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AS03 adjuvant enhances the magnitude, persistence, and clonal breadth of memory B cell responses to a plant-based COVID-19 vaccine in humans
Authors: Lilit Grigoryan, Yupeng Feng, Lorenza Bellusci, Lilin Lai, Bushra Wali, Madison Ellis, Meng Yuan, Prabhu S Arunachalam, Mengyun Hu, Sangeeta Kowli, Sheena Gupta, Sofia Maysel-Auslender, Holden T Maecker, Hady Samaha, Nadine Rouphael, Ian A Wilson, Alberto C Moreno, Mehul S Suthar, Surender Khurana, Stéphane Pillet, Nathalie Charland, Brian J Ward, Bali Pulendran
Journal: Science immunology
PubMed ID: 38579013
Doi: 10.1126/sciimmunol.adi8039
Products & Services: Gene Synthesis   
Dbf4-dependent kinase promotes cell cycle controlled resection of DNA double-strand breaks and repair by homologous recombination
Authors: Lorenzo Galanti, Martina Peritore, Robert Gnügge, Elda Cannavo, Johannes Heipke, Maria Dilia Palumbieri, Barbara Steigenberger, Lorraine S Symington, Petr Cejka, Boris Pfander
Journal: Nature Communications
PubMed ID: 38570537
Doi: 10.1038/s41467-024-46951-z
Products & Services: Gene Synthesis   
CoPoP liposomes displaying stabilized clade C HIV-1 Env elicit tier 2 multiclade neutralization in rabbits
Authors: Annemart Koornneef, Kanika Vanshylla, Gijs Hardenberg, Lucy Rutten, Nika M Strokappe, Jeroen Tolboom, Jessica Vreugdenhil, Karin Feddes-de Boer, Aditya Perkasa, Sven Blokland, Judith A Burger, Wei-Chiao Huang, Jonathan F Lovell, Danielle van Manen, Rogier W Sanders, Roland C Zahn, Hanneke Schuitemaker, Johannes P M Langedijk, Frank Wegmann
Journal: Nature Communications
PubMed ID: 38605096
Doi: 10.1038/s41467-024-47492-1
Products & Services: Codon Optimization   
Dual-responsive nanocarriers for efficient cytosolic protein delivery and CRISPR-Cas9 gene therapy of inflammatory skin disorders
Authors: Echuan Tan, Tao Wan, Qi Pan, Jianan Duan, Song Zhang, Ruijue Wang, Peng Gao, Jia Lv, Hui Wang, Dali Li, Yuan Ping, Yiyun Cheng
Journal: SCIENCE ADVANCES
PubMed ID: 38630829
Doi: 10.1126/sciadv.adl4336
Streptococcus pneumoniae endopeptidase O induces trained immunity and confers protection against various pathogenic infections
Authors: Wenlong Xu, Yuan Yuan, Zhaoche Shu, Ting Guo, Bichen Liu, Jiangming Xiao, Lian Li, Yibin Yin, Xuemei Zhang
Journal: Clin Immunol
PubMed ID: 38663493
Doi: 10.1016/j.clim.2024.110226
Products & Services: Molecular Biology Reagents   
P66 is a bacterial mimic of CD47 that binds the anti-phagocytic receptor SIRPα and facilitates macrophage evasion by
Authors: Michal Caspi Tal, Paige S Hansen, Haley A Ogasawara, Qingying Feng, Regan F Volk, Brandon Lee, Sara E Casebeer, Grace S Blacker, Maia Shoham, Sarah D Galloway, Anne L Sapiro, Beth Hayes, Laughing Bear Torrez Dulgeroff, Tal Raveh, Venkata Raveendra Pothineni, Hari-Hara Sk Potula, Jayakumar Rajadas, Effie E Bastounis, Seemay Chou, William H Robinson, Jenifer Coburn, Irving L Weissman, Balyn W Zaro
Journal: biorxiv
PubMed ID: 38746193
Doi: 10.1101/2024.04.29.591704
Regulation by the RNA-binding protein Unkempt at its effector interface
Authors: Kriti Shah, Shiyang He, David J Turner, Joshua Corbo, Khadija Rebbani, Daniel Dominguez, Joseph M Bateman, Sihem Cheloufi, Cátia Igreja, Eugene Valkov, Jernej Murn
Journal: Nat Commun
PubMed ID: 38605040
Doi: 10.1038/s41467-024-47449-4
Products & Services: Catalog Peptides   
Author Correction: Fuzzy recognition by the prokaryotic transcription factor HigA2 from Vibrio cholerae
Authors: San Hadži, Zala Živič, Matic Kovačič, Uroš Zavrtanik, Sarah Haesaerts, Daniel Charlier, Janez Plavec, Alexander N Volkov, Jurij Lah, Remy Loris
Journal: Nat Commun
PubMed ID: 38664458
Doi: 10.1038/s41467-024-47946-6
Products & Services: Custom Vector Construction   
A selective Fibroblast Growth Factor Receptor 1/2 PROTAC degrader with 1 antitumor activity
Authors: Ying Kong , Xinyue Zhao , Zhaofu Wang , Siqi Yuan , Sheng Chen , Shidi Lou , Shichao Ma , Yunfeng Li , Xinghao Wang , Yangfeng Ge , Guobin Li , Hongbing Yang , Mengxi Zhao , Dandan Li , Hailong Zhang , Wenfu Tan , Juan Wang
Journal: Molecular cancer therapeutics
PubMed ID: 38647531
Doi: 10.1158/1535-7163.MCT-23-0719
Products & Services: Gene Synthesis   
Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system
Authors: Lijie Guo, Pingping Huang, Zhaoxing Li, Young-Cheul Shin, Purui Yan, Meiling Lu, Meirong Chen, Yibei Xiao
Journal: Nat Chem Biol
PubMed ID: 37932527
Doi: 10.1038/s41589-023-01478-0
Products & Services: Molecular Biology Reagents   Gene Synthesis   

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