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YeeD is an essential partner for YeeE-mediated thiosulfate uptake in bacteria and regulates thiosulfate ion decomposition

Authors: Mai Ikei, Ryoji Miyazaki, Keigo Monden, Yusuke Naito, Azusa Takeuchi, Yutaro S Takahashi, Yoshiki Tanaka, Keina Murata, Takaharu Mori, Muneyoshi Ichikawa, Tomoya Tsukazaki

Journal: PLoS Biol

PubMed ID: 38656967

Doi: 10.1371/journal.pbio.3002601

Products & Services: Gene Synthesis

Neutrophil proteases are protective against SARS-CoV-2 by degrading the spike protein and dampening virus-mediated inflammation

Authors: Nathan Gf Leborgne, Christelle Devisme, Nedim Kozarac, Inês Berenguer Veiga, Nadine Ebert, Aurélie Godel, Llorenç Grau-Roma, Melanie Scherer, Philippe Plattet, Volker Thiel, Gert Zimmer, Adriano Taddeo, Charaf Benarafa

Journal: JCI Insight

PubMed ID: 38470488

Doi: 10.1172/jci.insight.174133

Products & Services: Proteins, Expression, Isolation and Analysis

Photodynamic therapy upregulates expression of HIF-1α and PD-L1 in related pathways and its clinical relevance in non-small-cell lung cancer

Authors: Wen Sun, Yuan Cheng, Xiaoyu Ma, Zhou Jin, Qi Zhang, Guangfa Wang

Journal: Eur J Med Res

PubMed ID: 38609977

Doi: 10.1186/s40001-024-01780-0

Products & Services: Molecular Biology Reagents

Bioinformatics, expression analysis, and functional verification of allene oxide synthase gene and in qingke

Authors: Likun An, Ziao Wang, Yongmei Cui, Youhua Yao, Yixiong Bai, Yuehai Liu, Xin Li, Xiaohua Yao, Kunlun Wu

Journal: Open Life Sci

PubMed ID: 38681731

Doi: 10.1515/biol-2022-0855

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of distinct immune signatures in inclusion body myositis by peripheral blood immunophenotyping using machine learning models

Authors: Emily McLeish, Anuradha Sooda, Nataliya Slater, Kelly Beer, Ian Cooper, Frank L Mastaglia, Merrilee Needham, Jerome D Coudert

Journal: Clin Transl Immunology

PubMed ID: 38585335

Doi: 10.1002/cti2.1504

Products & Services: Proteins, Expression, Isolation and Analysis

Lipopolysaccharide modification enhances the inhibitory effect of clodronate liposomes on hepatic fibrosis by depletion of macrophages and hepatic stellate cells

Authors: Luyao Zhang, Min Tao, Hengyan Zhang, Shichao Zhang, Xiaojuan Hou, Chen Zong, Gangqi Sun, Shiyao Feng, Haixin Yan, Ying Lu, Xue Yang, Lixin Wei, Li Zhang

Journal: Chem Biol Interact

PubMed ID: 38663797

Doi: 10.1016/j.cbi.2024.111015

Products & Services: Molecular Biology Tools

Significant but partial lipoprotein lipase functional loss caused by a novel occurrence of rare LPL biallelic variants

Authors: Yuepeng Hu, Jian-Min Chen, Han Zuo, Na Pu, Guofu Zhang, Yichen Duan, Gang Li, Zhihui Tong, Weiqin Li, Baiqiang Li, Qi Yang

Journal: Lipids Health Dis

PubMed ID: 38561841

Doi: 10.1186/s12944-024-02086-0

Products & Services: Molecular Biology Reagents

Diverse Class 2 CRISPR Effectors as Active Nucleases with Expanded Targeting Capabilities

Authors: Meng Wang, Lila Rieber, Jessica van Baaren, Meaghan Morgan, Stephanie Merrett, Ian McDowell, Tyson Bowen

Journal: CRISPR J

PubMed ID: 38635326

Doi: 10.1089/crispr.2023.0058

Products & Services: Codon Optimization

Identification of Enhanced Vaccine Mimotopes for the p15E Murine Cancer Antigen

Authors: Shiqi Zhou, Yiting Song, Yuan Luo, Breandan Quinn, Yang Jiao, Mark D Long, Scott I Abrams, Jonathan F Lovell

Journal: Cancer Res Commun

PubMed ID: 38506662

Doi: 10.1158/2767-9764.CRC-23-0384

Products & Services: Catalog Peptides

Metal-Binding Protein TaGlo1 Improves Fungal Resistance to Arsenite (As) and Methylarsenite (MAs) in Paddy Soil

Authors: Lijuan Li, Jian Tian, Ke Huang, Ximei Xue, Jian Chen, Feifei Guan, Tuo Zhang, Yifei Sun, Chao He, Xibai Zeng, Shiming Su

Journal: Environ Sci Technol

PubMed ID: 38557082

Doi: 10.1021/acs.est.3c11043

Products & Services: Mutant Libraries

Engineering, structure, and immunogenicity of a Crimean-Congo hemorrhagic fever virus pre-fusion heterotrimeric glycoprotein complex

Authors: Elizabeth McFadden, Stephanie R Monticelli, Albert Wang, Ajit R Ramamohan, Thomas G Batchelor, Ana I Kuehne, Russell R Bakken, Alexandra L Tse, Kartik Chandran, Andrew S Herbert, Jason S McLellan

Journal: biorxiv

PubMed ID: 38659837

Doi: 10.1101/2024.04.20.590419

Products & Services: Codon Optimization

Interaction of ubiquitin-like protein SILENCING DEFECTIVE 2 with LIKE HETEROCHROMATIN PROTEIN 1 is required for regulation of anthocyanin biosynthesis in Arabidopsis thaliana in response to sucrose

Authors: Zhiyi Zhang, Chengcheng Liang, Yulong Ren, Zhaojun Lv, Jirong Huang

Journal: New Phytol

PubMed ID: 38558017

Doi: 10.1111/nph.19725

Products & Services: Molecular Biology Reagents

RBM22 regulates RNA polymerase II 5' pausing, elongation rate, and termination by coordinating 7SK-P-TEFb complex and SPT5

Authors: Xian Du, Wenying Qin, Chunyu Yang, Lin Dai, Mingkui San, Yingdan Xia, Siyu Zhou, Mengyang Wang, Shuang Wu, Shaorui Zhang, Huiting Zhou, Fangshu Li, Fang He, Jingfeng Tang, Jia-Yu Chen, Yu Zhou, Rui Xiao

Journal: Genome Biology

PubMed ID: 38641822

Doi: 10.1186/s13059-024-03242-6

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Structural basis for dimerization of a paramyxovirus polymerase complex

Authors: Jin Xie, Mohamed Ouizougun-Oubari, Li Wang, Guanglei Zhai, Daitze Wu, Zhaohu Lin, Manfu Wang, Barbara Ludeke, Xiaodong Yan, Tobias Nilsson, Lu Gao, Xinyi Huang, Rachel Fearns, Shuai Chen

Journal: Nature Communications

PubMed ID: 38605025

Doi: 10.1038/s41467-024-47470-7

Products & Services: Proteins, Expression, Isolation and Analysis

Statins improve cardiac endothelial function to prevent heart failure with preserved ejection fraction through upregulating circRNA-RBCK1

Authors: Bin Li, Wen-Wu Bai, Tao Guo, Zhen-Yu Tang, Xue-Jiao Jing, Ti-Chao Shan, Sen Yin, Ying Li, Fu Wang, Mo-Li Zhu, Jun-Xiu Lu, Yong-Ping Bai, Bo Dong, Peng Li, Shuang-Xi Wang

Journal: Nat Commun

PubMed ID: 38580662

Doi: 10.1038/s41467-024-47327-z

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Fuzzy recognition by the prokaryotic transcription factor HigA2 from Vibrio cholerae

Authors: San Hadži, Zala Živič , Matic Kovačič , Uroš Zavrtanik , Sarah Haeserts, Daniel Charlier, Janez Plavec, Alexander N Volkov, Jurij Lah, Remy Loris

Journal: Nature Communications

PubMed ID: 38600130

Doi: 10.1038/s41467-024-47296-3

Products & Services: PCR Cloning and Subcloning

Transcription bodies regulate gene expression by sequestering CDK9

Authors: Martino Ugolini, Maciej A Kerlin, Ksenia Kuznetsova, Haruka Oda, Hiroshi Kimura, Nadine L Vastenhouw

Journal: Nature Cell Biology

PubMed ID: 38589534

Doi: 10.1038/s41556-024-01389-9

Products & Services: Custom DNA/RNA Oligos

Oncolytic adenovirus encoding apolipoprotein A1 suppresses metastasis of triple-negative breast cancer in mice

Authors: Jie Dong, Lingkai Kong, Shiqun Wang, Mao Xia, Yenan Zhang, Jingyi Wu, Fuming Yang, Shuguang Zuo, Jiwu Wei

Journal: Experimental & Clinical Cancer Research

PubMed ID: 38566092

Doi: 10.1186/s13046-024-03011-0

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The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis

Authors: Victor E Cruz, Christine S Weirich, Nagesh Peddada, Jan P Erzberger

Journal: Nat Commun

PubMed ID: 38632236

Doi: 10.1038/s41467-024-47616-7

Products & Services: Gene Synthesis

Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers

Authors: Stephane Ferretti, Jacques Hamon, Ruben de Kanter, Clemens Scheufler，Henrik Möbitz, Marta Cortés-Cros

Journal: Nature

PubMed ID: 38658754

Doi: 10.1038/s41586-024-07350-y

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

SARS-CoV-2 nsp15 preferentially degrades AU-rich dsRNA via its dsRNA nickase activity

Authors: Xionglue Wang, Bin Zhu

Journal: Nucleic Acids Res

PubMed ID: 38634805

Doi: 10.1093/nar/gkae290

Products & Services: Custom DNA/RNA Oligos

Bioactive fiber-reinforced hydrogel to tailor cell microenvironment for structural and functional regeneration of myotendinous junction

Authors: Yuzhi Sun 1, Renwang Sheng 2, Zhicheng Cao 1, Chuanquan Liu 2, Jiaxiang Li 1, Po Zhang 1, Yan Du 2, Qingyun Mo 2, Qingqiang Yao 1 3, Jialin Chen 2 3 4, Wei Zhang 2 3 4

Journal: Sci Adv

PubMed ID: 38657071

Doi: 10.1126/sciadv.adm7164

Products & Services: Recombinant Proteins

The Transpeptidase Sortase A Binds Nucleic Acids and Mediates Mammalian Cell Labeling

Authors: Yingzheng Liu, Zhike Lu, Panfeng Wu, Zhaohui Liang, Zhenxing Yu, Ke Ni, Lijia Ma

Journal: Adv Sci (Weinh)

PubMed ID: 38581131

Doi: 10.1002/advs.202305605

Products & Services: Proteins, Expression, Isolation and Analysis

Biomolecular investigations into BBI reveal an enzymatic mechanism for PUFA isomerisation in bifidobacterium CFA bioconversion strains

Authors: Yongchao Mei, Lulu Chang, Yibin Ji, Bo Yang, Jianxin Zhao, Haiqin Chen, Wei Chen

Journal: Int J Biol Macromol

PubMed ID: 38692553

Doi: 10.1016/j.ijbiomac.2024.131836

Products & Services: Molecular Biology Reagents

Precision miRNA profiling: Electrochemiluminescence powered by CRISPR-Cas13a and hybridization chain reaction

Authors: Jihua Wei, Jiayi Zhang, Wei Wang, Haidong Zhou, Huade Ma, Yuanxun Gong, Qianli Tang, Kai Zhang, Xianjiu Liao

Journal: Anal Chim Acta

PubMed ID: 38719418

Doi: 10.1016/j.aca.2024.342641

Products & Services: DNA Sequencing

Safe plant Hsp90 adjuvants elicit an effective immune response against SARS-CoV2-derived RBD antigen

Authors: Victor A Ramos-Duarte, Alejandro Orlowski, Carolina Jaquenod de Giusti, Mariana G Corigliano, Ariel Legarralde, Luisa F Mendoza-Morales, Agustín Atela, Manuel A Sánchez, Valeria A Sander, Sergio O Angel, Marina Clemente

Journal: Vaccine

PubMed ID: 38631949

Doi: 10.1016/j.vaccine.2024.04.036

Products & Services: Custom Vector Construction

Chitosan-LeoA-DNA Nanoparticles Promoted the Efficacy of Novel LeoA-DNA Vaccination on Mice Against Helicobacter pylori

Authors: Zahra Ahmadzadeh Chaleshtori, Ali Asghar Rastegari, Hashem Nayeri, Abbas Doosti

Journal: Curr Microbiol

PubMed ID: 38558085

Doi: 10.1007/s00284-024-03642-8

Products & Services: Molecular Biology Tools

Identification and affinity enhancement of T-cell receptor targeting a KRAS cancer neoantigen

Authors: Mengyu Zhang, Wei Xu, Lingjie Luo, Fenghui Guan, Xiangyao Wang, Pei Zhu, Jianhua Zhang, Xuyu Zhou, Feng Wang, Sheng Ye

Journal: Commun Biol

PubMed ID: 38684865

Doi: 10.1038/s42003-024-06209-2

Products & Services: Molecular Biology Reagents

Exploring immune evasion of SARS-CoV-2 variants using a pseudotyped system

Authors: Haixiao Duan, Ershuai Zhang, Ge Ren, Yining Cheng, Binfeng Yang, Lirong Liu, Normand Jolicoeur, Han Hu, Yan Xu, Binlei Liu

Journal: Heliyon

PubMed ID: 38699727

Doi: 10.1016/j.heliyon.2024.e29939

Products & Services: Gene Synthesis

Application of Cas12j for Editing

Authors: Lee Ling Tan, Elena Heng, Chung Yan Leong, Veronica Ng, Lay Kien Yang, Deborah Chwee San Seow, Lokanand Koduru, Yoganathan Kanagasundaram, Siew Bee Ng, Guangrong Peh, Yee Hwee Lim, Fong Tian Wong

Journal: Biomolecules

PubMed ID: 38672502

Doi: 10.3390/biom14040486

Products & Services: Gene Synthesis

Remodeling the Homologous Recombination Mechanism of for High-Level Biosynthesis of Squalene

Authors: Man Xu, Nan Yang, Jiang Pan, Qiang Hua, Chun-Xiu Li, Jian-He Xu

Journal: J Agric Food Chem

PubMed ID: 38635942

Doi: 10.1021/acs.jafc.4c01779

Products & Services: Gene Synthesis

CRISPR Screen Identifies the RNA-Binding Protein Eef1a1 as a Key Regulator of Myogenesis

Authors: Weiwei Liu, Wei Wang, Zishuai Wang, Xinhao Fan, Wangchang Li, Yuxin Huang, Xiaogan Yang, Zhonglin Tang

Journal: Int J Mol Sci

PubMed ID: 38732031

Doi: 10.3390/ijms25094816

Products & Services: Custom DNA/RNA Oligos

Roles of a newly lethal cuticular structural protein, AaCPR100A, and its upstream interaction protein, G12-like, in Aedes aegypti

Authors: Jing Chen, Yuchen Wu, Jiukai Chen, Haoran Lu, Gong Cheng, Zhijian Jake Tu, Chenghong Liao, Qian Han

Journal: Int J Biol Macromol

PubMed ID: 38670198

Doi: 10.1016/j.ijbiomac.2024.131704

Products & Services: Proteins, Expression, Isolation and Analysis

CRISPR/CasΦ2-mediated gene editing in wheat and rye

Authors: Sanzeng Zhao , Xueying Han , Yachen Zhu , Yuwei Han , Huiyun Liu , Zhen Chen , Huifang Li , Dan Wang , Chaofan Tian , Yuting Yuan , Yajie Guo , Xiaomin Si , Daowen Wang, Xiang Ji

Journal: J Integr Plant Biol

PubMed ID: 38351739

Doi: 10.1111/jipb.13624

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The miR184-3p targets neuron-specific ecdysone inducible protein 78 to promote rice black streaked dwarf virus propagation in its planthopper vector

Authors: Haitao Wang, Yan Dong, Man Wang, Shuo Li, Yijun Zhou, Yinghua Ji

Journal: Pest Manag Sci

PubMed ID: 38676556

Doi: 10.1002/ps.8150

Products & Services: Proteins, Expression, Isolation and Analysis

IGFBP1a is a nutrient deficient response factor that can inhibit fish reproduction through the hypothalamus-pituitary-ovary axis†

Authors: Wei Li, Hangyu Li, Qiongyao Hu, Linlin Wang, Zhan Yin, Guangfu Hu

Journal: Biol Reprod

PubMed ID: 38374691

Doi: 10.1093/biolre/ioae009

Products & Services: Gene Synthesis

Effector enrichment by Candidatus Liberibacter promotes Diaphorina citri feeding via Jasmonic acid pathway suppression

Authors: Hao Liu, Bin Deng, Feng-Hao Chen, Jia-Qi Suo, Ge-Cheng Ouyang, Hui-Lin Lu, Da-Song Chen, Xiang Meng

Journal: Pest Manag Sci

PubMed ID: 38554028

Doi: 10.1002/ps.8107

Products & Services: Proteins, Expression, Isolation and Analysis

Multiplexed gene editing in citrus by using a multi-intron containing Cas9 gene

Authors: Poulami Sarkar, Jorge Santiago Vazquez, Mingxi Zhou, Amit Levy, Zhonglin Mou, Vladimir Orbović

Journal: Transgenic Res

PubMed ID: 38564120

Doi: 10.1007/s11248-024-00380-2

Artificial Extracellular Vesicles Generated from T Cells Using Different Induction Techniques

Authors: Ekaterina A Zmievskaya, Sabir A Mukhametshin, Irina A Ganeeva, Elvina M Gilyazova, Elvira T Siraeva, Marianna P Kutyreva, Artur A Khannanov, Youyong Yuan, Emil R Bulatov

Journal: Biomedicines

PubMed ID: 38672273

Doi: 10.3390/biomedicines12040919

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Barley yellow dwarf virus-GAV 17K protein disrupts thiamine biosynthesis to facilitate viral infection in plants

Authors: Xiaoyu Han, Xue Yang, Siyu Chen, He Wang, Xiaomin Liu, Daowen Wang, Jin Yang, Linlin Chen, Bingjian Sun, Honglian Li, Yan Shi

Journal: Plant J

PubMed ID: 38635415

Doi: 10.1111/tpj.16772

Products & Services: Proteins, Expression, Isolation and Analysis

Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase

Authors: Kristen A Baltgalvis, Kelsey N Lamb, Kent T Symons, Chu-Chiao Wu, Melissa A Hoffman, Aaron N Snead, Xiaodan Song, Thomas Glaza, Shota Kikuchi, Jason C Green, Donald C Rogness, Betty Lam, Maria E Rodriguez-Aguirre, David R Woody, Christie L Eissler, Socorro Rodiles, Seth M Negron, Steffen M Bernard, Eileen Tran, Jonathan Pollock, Ali Tabatabaei, Victor Contreras, Heather N Williams, Martha K Pastuszka, John J Sigler, Piergiorgio Pettazzoni, Markus G Rudolph, Moritz Classen, Doris Brugger, Christopher Claiborne, Jean-Marc Plancher, Isabel Cuartas, Joan Seoane, Laurence E Burgess, Robert T Abraham, David S Weinstein, Gabriel M Simon, Matthew P Patricelli, Todd M Kinsella

Journal: Nature

PubMed ID: 38658751

Doi: 10.1038/s41586-024-07318-y

Products & Services: Recombinant Proteins

MSC-derived small extracellular vesicles mitigate diabetic retinopathy by stabilizing Nrf2 through miR-143-3p-mediated inhibition of neddylation

Authors: Yueqin Chen, Jun Tong, Cong Liu, Chang He, Jinjin Xiang, Genhong Yao, Huayong Zhang, Zhenggao Xie

Journal: Free Radic Biol Med

PubMed ID: 38604315

Doi: 10.1016/j.freeradbiomed.2024.04.216

Products & Services: Molecular Biology Reagents

High mobility group box 1 mediates inflammatory responses in malignant peritoneal mesothelioma

Authors: Lianfen Wang, Xuesong Wang, Ningning Sun, Weili Liu

Journal: Int Immunopharmacol

PubMed ID: 38613884

Doi: 10.1016/j.intimp.2024.112039

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Saccharomyces cerevisiae cellular engineering for the production of FAME biodiesel

Authors: Laiyou Wang, Bingbing Liu, Qingshan Meng, Chunchun Yang, Yiyi Hu, Chunyan Wang, Pengyu Wu, Chen Ruan, Wenhuan Li, Shuang Cheng, Shuxian Guo

Journal: AMB Express

PubMed ID: 38658521

Doi: 10.1186/s13568-024-01702-7

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Structural basis of human Na15 gating mechanisms

Authors: Krishna Chinthalapudi, Rupam Biswas, Ana López-Serrano, Hsiang-Ling Huang, Angelina Ramirez-Navarro, Giovanna Grandinetti, Sarah Heissler, Isabelle Deschênes

Journal: Res Sq

PubMed ID: 38659812

Doi: 10.21203/rs.3.rs-3985999/v1

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Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy

Authors: Madison A Ward, Janakiram R Vangala, Hatem Elif Kamber Kaya, Holly A Byers, Nayyerehalsadat Hosseini, Antonio Diaz, Ana Maria Cuervo, Susmita Kaushik, Senthil K Radhakrishnan

Journal: J Cell Biol

PubMed ID: 38656405

Doi: 10.1083/jcb.202306150

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Broadly neutralizing antibodies against emerging delta-coronaviruses

Authors: Megi Rexhepaj, Young-Jun Park, Lisa Perruzza, Daniel Asarnow, Mathew Mccallum, Katja Culap, Christian Saliba, Giada Leoni, Alessio Balmelli, Courtney N Yoshiyama, Miles S Dickinson, Joel Quispe, Jack Taylor Brown, M Alejandra Tortorici, Kaitlin R Sprouse, Ashley L Taylor, Tyler N Starr, Davide Corti, Fabio Benigni, David Veesler

Journal: biorxiv

PubMed ID: 38617231

Doi: 10.1101/2024.03.27.586411

Products & Services: Proteins, Expression, Isolation and Analysis

Elucidation of genes enhancing natural product biosynthesis through co-evolution analysis

Authors: Xinran Wang, Ningxin Chen, Pablo Cruz-Morales, Biming Zhong, Yangming Zhang, Jian Wang, Yifan Xiao, Xinnan Fu, Yang Lin, Suneil Acharya, Zhibo Li, Huaxiang Deng, Yuhui Sun, Linquan Bai, Xiaoyu Tang, Jay D Keasling, Xiaozhou Luo

Journal: Nat Metab

PubMed ID: 38609677

Doi: 10.1038/s42255-024-01024-9

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Pharmacology of PACAP and VIP receptors in the spinal cord highlights the importance of the PAC receptor

Authors: Zoe Tasma, Tayla A Rees, Song Guo, Sheryl Tan, Simon J O'Carroll, Richard L M Faull, Maurice A Curtis, Sarah L Christensen, Debbie L Hay, Christopher S Walker

Journal: Br J Pharmacol

PubMed ID: 38616050

Doi: 10.1111/bph.16376

Products & Services: Proteins, Expression, Isolation and Analysis

Probing altered receptor specificities of antigenically drifting human H3N2 viruses by chemoenzymatic synthesis, NMR, and modeling

Authors: Luca Unione, Augustinus N A Ammerlaan, Gerlof P Bosman, Elif Uslu, Ruonan Liang, Frederik Broszeit, Roosmarijn van der Woude, Yanyan Liu, Shengzhou Ma, Lin Liu, Marcos Gómez-Redondo, Iris A Bermejo, Pablo Valverde, Tammo Diercks, Ana Ardá, Robert P de Vries, Geert-Jan Boons

Journal: Nat Commun

PubMed ID: 38582892

Doi: 10.1038/s41467-024-47344-y

Products & Services: Proteins, Expression, Isolation and Analysis

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