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Shrimp injection with dsRNA targeting the microsporidian EHP polar tube protein reduces internal and external parasite amplification
Authors: Satika Yuanlae, Tharinthon Prasartset, Onrapak Reamtong, Natthinee Munkongwongsiri, Muthita Panphloi, Thanchanok Preechakul, Rungkarn Suebsing, Siripong Thitamadee, Anuphap Prachumwat, Ornchuma Itsathitphaisarn, Suparat Taengchaiyaphum, Chanadda Kasamechotchung
Journal: Sci Rep
PubMed ID: 38413745
Doi: 10.1038/s41598-024-55400-2
Products & Services: Molecular Biology Reagents   
SARS-CoV-2 targets ribosomal RNA biogenesis
Authors: V Talya Yerlici, Audrey Astori, Nevraj S Kejiou, Chris A Jordan, Negin Khosraviani, Janet N Y Chan, Razqallah Hakem, Brian Raught, Alexander F Palazzo, Karim Mekhail
Journal: Cell Rep
PubMed ID: 38427561
Doi: 10.1016/j.celrep.2024.113891
Engineering recombinant replication-competent bluetongue viruses expressing reporter genes for and non-invasive studies
Authors: Sergio Utrilla-Trigo, Luis Jiménez-Cabello, Alejandro Marín-López, Miguel Illescas-Amo, Germán Andrés, Eva Calvo-Pinilla, Gema Lorenzo, Piet A van Rijn, Javier Ortego, Aitor Nogales
Journal: Microbiol Spectr
PubMed ID: 38353566
Doi: 10.1128/spectrum.02493-23
Products & Services: Molecular Biology Reagents   
Rapid Decline of SARS-CoV-2 Viral Load in Single vs Double-Dose (Short-Interval <6 Weeks) ChAdOx nCoV-19 Vaccinated Health-Care Workers
Authors: Arnab Ghosh, Poonam Kanta, Manisha Ramola, Ritin Mohindra, Kapil Goyal, Roop Kishore, Vikas Suri, P V M Lakshmi, Chanderkanta Chauhan, Manisha Sharma, Partha Rakshit, Kalaiarasan Ponnusamy, Tanzin Dikid, Mini P Singh
Journal: Curr Microbiol
PubMed ID: 38353761
Doi: 10.1007/s00284-023-03603-7
Products & Services: Serology SARS-Cov-2 detection kits   
Site-Directed Mutagenesis of VvCYP76F14 (Cytochrome P450) Unveils Its Potential for Selection in Wine Grape Varieties Linked to the Development of Wine Bouquet
Authors: Bin Peng, Jianguo Ran, Yiyang Li, Meiling Tang, Huilin Xiao, Shengpeng Shi, Youzheng Ning, Adeeba Dark, Jin Li, Xueqiang Guan, Zhizhong Song
Journal: J Agric Food Chem
PubMed ID: 38334101
Doi: 10.1021/acs.jafc.3c09083
Products & Services: Gene Synthesis   
Applying valency-based immuno-selection to generate broadly cross-reactive antibodies against influenza hemagglutinins
Authors: Daniëla Maria Hinke, Ane Marie Anderson, Kirankumar Katta, Marlene Fyrstenberg Laursen, Demo Yemane Tesfaye, Ina Charlotta Werninghaus, Davide Angeletti, Gunnveig Grødeland, Bjarne Bogen, Ranveig Braathen
Journal: Nat Commun
PubMed ID: 38346952
Doi: 10.1038/s41467-024-44889-w
Products & Services: Catalog Peptides   
Expression of GPX4 by oncolytic vaccinia virus can significantly enhance CD8T cell function and its impact against pancreatic ductal adenocarcinoma
Authors: Wei Wei, Linqing Tian, Xiaoyan Zheng, Lei Zhong, Yuan Chen, Hui Dong, Guibing Zhang, Shibing Wang, Xiangmin Tong
Journal: Oncoimmunology
PubMed ID: 38419758
Doi: 10.1080/2162402X.2024.2322173
Products & Services: PCR Cloning and Subcloning   
Advances and Challenges in SARS-CoV-2 Detection: A Review of Molecular and Serological Technologies
Authors:
Journal: Diagnostics (Basel)
PubMed ID: 38472991
Doi: 10.3390/diagnostics14050519
Residues within the LptC transmembrane helix are critical for Escherichia coli LptB FG ATPase regulation
Authors: Nicholas P Cina, Dara W Frank, Candice S Klug
Journal: Protein Sci
PubMed ID: 38131105
Doi: 10.1002/pro.4879
Evaluation of the therapeutic effect of a novel bacteriophage in the healing process of infected wounds with Klebsiella pneumoniae in mice
Authors: Fatemeh Zeynali Kelishomi, Farhad Nikkhahi, Samira Amereh, Fatemeh Ghayyaz, Seyed Mahmoud Amin Marashi, Amir Javadi, Gholamhassan Shahbazi, Mohadeseh Khakpour
Journal: J Glob Antimicrob Resist
PubMed ID: 38307250
Doi: 10.1016/j.jgar.2024.01.018
Products & Services: Molecular Biology Reagents   
Structural and functional comparisons of salivary α-glucosidases from the mosquito vectors Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus
Authors: Adeline E Williams, Apostolos G Gittis, Karina Botello, Phillip Cruz, Ines Martin-Martin, Paola Carolina Valenzuela Leon, Benjamin Sumner, Brian Bonilla, Eric Calvo
Journal: Insect Biochem Mol Biol
PubMed ID: 38428508
Doi: 10.1016/j.ibmb.2024.104097
Aberrant Upregulation of RUNX3 Activates Developmental Genes to Drive Metastasis in Gastric Cancer
Authors: Kazuto Suda, Atsushi Okabe, Junichi Matsuo, Linda Shyue Huey Chuang, Ying Li, Nawaphat Jangphattananont, Naing Naing Mon, Khine Nyein Myint, Akihiro Yamamura, Jimmy Bok-Yan So, Dominic Chih-Cheng Voon, Henry Yang, Khay Guan Yeoh, Atsushi Kaneda, Yoshiaki Ito
Journal: Cancer Res Commun
PubMed ID: 38240752
Doi: 10.1158/2767-9764.CRC-22-0165
Products & Services: Custom DNA/RNA Oligos   
The catalytic action of human d-lactate dehydrogenase is severely inhibited by oxalate and is impaired by mutations triggering d-lactate acidosis
Authors: Alessandra Stefan, Alberto Mucchi, Alejandro Hochkoeppler
Journal: Arch Biochem Biophys
PubMed ID: 38373542
Doi: 10.1016/j.abb.2024.109932
Products & Services: Mutagenesis Services   
Development and characterization of DIA 123, a fully human intact anti-CEACAM1 monoclonal antibody
Authors: Michela Centonze, Valentina Fiori, Maciej Kujawski, Lin Li, Patty Wong, Lindsay Williams, Tomas Di Mambro, Sabrina Dominici, Angelo Sparti, John E Shively, Mauro Magnani
Journal: PLoS ONE
PubMed ID: 38346003
Doi: 10.1371/journal.pone.0295345
Products & Services: Molecular Biology Reagents   
Cloning and phylogenetic analysis of N protein gene from Rift Valley Fever Virus (RVFV)
Authors: Ahmed Mohamed Hassan, Arwa Ahmed Zehairy, Al-Judaibi Awatif Abid, Sayed Sartaj Sohrab, Ibraheem Azhar Esam
Journal: Bioinformation
PubMed ID: 38497067
Doi: 10.6026/973206300200091
Products & Services: Molecular Biology Reagents   
Graphene Quantum Dots (GQD)-Mediated dsRNA Delivery for the Control of Fusarium Head Blight Disease in Wheat
Authors: Binod Gyawali, Rahim Rahimi, Houshang Alizadeh, Mohsen Mohammadi
Journal: ACS Appl Bio Mater
PubMed ID: 38422985
Doi: 10.1021/acsabm.3c00972
Products & Services: Molecular Biology Reagents   
Ebselen and TPI-1, as RecG helicase inhibitors, potently enhance the susceptibility of Pseudomonas aeruginosa to DNA damage agents
Authors: Longheng Li, Binbin Guo, Lin Dai, Chun Liu, Zhonghui Lin
Journal: Biochem Pharmacol
PubMed ID: 38354956
Doi: 10.1016/j.bcp.2024.116051
Products & Services: Molecular Biology Reagents   
miR-30e-5p regulates leukemia stem cell self-renewal through the Cyb561/ROS signaling pathway
Authors: Yanwen Ge, Mei Hong, Yu Zhang, Jiachen Wang, Lei Li, Hongkai Zhu, Yue Sheng, Wen-Shu Wu, Zhonghui Zhang
Journal: Haematologica
PubMed ID: 37584287
Doi: 10.3324/haematol.2023.282837
Products & Services: Recombinant Proteins   
Development, validation and application of an ion-pair reversed-phase liquid chromatography-tandem mass spectrometry method for the quantification of nusinersen
Authors: Xiao Zhang, Chunjie Sha, Wei Zhang, Fengjuan Zhao, Mingli Zhu, Guangyi Leng, Wanhui Liu
Journal: Bioanalysis
PubMed ID: 38334103
Doi: 10.4155/bio-2023-0218
Products & Services: Custom DNA/RNA Oligos   
PDGFRβ-Antagonistic Affibody-Mediated Tumor-Targeted Tumor Necrosis Factor-Alpha for Enhanced Radiotherapy in Lung Cancer
Authors: Xiaohui Tang, Jie Chen, Zhenxiong Zhao, Jie Liu, Ranfei Yu, Kunlong Zhao, Fei Wang, Yang Li, Baoqing Tian, Dandan Yuan, Yuguo Liu, Qing Fan
Journal: Mol Pharm
PubMed ID: 38364870
Doi: 10.1021/acs.molpharmaceut.3c00869
Evaluation of nucleotide MALDI-TOF-MS for the identification of species
Authors: Yelei Zhu, Zhengwei Liu, Lina Peng, Bin Liu, Kunyang Wu, Mingwu Zhang, Xiaomeng Wang, Junhang Pan
Journal: Front Cell Infect Microbiol
PubMed ID: 38379773
Doi: 10.3389/fcimb.2024.1335104
Products & Services: Gene Synthesis   
Multitrait engineering of Hassawi red rice for sustainable cultivation
Authors: Khalid Sedeek, Nahed Mohammed, Yong Zhou, Andrea Zuccolo, Krishnaveni Sanikommu, Sunitha Kantharajappa, Noor Al-Bader, Manal Tashkandi, Rod A Wing, Magdy M Mahfouz
Journal: Plant Sci
PubMed ID: 38325660
Doi: 10.1016/j.plantsci.2024.112018
African swine fever virus pH240R enhances viral replication via inhibition of the type I IFN signaling pathway
Authors: Guangqiang Ye, Zhaoxia Zhang, Xiaohong Liu, Hongyang Liu, Weiye Chen, Chunying Feng, Jiangnan Li, Qiongqiong Zhou, Dongming Zhao, Shuai Zhang, Hefeng Chen, Zhigao Bu, Li Huang, Changjiang Weng
Journal: J Virol
PubMed ID: 38353534
Doi: 10.1128/jvi.01834-23
Products & Services: Custom Vector Construction   
Improvement of Carotenoids' Production by Increasing the Activity of Beta-Carotene Ketolase with Different Strategies
Authors: Qiaomian Zhou, Danqiong Huang, Haihong Yang, Zeyu Hong, Chaogang Wang
Journal: Microorganisms
PubMed ID: 38399781
Doi: 10.3390/microorganisms12020377
Products & Services: Custom Vector Construction   
Effectiveness of a broad-spectrum bivalent mRNA vaccine against SARS-CoV-2 variants in preclinical studies
Authors: Jing Lu, Shudan Tan, Hao Gu, Kunpeng Liu, Wei Huang, Zhaoli Yu, Guoliang Lu, Zihan Wu, Xiaobo Gao, Jinghua Zhao, Zongting Yao, Feng Yi, Yantao Yang, Hu Wang, Xue Hu, Mingqing Lu, Wei Li, Hui Zhou, Hang Yu, Chao Shan, Jinzhong Lin
Journal: Emerg Microbes Infect
PubMed ID: 38377136
Doi: 10.1080/22221751.2024.2321994
Supramolecular self-assembly strategies of natural-based β-lactoglobulin modulating bitter perception of goat milk-derived bioactive peptides
Authors: Rong Zhang, Wei Jia
Journal: J Dairy Sci
PubMed ID: 38310962
Doi: 10.3168/jds.2023-24386
Products & Services: Catalog Peptides   
Atypical Plant miRNA cal-miR2911: Robust Stability against Food Digestion and Specific Promoting Effect on in Mice
Authors: Qin Xu, Jianing Wang, Yi Zhang, Ying Li, Xinshu Qin, Yirao Xin, Yinglei Li, Ke Xu, Xingbin Yang, Xingyu Wang
Journal: J Agric Food Chem
PubMed ID: 38393993
Doi: 10.1021/acs.jafc.3c09511
Products & Services: Gene Synthesis   
Using for High-Yield Production of Challenging Expression Targets and for Protein Perdeuteration
Authors: Natalia Mojica, Flore Kersten, Mateu Montserrat-Canals, G Robb Huhn Iii, Abelone M Tislevoll, Gabriele Cordara, Ken Teter, Ute Krengel
Journal: Biochemistry
PubMed ID: 38359344
Doi: 10.1021/acs.biochem.3c00612
Products & Services: Catalog Peptides   
CRISPR Ribonucleoprotein-Mediated Precise Editing of Multiple Genes in Porcine Fibroblasts
Authors: Xiaochen Guo, Chang Liu, Yunjing Zhao, Chaoqian Jiang, Junxue Jin, Zhonghua Liu, Yanshuang Mu
Journal: Animals (Basel)
PubMed ID: 38396618
Doi: 10.3390/ani14040650
Products & Services: Gene Synthesis   
Vaccine Based on Recombinant Fusion Protein Combining Hepatitis B Virus PreS with SARS-CoV-2 Wild-Type- and Omicron-Derived Receptor Binding Domain Strongly Induces Omicron-Neutralizing Antibodies in a Murine Model
Authors: Pia Gattinger, Bernhard Kratzer, Al Nasar Ahmed Sehgal, Anna Ohradanova-Repic, Laura Gebetsberger, Gabor Tajti, Margarete Focke-Tejkl, Mirjam Schaar, Verena Fuhrmann, Lukas Petrowitsch, Walter Keller, Sandra Högler, Hannes Stockinger, Winfried F Pickl, Rudolf Valenta
Journal: Vaccines (Basel)
PubMed ID: 38543863
Doi: 10.3390/vaccines12030229
Products & Services: Recombinant Proteins   
NK-92MI Cells Engineered with Anti-claudin-6 Chimeric Antigen Receptors in Immunotherapy for Ovarian Cancer
Authors: Junping Li, Hong Hu, Hui Lian, Shuo Yang, Manting Liu, Jinping He, Bihui Cao, Dongni Chen, Yuling Hu, Chen Zhi, Yan Shen, Xiaodie Ye, Bingjia He, Ming Zhao, Weijun Fan, Linfeng Xu, Rom Leidner, Qingde Wu, Lili Yang, Zhenfeng Zhang
Journal: Int J Biol Sci
PubMed ID: 38481806
Doi: 10.7150/ijbs.88539
Products & Services: Gene Synthesis   
NEAT1 repression by MED12 creates chemosensitivity in p53 wild-type breast cancer cells
Authors: Shengjie Zhang, Eui-Jun Kim, Junfeng Huang, Peng Liu, Kristine Donahue, Qinchuan Wang, Yidan Wang, Sean Mcilwain, Ling Xie, Xian Chen, Lingjun Li, Wei Xu
Journal: FEBS J
PubMed ID: 38380720
Doi: 10.1111/febs.17097
Creation of a point-of-care therapeutics sensor using protein engineering, electrochemical sensing and electronic integration
Authors: Rong Cai, Chiagoziem Ngwadom, Ravindra Saxena, Jayashree Soman, Chase Bruggeman, David P Hickey, Rafael Verduzco, Caroline M Ajo-Franklin
Journal: Nat Commun
PubMed ID: 38402222
Doi: 10.1038/s41467-024-45789-9
Products & Services: Codon Optimization   
Polycomb repression of Hox genes involves spatial feedback but not domain compaction or phase transition
Authors: Sedona Eve Murphy, Alistair Nicol Boettiger
Journal: Nat Genet
PubMed ID: 38361032
Doi: 10.1038/s41588-024-01661-6
Products & Services: Custom DNA/RNA Oligos   
Performance of Three Anti-SARS-CoV-2 Anti-S and One Anti-N Immunoassays for the Monitoring of Immune Status and Vaccine Response
Authors: Y Victoria Zhang, Attila Kumanovics, Joesph Wiencek, Stacy E F Melanson, Tanzy Love, Alan H B Wu, Zhen Zhao, Qing H Meng, David D Koch, Fred S Apple, Caitlin R Ondracek, Robert H Christenson
Journal: Viruses
PubMed ID: 38400067
Doi: 10.3390/v16020292
Products & Services: Mutagenesis Services   
Long noncoding RNA TMPO-AS1 accelerates glycolysis by regulating the miR-1270/PKM2 axis in colorectal cancer
Authors: Yingmin Jin, Aimin Jiang, Liying Sun, Yue Lu
Journal: BMC Cancer
PubMed ID: 38383342
Doi: 10.1186/s12885-024-11964-w
Products & Services: Catalog Peptides   
CD46 and CD59 inhibitors enhance complement-dependent cytotoxicity of anti-CD38 monoclonal antibodies daratumumab and isatuximab in multiple myeloma and other B-cell malignancy cells
Authors: Hongjie Wang, Theo Koob, Jonathan R Fromm, Ajay Gopal, Darrick Carter, André Lieber
Journal: Cancer Biol Ther
PubMed ID: 38361357
Doi: 10.1080/15384047.2024.2314322
Discovery and Characterization of Selective, First-in-Class Inhibitors of Citron Kinase
Authors: Joshua J Maw, Jesse A Coker, Tarun Arya, Christopher M Goins, Dhiraj Sonawane, Sang Hoon Han, Matthew G Rees, Melissa M Ronan, Jennifer A Roth, Nancy S Wang, Hannelore V Heemers, Jonathan D Macdonald, Shaun R Stauffer
Journal: J Med Chem
PubMed ID: 38330278
Doi: 10.1021/acs.jmedchem.3c01807
Products & Services: Custom Vector Construction   
mTOR Regulates Mineralocorticoid Receptor Transcriptional Activity by ULK1-Dependent and -Independent Mechanisms
Authors: Yusuf Ali, Celso E Gomez-Sanchez, Maria Plonczynski, Aniko Naray-Fejes-Toth, Geza Fejes-Toth, Elise P Gomez-Sanchez
Journal: Endocrinology
PubMed ID: 38325289
Doi: 10.1210/endocr/bqae015
Exploring the immunogenicity of Rv2201-519: A T-cell epitope-based antigen derived from Mycobacterium tuberculosis AsnB with implications for tuberculosis infection detection and vaccine development
Authors: Xiuli Luan, Xueting Fan, Guilian Li, Mchao Li, Na Li, Yuhan Yan, Xiuqin Zhao, Haican Liu, Kanglin Wan
Journal: Int Immunopharmacol
PubMed ID: 38342063
Doi: 10.1016/j.intimp.2024.111542
Products & Services: Molecular Biology Reagents   
Discovery of Two Novel Immunoepitopes and Development of Peptide-based Sarcoidosis Immunoassay
Authors: Changya Peng , Jaya Talreja , Brennen Steinbauer , Kazuhiko Shinki , Laura L Koth , Lobelia Samavati
Journal: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
PubMed ID: 38385694
Doi: 10.1164/rccm.202306-1054OC
Products & Services: Peptide Synthesis   Polyclonal Antibody Services   
An Antioxidative and Active Shrinkage Hydrogel Integratedly Promotes Re-Epithelization and Skin Constriction for Enhancing Wound Closure
Authors: Jiacheng Sun, Wang Jia, Hedong Qi, Jiawei Huo, Xiaodan Liao, Yuan Xu, Jun Wang, Zihao Sun, Yang Liu, Jingchao Liu, Mingming Zhen, Chunru Wang, Chunli Bai
Journal: Adv Mater
PubMed ID: 38332741
Doi: 10.1002/adma.202312440
Essential functions of Inositol hexakisphosphate (IP6) in Murine Leukemia Virus replication
Authors: Banhi Biswas, Kin Kui Lai, Harrison Bracey, Siddhartha A K Datta, Demetria Harvin, Gregory A Sowd, Christopher Aiken, Alan Rein
Journal: biorxiv
PubMed ID: 38464197
Doi: 10.1101/2024.02.27.581940
Architecture and flexibility of native kinetochores revealed by structural studies utilizing a thermophilic yeast
Authors: Daniel J Barrero, Sithara S Wijeratne, Xiaowei Zhao, Grace F Cunningham, Yan Rui, Christian R Nelson, Arimura Yasuhiro, Hironori Funabiki, Charles L Asbury, Zhiheng Yu, Radhika Subramanian, Sue Biggins
Journal: biorxiv
PubMed ID: 38464254
Doi: 10.1101/2024.02.28.582571
Products & Services: Recombinant Proteins   
Unveiling PET Hydrolase Surface Dynamics through Fluorescence Microscopy
Authors: A P Rennison, A Nousi, P Westh, R Marie, M S Møller
Journal: Chembiochem
PubMed ID: 38224131
Doi: 10.1002/cbic.202300661
Products & Services: Molecular Biology Reagents   
NY-ESO-1-specific T cell receptor-engineered T cells and Tranilast, a TRPV2 antagonist bivalent treatment enhances the killing of esophageal cancer: a dual-targeted cancer therapeutic route
Authors: Obed Boadi Amissah, Wenfang Chen, Jean de Dieu Habimana, Yirong Sun, Lihui Lin, Yujie Liu, Ling Wang, Zhaoming Liu, Omar Mukama, Rajesh Basnet, Hohua Liu, Junyi Li, Xuanyan Ding, Lingshuang Lv, Min Chen, Yalin Liang, Rongqi Huang, Zhiyuan Li
Journal: Cancer Cell Int
PubMed ID: 38336680
Doi: 10.1186/s12935-024-03249-w
Products & Services: Catalog Peptides   
CD39 tumor infiltrating T cells from colorectal cancers exhibit dysfunctional phenotype
Authors: Yuan Feng, Xin Xu, Jiaxin Zhang, Christopher Sanderson, Jun Xia, Zhang Bu, Yili Yang, Peng Yang, Zhiliang Lu
Journal: Am J Cancer Res
PubMed ID: 38455401
Doi: 10.62347/IZEN3736
Products & Services: Catalog Peptides   
Exploring the ATG9A interactome uncovers interaction with VPS13A
Authors: Alexander R van Vliet, Harold B J Jefferies, Peter A Faull, Jessica Chadwick, Fairouz Ibrahim, Mark J Skehel, Sharon A Tooze
Journal: J Cell Sci
PubMed ID: 38294121
Doi: 10.1242/jcs.261081
A Direct Comparison of rAAV5 Variants Derived from the Baculovirus Expression System Using LC-MS Workflows Demonstrates Key Differences in Overall Production Yield, Product Quality and Vector Efficiency
Authors: Felipe Guapo, Nicholas Donohue, Lisa Strasser, Stefano Boi, Florian Füssl, Alana Rainbow-Fletcher, Paul Getty, Ian Anderson, Niall Barron, Jonathan Bones
Journal: Int J Mol Sci
PubMed ID: 38474031
Doi: 10.3390/ijms25052785
Products & Services: Codon Optimization   
Seroprevalence of IgM/IgG and Neutralizing Antibodies against SARS-CoV-2 in Unvaccinated Young Adults from Mexico Who Reported Not Having Had a Previous COVID-19 Infection
Authors: Diana Lourdes Padilla-Bórquez, Mónica Guadalupe Matuz-Flores, Jorge Hernández-Bello, Gabriela Athziri Sánchez-Zuno, Samuel García-Arellano, Edith Oregon-Romero, Melva Guadalupe Herrera-Godina, Guillermo González-Estevez, Norma Patricia Adan-Bante, Jesús Alfredo Rosas-Rodríguez, José Francisco Muñoz-Valle
Journal: Can J Infect Dis Med Microbiol
PubMed ID: 38384428
Doi: 10.1155/2024/8871439

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