo, Alessandro Morabito, Sine Reker Hadrup, Maria Tagliamonte, Luigi Buonaguro

Journal: J Exp Clin Cancer Res

PubMed ID: 38509571

Doi: 10.1186/s13046-024-03004-z

Products & Services: Catalog Peptides

Inhibitory effects of senkyuchachosan on SARS-CoV-2 papain-like protease activity in vitro

Authors: Yuka Kiba, Takashi Tanikawa, Tsuyoshi Hayashi, Takami Yokogawa, Aiko Sano, Ryuichiro Suzuki, Masashi Kitamura

Journal: J Nat Med

PubMed ID: 38512650

Doi: 10.1007/s11418-024-01788-0

Products & Services: Molecular Biology Reagents

Diagnosis of fasciolosis antibodies in Brazilian cattle through ELISA employing both native and recombinant antigens

Authors: Guilherme Drescher, Hellen Geremias Dos Santos, Mariane Marques da Guarda Pinto, Luis Gustavo Morello, Fabiano Borges Figueiredo

Journal: Microbiol Spectr

PubMed ID: 38534120

Doi: 10.1128/spectrum.00095-24

Products & Services: Molecular Biology Reagents

Structural insights into human EMC and its interaction with VDAC

Authors: Mingyue Li, Chunli Zhang, Yuntao Xu, Shaobai Li, Chenhui Huang, Jian Wu, Ming Lei

Journal: Aging (Albany NY)

PubMed ID: 38517390

Doi: 10.18632/aging.205660

Products & Services: Proteins, Expression, Isolation and Analysis

Expression, purification, and biological activity evaluation of cathepsin L in mammalian cells

Authors: Wenwen Zhou, Baoqing You, Yifan Zheng, Shuyi Si, Yan Li, Jing Zhang

Journal: Biosci Biotechnol Biochem

PubMed ID: 38271604

Doi: 10.1093/bbb/zbae005

Products & Services: Molecular Biology Reagents

A T cell-based SARS-CoV-2 spike protein vaccine provides protection without antibodies

Authors: Juan Shi, Jian Zheng, Xiujuan Zhang, Wanbo Tai, Ryan Compas, Jack Deno, Natalie Jachym, Abhishek K Verma, Gang Wang, Xiaoqing Guan, Abby E Odle, Yushun Wan, Fang Li, Stanley Perlman, Liang Qiao, Lanying Du

Journal: JCI Insight

PubMed ID: 38456504

Doi: 10.1172/jci.insight.155789

Products & Services: Molecular Biology Reagents

Development and Evaluation of an Immunoinformatics-Based Multi-Peptide Vaccine against Infection

Authors: Sean Jeffreys, Megan P Tompkins, Jadelynn Aki, Sara B Papp, James P Chambers, M Neal Guentzel, Chiung-Yu Hung, Jieh-Juen Yu, Bernard P Arulanandam

Journal: Vaccines (Basel)

PubMed ID: 38675740

Doi: 10.3390/vaccines12040358

Products & Services: Molecular Biology Reagents

Preparation and immunogenicity evaluation of C-HapS-P6 fusion protein vaccine against nontypeable Haemophilus influenzae in mice

Authors: Nan Hu, Weifeng Li, Zihong Zhao, Yueli Chang, Cai Wang, Yutuo Zhang

Journal: Int J Med Microbiol

PubMed ID: 38461565

Doi: 10.1016/j.ijmm.2024.151616

Products & Services: Proteins, Expression, Isolation and Analysis

Characterization of Probiotic Properties and Whole-Genome Analysis of N5 and N7 Isolated from Swine

Authors: Kun Wang, Yu Wang, Lifang Gu, Jinyan Yu, Qianwen Liu, Ruiqi Zhang, Guixin Liang, Huan Chen, Fang Gu, Haoyu Liu, Xin'an Jiao, Yunzeng Zhang

Journal: Microorganisms

PubMed ID: 38674616

Doi: 10.3390/microorganisms12040672

Products & Services: DNA Sequencing

Dual mechanisms contribute to enhanced voltage dependence of an electric fish potassium channel

Authors: Jelena Todorovic, Immani Swapna, Antonio Suma, Vincenzo Carnevale, Harold Zakon

Journal: Biophys J

PubMed ID: 38429925

Doi: 10.1016/j.bpj.2024.02.028

Products & Services: Catalog Peptides

Antigenicity, epitope mapping, and intracellular distribution of the NSP7α protein of porcine reproductive and respiratory syndrome virus

Authors: Tao Wang, Da-Song Xia, Xiao-Xiao Tian, Yong-Bo Yang, Tong-Qing An

Journal: Int J Biol Macromol

PubMed ID: 38493809

Doi: 10.1016/j.ijbiomac.2024.130944

Products & Services: Proteins, Expression, Isolation and Analysis

Safety and Immunogenicity of a Messenger RNA-Based Cytomegalovirus Vaccine in Healthy Adults: Results From a Phase 1, Randomized, Clinical Trial

Authors: Carlos Fierro, Daniel Brune, Marian Shaw, Howard Schwartz, Conor Knightly, Jiang Lin, Andrea Carfi, Andrew Natenshon, Shiva Kalidindi, Caroline Reuter, Jacqueline Miller, Lori Panther

Journal: J Infect Dis

PubMed ID: 38478705

Doi: 10.1093/infdis/jiae114

Products & Services: Peptide Tools

Rapid and Mechanically Robust Immobilization of Proteins on Silica Studied at the Single-Molecule Level by Force Spectroscopy and Verified at the Macroscopic Level

Authors: Xiaoxu Zhang, Yayan Xie, Duo Huang, Xiaozhong Zhang, Xiaoyu Tang, Long Chen, Shi-Zhong Luo, Jizhong Lou, Chengzhi He

Journal: ACS Appl Mater Interfaces

PubMed ID: 38520330

Doi: 10.1021/acsami.3c18699

Products & Services: Catalog Peptides

The protein methyltransferase TrSAM inhibits cellulase gene expression by interacting with the negative regulator ACE1 in Trichoderma reesei

Authors: Zhihua Zhu, Gen Zou, Shunxing Chai, Meili Xiao, Yinmei Wang, Pingping Wang, Zhihua Zhou

Journal: Commun Biol

PubMed ID: 38548869

Doi: 10.1038/s42003-024-06072-1

Products & Services: Proteins, Expression, Isolation and Analysis

The human microbiota is a beneficial reservoir for SARS-CoV-2 mutations

Authors: Birong Cao, Xiaoxi Wang, Wanchao Yin, Zhaobing Gao, Bingqing Xia

Journal: MBio

PubMed ID: 38530031

Doi: 10.1128/mbio.03187-23

Products & Services: Proteins, Expression, Isolation and Analysis

Phenotypic characterization of sorghum seedlings and expression patterns of SNAC1 and DREB1A genes under water‑stress: an insight towards developing resilient cultivars

Authors: David Adedayo Animasaun · Khadijat Adetoun Adedoyin · Afeez Taiwo Bakare · Kabir Adeniran Mustapha · Mary Anuoluwapo Akinbobola · Kafayat Folasade Awujoola · Jonathan Toyin Ogunjobi

Journal: springerlink

Doi: 10.1007/s10722-024-01956-x

Products & Services: Gene Synthesis

Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria

Authors: Stian Foss , Siri A Sakya, Leire Aguinagalde, Marta Lustig, Jutamas Shaughnessy, Ana Rita Cruz , Lisette Scheepmaker, Line Mathiesen, Fulgencio Ruso-Julve, Aina Karen Anthi, Torleif Tollefsrud Gjølberg

Journal: Nature Communications

PubMed ID: 38453922

Doi: 10.1038/s41467-024-46321-9

Products & Services: Gene Synthesis

Decoding chromatin states by proteomic profiling of nucleosome readers

Authors: Saulius Lukauskas, Andrey Tvardovskiy, Nhuong V Nguyen , Mara Stadler, Peter Faull, Tina Ravnsborg, Bihter Özdemir Aygenli, Scarlett Dornauer, Helen Flynn, Rik G H Lindeboom, Teresa K Barth, Kevin Brockers, Stefanie M Hauck, Michiel Vermeulen, Ambrosius P Snijders, Christian L Müller, Peter A DiMaggio, Ole N Jensen, Robert Schneider, Till Bartke

Journal: Nature

PubMed ID: 38448585

Doi: 10.1038/s41586-024-07141-5

Products & Services: Codon Optimization

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