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Glycosyl transferase GT2 genes mediate the biosynthesis of an unusual (1,3;1,4)-β-glucan exopolysaccharide in the bacterium Sarcina ventriculi

Authors: Edwin R Lampugnani, Kris Ford, Yin Ying Ho, Allison van de Meene, Jelle Lahnstein, Hwei-Ting Tan, Rachel A Burton, Geoffrey B Fincher, Thomas Shafee, Antony Bacic, Jochen Zimmer, Xiaohui Xing, Vincent Bulone, Monika S Doblin, Eric M Roberts

Journal: Mol Microbiol

PubMed ID: 38750617

Doi: 10.1111/mmi.15276

Products & Services: DNA Sequencing

Vitamin E alleviates chlorpyrifos induced glutathione depletion, lipid peroxidation and iron accumulation to inhibit ferroptosis in hepatocytes and mitigate toxicity in zebrafish

Authors: Poulami Sen Gupta, Subrata Karmakar, Ipsita Biswas, Jahnabi Ghosal, Ankur Banerjee, Soumen Roy, Deba Prasad Mandal, Shamee Bhattacharjee

Journal: Chemosphere

PubMed ID: 38735493

Doi: 10.1016/j.chemosphere.2024.142252

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Targeting Prohibitin 2-Hu-Hsp70A1A complex as a unique approach towards malaria vaccine development

Authors: Manisha Marothia, Ankita Behl, Preeti Maurya, Monika Saini, Rumaisha Shoaib, Swati Garg, Geeta Kumari, Shreeja Biswas, Akshay Munjal, Sakshi Anand, Amandeep Kaur Kahlon, Pragya Gupta, Saurav Biswas, Bidhan Goswami, Haider Thaer Abdulhameed Almuqdadi, Ipsita Pal Bhowmick, Maxim Shevtsov, Sivaprakash Ramalingam, Anand Ranganathan, Shailja Singh

Journal: iScience

PubMed ID: 38812541

Doi: 10.1016/j.isci.2024.109918

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A 3D spheroid model of quadruple cell co-culture with improved liver functions for hepatotoxicity prediction

Authors: Baiyang Sun, Zihe Liang, Yupeng Wang, Yue Yu, Xiaobing Zhou, Xingchao Geng, Bo Li

Journal: Toxicology

PubMed ID: 38740170

Doi: 10.1016/j.tox.2024.153829

Products & Services: Proteins, Expression, Isolation and Analysis

Structural mechanisms of Tad pilus assembly and its interaction with an RNA virus

Authors: Yuhang Wang, Matthew Theodore, Zhongliang Xing, Utkarsh Narsaria, Zihao Yu, Lanying Zeng, Junjie Zhang

Journal: SCIENCE ADVANCES

PubMed ID: 38701202

Doi: 10.1126/sciadv.adl4450

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TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington’s disease

Authors: Yiyang Qin, Laiqiang Chen, Wenzhen Zhu, Jiahong Song, Jingpan Lin, Yuwei Li, Jiawei Zhang, Xichen Song, Tingting Xing, Tingting Guo, Xuezhi Duan, Yiran Zhang, Eshu Ruan, Qi Wang, Bang Li, Weili Yang , Peng Yin, Xiao-Xin Yan, Shihua Li, Xiao-Jiang Li, Su Yang

Journal: SCIENCE ADVANCES

PubMed ID: 38758800

Doi: 10.1126/sciadv.adl2036

Products & Services: Proteins, Expression, Isolation and Analysis

In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model

Authors: Melisa Benard-Valle, Yessica Wouters, Anne Ljungars, Giang Thi Tuyet Nguyen, Shirin Ahmadi, Tasja Wainani Ebersole, Camilla Holst Dahl, Alid Guadarrama-Martínez, Frederikke Jeppesen, Helena Eriksen, Gibran Rodríguez-Barrera, Kim Boddum, Timothy Patrick Jenkins, Sara Petersen Bjørn, Sanne Schoffelen, Bjørn Gunnar Voldborg, Alejandro Alagón & Andreas Hougaard Laustsen

Journal: Nat Commun

PubMed ID: 38773068

Doi: 10.1038/s41467-024-48539-z

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Development of a Fully Protective Pandemic Avian Influenza Subunit Vaccine in Insect Pupae

Authors: Ana Falcón, Susana Martínez-Pulgarín, Sergi López-Serrano, Edel Reytor, Miguel Cid, Maria Del Carmen Nuñez, Lorena Córdoba, Ayub Darji, José M Escribano

Journal: Viruses

PubMed ID: 38932122

Doi: 10.3390/v16060829

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AAV-mediated Gene Cocktails Enhance Supporting Cell Reprogramming and Hair Cell Regeneration

Authors: Liyan Zhang, Xin Chen, Xinlin Wang, Yinyi Zhou, Yuan Fang, Xingliang Gu, Ziyu Zhang, Qiuhan Sun, Nianci Li, Lei Xu, Fangzhi Tan, Renjie Chai, Jieyu Qi

Journal: Adv Sci (Weinh)

PubMed ID: 38810137

Doi: 10.1002/advs.202304551

Products & Services: Proteins, Expression, Isolation and Analysis

Aβ42 and ROS dual-targeted multifunctional nanocomposite for combination therapy of Alzheimer’s disease

Authors: Liding Zhang , Kai Cao , Jun Xie , Xiaohan Liang , Hui Gong , Qingming Luo , Haiming Luo

Journal: J Nanobiotechnology

PubMed ID: 38783363

Doi: doi.org/10.1186/s12951-024-02543-z

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Quercetin induces itaconic acid-mediated M1/M2 alveolar macrophages polarization in respiratory syncytial virus infection

Authors: Li An , Qianwen Zhai , Keyu Tao , Yingcai Xiong , Weiying Ou , Ziwei Yu , Xingyu Yang , Jianjian Ji , Mengjiang Lu

Journal: Phytomedicine

PubMed ID: 38797031

Doi: 10.1016/j.phymed.2024.155761

Products & Services: Proteins, Expression, Isolation and Analysis

Imaging the dynamics of messenger RNA with a bright and stable green fluorescent RNA

Authors: Fangting Zuo, Li Jiang, Ni Su, Yaqiang Zhang, Bingkun Bao, Limei Wang, Yajie Shi, Huimin Yang, Xinyi Huang, Ruilong Li, Qingmei Zeng, Zhengda Chen, Qiuning Lin, Yingping Zhuang, Yuzheng Zhao, Xianjun Chen, Linyong Zhu & Yi Yang

Journal: nature chemical biology

PubMed ID: 38783134

Doi: 10.1038/s41589-024-01629-x

Products & Services: Single-Stranded DNA Synthesis

Novel Multi-Antigen Orf-Virus-Derived Vaccine Elicits Protective Anti-SARS-CoV-2 Response in Monovalent and Bivalent Formats

Authors: Dominique Julien Burri, Louis Renz, Melanie Mueller, Felix Pagallies, Ute Klinkhardt, Ralf Amann, Madiha Derouazi

Journal: Vaccines (Basel)

PubMed ID: 38793740

Doi: 10.3390/vaccines12050490

Products & Services: Recombinant Proteins

A fluorescence anisotropy-based competition assay to identify inhibitors against ricin and Shiga toxin ribosome interactions

Authors: Arkajyoti Dutta, Zoltan Szekely, Hakan Guven, Xiao-Ping Li, John E McLaughlin, Nilgun E Tumer

Journal: Anal Biochem

PubMed ID: 38825159

Doi: 10.1016/j.ab.2024.115580

Products & Services: Proteins, Expression, Isolation and Analysis

Structural basis of nearest-neighbor cooperativity in the ring-shaped gene regulatory protein TRAP from protein engineering and cryo-EM

Authors: Weicheng Li, Haoyun Yang, Kye Stachowski, Andrew S Norris, Katie Lichtenthal, Skyler Kelly, Paul Gollnick, Vicki H Wysocki, Mark P Foster

Journal: biorxiv

PubMed ID: 38746386

Doi: 10.1101/2024.05.02.592192

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Citrus psorosis virus 24K protein inhibits the processing of miRNA precursors by interacting with components of the biogenesis machinery

Authors: Facundo E Marmisolle, María B Borniego, Damián A Cambiagno, Lucia Gonzalo, María L García, Pablo A Manavella, Carmen Hernández, Carina A Reyes

Journal: Microbiol Spectr

PubMed ID: 38785434

Doi: 10.1128/spectrum.03513-23

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LINE-1 retrotransposons contribute to mouse PV interneuron development

Authors: Gabriela O Bodea, Juan M Botto, Maria E Ferreiro, Francisco J Sanchez-Luque, Jose de Los Rios Barreda, Jay Rasmussen, Muhammed A Rahman, Laura R Fenlon, Natasha Jansz, Carolina Gubert, Patricia Gerdes, Liviu-Gabriel Bodea, Prabha Ajjikuttira, Darwin J Da Costa Guevara, Linda Cumner, Charles C Bell, Peter Kozulin, Victor Billon, Santiago Morell, Marie-Jeanne H C Kempen, Chloe J Love, Karabi Saha, Lucy M Palmer, Adam D Ewing, Dhanisha J Jhaveri, Sandra R Richardson, Anthony J Hannan, Geoffrey J Faulkner

Journal: Nat Neurosci

PubMed ID: 38773348

Doi: 10.1038/s41593-024-01650-2

Products & Services: Molecular Biology Reagents

Multifunctional bispecific nanovesicles targeting SLAMF7 trigger potent antitumor immunity

Authors: Manman Zhu, Yongjian Wu, Tianchuan Zhu, Jian Chen, Zhenxing Chen, Hanxi Ding, Siyi Tan, Jianzhong He, Qi Zeng, Xi Huang

Journal: Cancer Immunol Res

PubMed ID: 38819238

Doi: 10.1158/2326-6066.CIR-23-1102

Products & Services: DNA Sequencing

Anti-HIV Humoral Response Induced by Different Anti-Idiotype Antibody Formats: An In Silico and In Vivo Approach

Authors: Valeria Caputo, Ilaria Negri, Louiza Moudoud, Martina Libera, Luigi Bonizzi, Massimo Clementi, Roberta Antonia Diotti

Journal: Int J Mol Sci

PubMed ID: 38891926

Doi: 10.3390/ijms25115737

Products & Services: Molecular Biology Reagents

Cross-reactivity of hantavirus antibodies after immunization with PUUV antigens

Authors: Layaly Shkair, Diksha Sharma, Shaimaa Hamza, Ekaterina Garanina, Venara Shakirova, Ilsiyar Khaertynova, Maria Markelova, Vera Pavelkina, Albert Rizvanov, Svetlana Khaiboullina, Manoj Baranwal, Ekaterina Martynova

Journal: Biotechnol Appl Biochem

PubMed ID: 38779849

Doi: 10.1002/bab.2604

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Elucidation of the Catalytic Sequence of Dihydroorotate Dehydrogenase B from : Evidence for Accumulation of a Flavin Bisemiquinone State in Catalysis

Authors: Corine O Smith, Graham R Moran

Journal: Biochemistry

PubMed ID: 38691339

Doi: 10.1021/acs.biochem.4c00025

Products & Services: Gene Synthesis

Delivery of endolysin across outer membrane of Gram-negative bacteria using translocation domain of botulinum neurotoxin

Authors: Wonbeom Park, Myungseo Park, Jihwan Chun, Jaehyeon Hwang, Suhyun Kim, Nayoon Choi, Soo Min Kim, SeungJoo Kim, Sangwon Jung, Kwan Soo Ko, Dae-Hyuk Kweon

Journal: Int J Antimicrob Agents

PubMed ID: 38795926

Doi: 10.1016/j.ijantimicag.2024.107216

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Transcriptome Analysis Reveals the Induction of Apoptosis-Related Genes by a Monoclonal Antibody against a New Epitope of CD99 on T-Acute Lymphoblastic Leukemia

Authors: Nuchjira Takheaw, Kamonporn Kotemul, Ratthakorn Chaiwut, Supansa Pata, Witida Laopajon, Kuntalee Rangnoi, Montarop Yamabhai, Watchara Kasinrerk

Journal: Antibodies (Basel)

PubMed ID: 38804310

Doi: 10.3390/antib13020042

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Development of a Plant-Expressed Subunit Vaccine against Brucellosis

Authors: Daria A Rutkowska, Lissinda H Du Plessis, Essa Suleman, Martha M O'Kennedy, Deepak B Thimiri Govinda Raj, Yolandy Lemmer

Journal: Microorganisms

PubMed ID: 38930429

Doi: 10.3390/microorganisms12061047

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Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations

Authors: Jeannette L Tenthorey, Serena Del Banco, Ishrak Ramzan, Hayley Klingenberg, Chang Liu, Michael Emerman, Harmit S Malik

Journal: biorxiv

PubMed ID: 38765965

Doi: 10.1101/2024.05.07.592993

Products & Services: PCR Cloning and Subcloning

Exploring Syndecan-4 and MLP and Their Interaction in Primary Cardiomyocytes and H9c2 Cells

Authors: Thea Parsberg Støle, Marianne Lunde, Katja Gehmlich, Geir Christensen, William E Louch, Cathrine Rein Carlson

Journal: Cells

PubMed ID: 38891079

Doi: 10.3390/cells13110947

Products & Services: Recombinant Proteins

The E3 ubiquitin-protein ligase UHRF1 promotes adipogenesis and limits fibrosis by suppressing GPNMB-mediated TGF-β signaling

Authors: Muneera Vakayil, Aisha Y Madani, Maha V Agha, Yasser Majeed, Shahina Hayat, Shameem Yonuskunju, Yasmin Ali Mohamoud, Joel Malek, Karsten Suhre, Nayef A Mazloum

Journal: Sci Rep

PubMed ID: 38789534

Doi: 10.1038/s41598-024-62508-y

Products & Services: Molecular Biology Reagents

Development of a nucleoside-modified mRNA vaccine against clade 2344b H5 highly pathogenic avian influenza virus

Authors: Colleen Furey, Gabrielle Scher, Naiqing Ye, Lisa Kercher, Jennifer DeBeauchamp, Jeri Carol Crumpton, Trushar Jeevan, Christopher Patton, John Franks, Adam Rubrum, Mohamad-Gabriel Alameh, Steven H Y Fan, Anthony T Phan, Christopher A Hunter, Richard J Webby, Drew Weissman, Scott E Hensley

Journal: Nat Commun

PubMed ID: 38782954

Doi: 10.1038/s41467-024-48555-z

Products & Services: Molecular Biology Reagents

Safety, immunogenicity and efficacy of the self-amplifying mRNA ARCT-154 COVID-19 vaccine: pooled phase 1, 2, 3a and 3b randomized, controlled trials

Authors: Nhân Thị Hồ, Steven G Hughes, Van Thanh Ta, Lân Trọng Phan, Quyết Đỗ, Thượng Vũ Nguyễn, Anh Thị Văn Phạm, Mai Thị Ngọc Đặng, Lượng Viết Nguyễn, Quang Vinh Trịnh, Hùng Ngọc Phạm, Mến Văn Chử, Toàn Trọng Nguyễn, Quang Chấn Lương, Vy Thị Tường Lê, Thắng Văn Nguyễn, Lý-Thi-Lê Trần, Anh Thi Van Luu, Anh Ngoc Nguyen, Nhung-Thi-Hong Nguyen, Hai-Son Vu, Jonathan M Edelman, Suezanne Parker, Brian Sullivan, Sean Sullivan, Qian Ruan, Brenda Clemente, Brian Luk, Kelly Lindert, Dina Berdieva, Kat Murphy, Rose Sekulovich, Benjamin Greener, Igor Smolenov, Pad Chivukula, Vân Thu Nguyễn, Xuan-Hung Nguyen

Journal: Nat Commun

PubMed ID: 38744844

Doi: 10.1038/s41467-024-47905-1

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Substrate Affinity Is Not Crucial for Therapeutic L-Asparaginases: Antileukemic Activity of Novel Bacterial Enzymes

Authors: Anna Ściuk, Kinga Wątor, Izabela Staroń, Paulina Worsztynowicz, Kinga Pokrywka, Joanna Sliwiak, Marta Kilichowska, Kamila Pietruszewska, Zofia Mazurek, Anna Skalniak, Krzysztof Lewandowski, Mariusz Jaskolski, Joanna I Loch, Marcin Surmiak

Journal: Molecules

PubMed ID: 38792133

Doi: 10.3390/molecules29102272

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Biophysical insights into the dimer formation of human Sirtuin 2

Authors: Noa Suzuki, Tsuyoshi Konuma, Takahisa Ikegami, Satoko Akashi

Journal: Protein Sci

PubMed ID: 38647411

Doi: 10.1002/pro.4994

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A Piecewise Design Approach to Engineering a Miniature ACE2 Mimic to Bind SARS-CoV-2

Authors: Yashavantha L Vishweshwaraiah, Brianna Hnath, Jian Wang, Morgan Chandler, Arnab Mukherjee, Neela H Yennawar, Squire J Booker, Kirill A Afonin, Nikolay V Dokholyan

Journal: ACS Appl Bio Mater

PubMed ID: 38700999

Doi: 10.1021/acsabm.4c00222

Products & Services: Proteins, Expression, Isolation and Analysis

Combined effect of SAR-endolysin LysKpV475 with polymyxin B and bacteriophage phSE-5

Authors: Marco Gontijo, Mateus Pereira Teles, Hugo Martins Correia, Genesy Pérez Jorge, Isabella Carolina Rodrigues Santos Goes, Anthony Jhoao Fasabi Flores, Márcia Braz, Lucas de Moraes Ceseti, Priscila Zonzini Ramos, Ivan Rosa E Silva, Pedro Marcus Pereira Vidigal, Jörg Kobarg, Rafael Miguez Couñago, Cristina Elisa Alvarez-Martinez, Carla Pereira, Carmen S R Freire, Adelaide Almeida, Marcelo Brocchi

Journal: Microbiology (Reading)

PubMed ID: 38739436

Doi: 10.1099/mic.0.001462

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Construction and in vitro characterisation of virus-vectored immunocontraceptive candidates derived from felid alphaherpesvirus 1

Authors: Ellen Cottingham, Thurid Johnstone, Paola K Vaz, Carol A Hartley, Joanne M Devlin

Journal: Vaccine

PubMed ID: 38824082

Doi: 10.1016/j.vaccine.2024.05.047

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Amplifiable protein identification via residue-resolved barcoding and composition code counting

Authors: Weiming Guo , Yuan Liu , Yu Han , Huan Tang , Xinyuan Fan , Chu Wang , Peng R Chen

Journal: National Science Review

PubMed ID: 39055168

Doi: 10.1093/nsr/nwae183

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A converged ubiquitin‐proteasome pathway for the degradation of TOC and TOM tail‐anchored receptors

Authors: Meijing Yang , Shuai Chen , Shey-Li Lim , Lang Yang , Jia Yi Zhong , Koon Chuen Chan , Zhizhu Zhao , Kam-Bo Wong , Junqi Wang , Boon Leong Lim

Journal: Journal of integrative plant biology

PubMed ID: 38501483

Doi: doi.org/10.1111/jipb.13645

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Impact of N-Glycosylation on Protein Structure and Dynamics Linked to Enzymatic C–H Activation in the M. oryzae Lipoxygenase

Authors: Chris Whittington, Ajay Sharma, S Gage Hill, Anthony T Iavarone, Brian M Hoffman, Adam R Offenbacher

Journal: Biochemistry

PubMed ID: 38690768

Doi: 10.1021/acs.biochem.4c00109

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Manganese-dependent transcription regulation by MntR and PerR in Thermus thermophilus HB8

Authors: John K Barrows, Kamya A Stubbs, Irina F Padilla-Montoya, Thomas C Leeper, Michael W Van Dyke

Journal: Mol Microbiol

PubMed ID: 38735869

Products & Services: Nucleic Acid Purification & Analysis

Delineating organizational principles of the endogenous L-A virus by cryo-EM and computational analysis of native cell extracts

Authors: Lisa Schmidt, Christian Tüting, Fotis L Kyrilis, Farzad Hamdi, Dmitry A Semchonok, Gerd Hause, Annette Meister, Christian Ihling, Milton T Stubbs, Andrea Sinz, Panagiotis L Kastritis

Journal: Commun Biol

PubMed ID: 38730276

Doi: 10.1038/s42003-024-06204-7

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TALEN-mediated homologous-recombination-based fibroin light chain in-fusion expression system in

Authors: Shihua Yu, Huoqing Zheng, Xiaogang Ye, Xiangping Dai, Xinqiu Wang, Shuo Zhao, Xiaoyan Dai, Boxiong Zhong

Journal: Front Bioeng Biotechnol

PubMed ID: 38832132

Doi: 10.3389/fbioe.2024.1399629

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Identification of Fibrinogen as a Plasma Protein Binding Partner for Lecanemab Biosimilar IgG: Implications for Alzheimer's Disease Therapy

Authors: Jean-Pierre Bellier, Andrea Roman, Caitlyn Christiano, Juliana Au Anzai, Stephanie Moreno, Emily C Campbell, Lucas Godwin, Amy Li, Alan Chen, Sarah M Alan, Adriana Saba, Han Bin Yoo, Hyun-Sik Yang, Jasmeer P Chhatwal, Dennis J Selkoe, Lei Liu

Journal: biorxiv

PubMed ID: 38746192

Doi: 10.1101/2024.05.01.591892

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Iguratimod suppresses plasma cell differentiation and ameliorates experimental Sjögren's syndrome in mice by promoting TEC kinase degradation

Authors: Ya-Qi Yang, Yi-Jun Liu, Wen-Xuan Qiao, Wei Jin, Shun-Wei Zhu, Yu-Xi Yan, Qiong Luo, Qiang Xu

Journal: Acta Pharmacol Sin

PubMed ID: 38744938

Doi: 10.1038/s41401-024-01288-7

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A ferritin nanoparticle vaccine based on the hemagglutinin extracellular domain of swine influenza A (H1N1) virus elicits protective immune responses in mice and pigs

Authors: Pan Tang, Enhui Cui, Jinghua Cheng, Benqiang Li, Jie Tao, Ying Shi, Jiajie Jiao, Enqi Du, Jingyu Wang, Huili Liu

Journal: Front Immunol

PubMed ID: 38835763

Doi: 10.3389/fimmu.2024.1361323

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Radiation-primed TGF-β trapping by engineered extracellular vesicles for targeted glioblastoma therapy

Authors: Ruyu Liang, Hongyu Lu, Haifeng Zhu, Gaofeng Liang, Junxia Zhang, Jun Gao, Tian Tian

Journal: J Control Release

PubMed ID: 38740092

Doi: 10.1016/j.jconrel.2024.05.022

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Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase

Authors: Garrett L Schey, Emily R Hildebrandt, You Wang, Safwan Diwan, Holly A Passetti, Gavin W Potts, Andrea M Sprague-Getsy, Ethan R Leoni, Taylor S Kuebler, Yuk Y Sham, James L Hougland, Lorena S Beese, Walter K Schmidt, Mark D Distefano

Journal: Int J Mol Sci

PubMed ID: 38791363

Doi: 10.3390/ijms25105324

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Production of VP3-only virus-like particles of Adeno-associated virus 2 in E coli cells

Authors: Chengyu Fu, Shruthi Gobbooru, Ashley T Martino, Woon-Kai Low

Journal: Protein Expr Purif

PubMed ID: 38754753

Doi: 10.1016/j.pep.2024.106502

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Scanning mutagenesis of the voltage-gated sodium channel Na12 using base editing

Authors: Juan Lorenzo B Pablo, Savannah L Cornett, Lei A Wang, Sooyeon Jo, Tobias Brünger, Nikita Budnik, Mudra Hegde, Jean-Marc DeKeyser, Christopher H Thompson, John G Doench, Dennis Lal, Alfred L George, Jen Q Pan

Journal: Cell Rep

PubMed ID: 38823014

Doi: 10.1016/j.celrep.2024.114327

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Automated characterization and analysis of expression compatibility between regulatory sequences and metabolic genes in

Authors: Xiao Wen, Jiawei Lin, Chunhe Yang, Ying Li, Haijiao Cheng, Ye Liu, Yue Zhang, Hongwu Ma, Yufeng Mao, Xiaoping Liao, Meng Wang

Journal: Synth Syst Biotechnol

PubMed ID: 38817827

Doi: 10.1016/j.synbio.2024.05.010

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The pioneer transcription factor Zelda facilitates the exit from regeneration and restoration of patterning in

Authors: Anish Bose, Keaton Schuster, Chandril Kodali, Surabhi Sonam, Rachel Smith-Bolton

Journal: biorxiv

PubMed ID: 38854062

Doi: 10.1101/2024.05.30.596672

Products & Services: Proteins, Expression, Isolation and Analysis

Optimization of quenched fluorescent peptide substrates of SARS-CoV-2 3CL main protease (Mpro) from proteomic identification of P6-P6' active site specificity

Authors: Hugo Cesar Ramos de Jesus, Nestor Solis, Yoan Machado, Isabel Pablos, Peter A Bell, Reinhild Kappelhoff, Peter M Grin, Carlos A Sorgi, Georgina S Butler, Christopher M Overall

Journal: J Virol

PubMed ID: 38742901

Doi: 10.1128/jvi.00049-24

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