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Oriented immobilization of antibodies through peptide ligands for ultrasensitive detection of gastrin 17 in human serum via lateral flow immunoassay

Authors: Xintong Li , Jiale Cui , Jin Li , Yulian Wang , Guoqing Shi

Journal: Microchemical Journal

Doi: j.microc.2024.110819

Products & Services: Peptide Synthesis

Semi-rational design for enhancing thermostability of Culex pipiens acetylcholinesterase and sensitivity analysis of acephate

Authors: Shuoqi Jiang, Zhuangwei Zhang, Qiuya Gu, Xiaobin Yu

Journal: Sci Total Environ

PubMed ID: 38759926

Doi: 10.1016/j.scitotenv.2024.173282

Products & Services: Proteins, Expression, Isolation and Analysis

MiR-30a-5p isoform -1|1 promotes the progression of gastric cancer by inhibiting TMEM66 and reducing intratumoral cytotoxic T cells

Authors: Yanmiao Dai, Yudong Xu, Jie Shen, Caihong Hu, Xiaoli Li, Yongyu Chen, Yao Liu, Duanmin Hu

Journal: Exp Cell Res

PubMed ID: 38802035

Doi: 10.1016/j.yexcr.2024.114099

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Identification of a Fully Human Antibody VH Domain Targeting Anaplastic Lymphoma Kinase (ALK) with Applications in ALK-Positive Solid Tumor Immunotherapy

Authors: Chuan Chen, Zehua Sun, Zening Wang, Seungmin Shin, Abigail Berrios, John W Mellors, Dimiter S Dimitrov, Wei Li

Journal: Antibodies (Basel)

PubMed ID: 38804307

Doi: 10.3390/antib13020039

Products & Services: Proteins, Expression, Isolation and Analysis

Tardigrade secretory proteins protect biological structures from desiccation

Authors: Samuel Lim, Charles B Reilly, Zeina Barghouti, Benedetto Marelli, Jeffrey C Way, Pamela A Silver

Journal: Commun Biol

PubMed ID: 38796644

Doi: 10.1038/s42003-024-06336-w

Products & Services: Proteins, Expression, Isolation and Analysis

Kinetic Characterization and Identification of Key Active Site Residues of the L-Aspartate N-Hydroxylase, CreE

Authors: Sydney B Johnson, Hannah Valentino, Pablo Sobrado

Journal: Chembiochem

PubMed ID: 38775737

Doi: 10.1002/cbic.202400350

Products & Services: Molecular Biology Reagents

Structural Determinants of FeoB Nucleotide Promiscuity

Authors: Mark Lee, Kate Magante, Camilo Gómez-Garzón, Shelley M Payne, Aaron T Smith

Journal: biorxiv

PubMed ID: 38826458

Doi: 10.1101/2024.05.22.595361

Products & Services: Proteins, Expression, Isolation and Analysis

Distinct components of nucleoside-modified messenger RNA vaccines cooperate to instruct efficient germinal center responses

Authors: Emily Bettini, Aleksey Chudnovskiy, Giulia Protti, Sandra Nakadakari-Higa, Simona Ceglia, Diana Castaño, Joy Chiu, Hiromi Muramatsu, Thandiswa Mdluli, Edit Abraham, Zoltan Lipinszki, Ivan Maillard, Ying K Tam, Andrea Reboldi, Norbert Pardi, Roberto Spreafico, Gabriel D Victora, Michela Locci

Journal: biorxiv

PubMed ID: 38798523

Doi: 10.1101/2024.05.17.594726

Products & Services: Gene Synthesis

SUMOylated Golgin45 associates with PML-NB to transcriptionally regulate lipid metabolism genes during heat shock stress

Authors: Shuaiyang Jing, Jingkai Gao, Neeraj Tiwari, Yulei Du, Lianhui Zhu, Bopil Gim, Yi Qian, Xihua Yue, Intaek Lee

Journal: Commun Biol

PubMed ID: 38710927

Doi: 10.1038/s42003-024-06232-3

Products & Services: Proteins, Expression, Isolation and Analysis

Structural basis of substrate recognition and allosteric activation of the proapoptotic mitochondrial HtrA2 protease

Authors: Emelie E Aspholm, Jens Lidman, Björn M Burmann

Journal: Nat Commun

PubMed ID: 38816423

Doi: 10.1038/s41467-024-48997-5

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A new suite of reporter vectors and a novel landing site survey system to study cis-regulatory elements in diverse insect species

Authors: Kevin D Deem, Marc S Halfon, Yoshinori Tomoyasu

Journal: Sci Rep

PubMed ID: 38698030

Doi: 10.1038/s41598-024-60432-9

Products & Services: Gene Synthesis

Identification of an Immunodominant B-Cell Epitope in African Swine Fever Virus p30 Protein and Evidence of p30 Antibody-Mediated Antibody Dependent Cellular Cytotoxicity

Authors: Jessica C G Noll, Ruchi Rani, Salman L Butt, Maureen Hoch Vieira Fernandes, Gabriela Mansano do Nascimento, Mathias Martins, Leonardo C Caserta, Lina Covaleda, Diego G Diel

Journal: Viruses

PubMed ID: 38793639

Doi: 10.3390/v16050758

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Intranasal respiratory syncytial virus vaccine attenuated by codon-pair deoptimization of seven open reading frames is genetically stable and elicits mucosal and systemic immunity and protection against challenge virus replication in hamsters

Authors: Megan Levy, Jessica W Chen, Jaclyn A Kaiser, Hong-Su Park, Xueqiao Liu, Lijuan Yang, Celia Santos, Ursula J Buchholz, Cyril Le Nouën

Journal: PLoS Pathog

PubMed ID: 38739647

Doi: 10.1371/journal.ppat.1012198

Products & Services: Molecular Biology Reagents

Single dual-specific anti-PD-L1/TGF-β antibody synergizes with chemotherapy as neoadjuvant treatment for pancreatic ductal adenocarcinoma: a preclinical experimental study

Authors: Haoxiang Zhang, Jiaoshun Chen, Jianwei Bai, Jing Zhang, Shaoyi Huang, Liang Zeng, Pengfei Zhou, Qiang Shen, Tao Yin

Journal: Int J Surg

PubMed ID: 38489548

Doi: 10.1097/JS9.0000000000001226

Products & Services: Proteins, Expression, Isolation and Analysis

Divergent effects of olfactory receptors on transient receptor potential vanilloid 1 activation by capsaicin and eugenol

Authors: Sakura Moriyama, Yukie Takita, Shuji Hinuma, Shun'ichi Kuroda

Journal: Biosci Biotechnol Biochem

PubMed ID: 38734894

Doi: 10.1093/bbb/zbae060

Products & Services: Molecular Biology Reagents

HSD17B13 liquid-liquid phase separation promotes leukocyte adhesion in chronic liver inflammation

Authors: Jing Ye, Xiyu Huang, Manman Yuan, Jinglin Wang, Ru Jia, Tianyi Wang, Yang Tan, Shun Zhu, Qiang Xu, Xingxin Wu

Journal: J Mol Cell Biol

PubMed ID: 38692847

Doi: 10.1093/jmcb/mjae018

Products & Services: Molecular Biology Reagents

Staphylococcal peroxidase inhibitor (SPIN): Residue-level investigation of the helical bundle domain

Authors: Soheila Fatehi, Timothy J Herdendorf, Nicoleta T Ploscariu, Brian V Geisbrecht

Journal: Arch Biochem Biophys

PubMed ID: 38705227

Doi: 10.1016/j.abb.2024.110023

Products & Services: Molecular Biology Reagents

Establishment of an ELISA Based on a Recombinant Antigenic Protein Containing Multiple Prominent Epitopes for Detection of African Swine Fever Virus Antibodies

Authors: Dossêh Jean Apôtre Afayibo, Zhonghui Zhang, Hualin Sun, Jingsheng Fu, Yaru Zhao, Tharheer Oluwashola Amuda, Mengli Wu, Junzheng Du, Guiquan Guan, Qingli Niu, Jifei Yang, Hong Yin

Journal: Microorganisms

PubMed ID: 38792774

Doi: 10.3390/microorganisms12050943

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A novel mouse model for investigating α-synuclein aggregates in oligodendrocytes: implications for the glial cytoplasmic inclusions in multiple system atrophy

Authors: Tomoyuki Ishimoto, Miki Oono, Seiji Kaji, Takashi Ayaki, Katsuya Nishida, Itaru Funakawa, Takakuni Maki, Shu-Ichi Matsuzawa, Ryosuke Takahashi, Hodaka Yamakado

Journal: Mol Brain

PubMed ID: 38790036

Doi: 10.1186/s13041-024-01104-7

Products & Services: Molecular Biology Reagents

Ser/Leu-swapped cell-free translation system constructed with natural/in vitro transcribed-hybrid tRNA set

Authors: Tomoshige Fujino, Ryogo Sonoda, Taito Higashinagata, Emi Mishiro-Sato, Keiko Kano, Hiroshi Murakami

Journal: Nat Commun

PubMed ID: 38755134

Doi: 10.1038/s41467-024-48056-z

Products & Services: Peptide Synthesis

Saccharomyces cerevisiae oral immunization in mice using multi-antigen of the African swine fever virus elicits a robust immune response

Authors: Shuo Gao, Wenfeng Zuo, Chao Kang, Zhong Zou, Kaiqi Zhang, Jun Qiu, Xiaomin Shang, Jingjing Li, Yuanfeng Zhang, Qi Zuo, Ya Zhao, Meilin Jin

Journal: Front Immunol

PubMed ID: 38742108

Doi: 10.3389/fimmu.2024.1373656

Products & Services: Gene Synthesis

One substrate many enzymes virtual screening uncovers missing genes of carnitine biosynthesis in human and mouse

Authors: Marco Malatesta, Emanuele Fornasier, Martino Luigi Di Salvo, Angela Tramonti, Erika Zangelmi, Alessio Peracchi, Andrea Secchi, Eugenia Polverini, Gabriele Giachin, Roberto Battistutta, Roberto Contestabile, Riccardo Percudani

Journal: Nat Commun

PubMed ID: 38615009

Doi: 10.1038/s41467-024-47466-3

Products & Services: Molecular Biology Reagents

Programmable RNA 5-methylcytosine (m5C) modification of cellular RNAs by dCasRx conjugated methyltransferase and demethylase

Authors: Tao Zhang, Feiyu Zhao, Jinze Li, Xiaodi Sun, Xiyun Zhang, Hejun Wang, Peng Fan, Liangxue Lai, Zhanjun Li, Tingting Sui

Journal: Nucleic Acids Res

PubMed ID: 38366553

Doi: 10.1093/nar/gkae110

Products & Services: Molecular Biology Reagents

The impact of HBx protein on mitochondrial dynamics and associated signaling pathways strongly depends on the hepatitis B virus genotype

Authors: Anja Schollmeier, Michael Basic, Mirco Glitscher, Eberhard Hildt

Journal: J Virol

PubMed ID: 38629837

Doi: 10.1128/jvi.00424-24

Products & Services: Molecular Biology Reagents

Efficacy of genotype-matched vaccine against re-emerging genotype V Japanese encephalitis virus

Authors: Jae-Deog Kim, Ah-Ra Lee, Dah-Hyun Moon, Young-Uk Chung, Su-Yeon Hong, Hyo Je Cho, Tae Hyun Kang, Yo Han Jang, Myung Hyun Sohn, Baik-Lin Seong, Sang-Uk Seo

Journal: Emerg Microbes Infect

PubMed ID: 38618740

Doi: 10.1080/22221751.2024.2343910

Products & Services: Proteins, Expression, Isolation and Analysis

Efficient activity screening of new glucuronoyl esterases using a pNP-based assay

Authors: Michael S Madsen, Pedro A Martins, Jane W Agger

Journal: Enzyme Microb Technol

PubMed ID: 38581869

Doi: 10.1016/j.enzmictec.2024.110444

Products & Services: Molecular Biology Reagents

Food-Grade Expression of Two Laccases in and Study on Their Enzymatic Degradation Characteristics for Mycotoxins

Authors: Zhen Sun, Yingxin You, Huidong Xu, Yang You, Wenjing He, Zhouping Wang, Aitao Li, Yu Xia

Journal: J Agric Food Chem

PubMed ID: 38600054

Doi: 10.1021/acs.jafc.4c00521

Products & Services: Gene Synthesis

Remotely controlled drug release in deep brain regions of non-human primates

Authors: Matthew G Wilson, Taylor D Webb, Henrik Odéen, Jan Kubanek

Journal: J Control Release

PubMed ID: 38604386

Doi: 10.1016/j.jconrel.2024.04.013

Products & Services: Proteins, Expression, Isolation and Analysis

An Elastin-Derived Composite Matrix for Enhanced Vascularized and Innervated Bone Tissue Reconstruction: From Material Development to Preclinical Evaluation

Authors: Nadia Mahmoudi, Micaela Roque, Bruno Paiva Dos Santos, Hugo Oliveira, Robin Siadous, Sylvie Rey, Elisabeth Garanger, Sébastien Lecommandoux, Sylvain Catros, Bertrand Garbay, Joëlle Amédée Vilamitjana

Journal: Adv Healthc Mater

PubMed ID: 38651610

Doi: 10.1002/adhm.202303765

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Broad-spectrum Delta-BA2 tandem-fused heterodimer mRNA vaccine delivered by lipopolyplex

Authors: Pei Du, Lei Huang, Yi Fang, Fanfan Zhao, Qianyun Li, Xuehui Ma, Ruiqi Li, Qian Chen, Haifa Shen, Qihui Wang, Hangwen Li, George Fu Gao

Journal: PLoS Pathog

PubMed ID: 38557908

Doi: 10.1371/journal.ppat.1012116

Products & Services: Molecular Biology Reagents

Durlobactam, a Diazabicyclooctane β-Lactamase Inhibitor, Inhibits BlaC and Peptidoglycan Transpeptidases of

Authors: Mary Nantongo, David C Nguyen, Christopher R Bethel, Magdalena A Taracila, Qing Li, Khalid M Dousa, Eunjeong Shin, Sebastian G Kurz, Liem Nguyen, Barry N Kreiswirth, W Henry Boom, Mark S Plummer, Robert A Bonomo

Journal: ACS Infect Dis

PubMed ID: 38619138

Doi: 10.1021/acsinfecdis.4c00119

Products & Services: Molecular Biology Reagents

Mechanistic insights into the alternative ribosome recycling by HflXr

Authors: Savannah M Seely, Ritwika S Basu, Matthieu G Gagnon

Journal: Nucleic Acids Res

PubMed ID: 38407413

Doi: 10.1093/nar/gkae128

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Receptor-recognition and antiviral mechanisms of retrovirus-derived human proteins

Authors: Shashank Khare, Miryam I Villalba, Juan C Canul-Tec, Arantza Balsebre Cajiao, Anand Kumar, Marija Backovic, Felix A Rey, Els Pardon, Jan Steyaert, Camilo Perez, Nicolas Reyes

Journal: Nat Struct Mol Biol

PubMed ID: 38671230

Doi: 10.1038/s41594-024-01295-6

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CDK5-mediated rearrangement of vimentin during Duck Tembusu virus infection inhibits viral replication

Authors: Guangbin Bao, Shinuo Fan, Chunyan Hu, Chen Li, Fei Ma, Guijun Wang, Hongjie Fan, Qing Wang

Journal: Vet Microbiol

PubMed ID: 38574695

Doi: 10.1016/j.vetmic.2024.110071

Products & Services: Proteins, Expression, Isolation and Analysis

The Trimeric Autotransporter Adhesin SadA from spp as a Novel Bacterial Surface Display System

Authors: Shuli Sang, Wenge Song, Lu Lu, Qikun Ou, Yiyan Guan, Haoxia Tao, Yanchun Wang, Chunjie Liu

Journal: Vaccines (Basel)

PubMed ID: 38675781

Doi: 10.3390/vaccines12040399

Products & Services: Proteins, Expression, Isolation and Analysis

Plasmodium RNA triphosphatase validation as antimalarial target

Authors: Sonia Moliner-Cubel, Noemi Bahamontes-Rosa, Ane Rodriguez-Alejandre, Pamela M Nassau, Argyrides Argyrou, Anshu Bhardwaja, Rachel C Buxton, David Calvo-Vicente, Bernadette Mouzon, William McDowell, Alfonso Mendoza-Losana, Maria G Gomez-Lorenzo

Journal: Int J Parasitol Drugs Drug Resist

PubMed ID: 38810336

Doi: 10.1016/j.ijpddr.2024.100537

Products & Services: Molecular Biology Reagents

Knockdown of heat shock protein family D member 1 (HSPD1) in lung cancer cell altered secretome profile and cancer-associated fibroblast induction

Authors: Siripat Aluksanasuwan, Keerakarn Somsuan, Jatuporn Ngoenkam, Wararat Chiangjong, Artitaya Rongjumnong, Atthapan Morchang, Somchai Chutipongtanate, Sutatip Pongcharoen

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 38663552

Doi: 10.1016/j.bbamcr.2024.119736

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Two mosquito salivary antigens demonstrate promise as biomarkers of recent exposure to infected mosquito bites

Authors: Sarah Lapidus, Morgan M Goheen, Mouhamad Sy, Awa B Deme, Ibrahima Mbaye Ndiaye, Younous Diedhiou, Amadou Moctar Mbaye, Kelly A Hagadorn, Seynabou Diouf Sene, Mariama Nicole Pouye, Laty Gaye Thiam, Aboubacar Ba, Noemi Guerra, Alassane Mbengue, Hamidah Raduwan, Inés Vigan-Womas, Sunil Parikh, Albert I Ko, Daouda Ndiaye, Erol Fikrig, Yu-Min Chuang, Amy K Bei

Journal: medrxiv

PubMed ID: 38712295

Doi: 10.1101/2024.04.20.24305430

Products & Services: Proteins, Expression, Isolation and Analysis

Specificity of DNA ADP-Ribosylation Reversal by NADARs

Authors: Bara Cihlova, Yang Lu, Andreja Mikoč, Marion Schuller, Ivan Ahel

Journal: Toxins (Basel)

PubMed ID: 38787060

Doi: 10.3390/toxins16050208

Products & Services: Molecular Biology Reagents

Development of an isotope dilution mass spectrometry assay for the quantification of insulin based on signature peptide analysis

Authors: Shangying Ma, Rimei He, Tingting Jiang, Zhishang Hu, Zihong Ye, Wei Mi

Journal: Anal Bioanal Chem

PubMed ID: 38556594

Doi: 10.1007/s00216-024-05258-0

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Blue light induced ferroptosis via STAT3/GPX4/SLC7A11/FTH1 in conjunctiva epithelium in vivo and in vitro

Authors: Qianjie Yang, Yutong Xia, Kuangqi Chen, Yinhao Wang, Dongjie Song, Jiru Zhu, Jianping Tong, Ye Shen

Journal: J Photochem Photobiol B

PubMed ID: 38663336

Doi: 10.1016/j.jphotobiol.2024.112908

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iJAZ-based approach to engineer lepidopteran pest resistance in multiple crop species

Authors: Huijuan Mo, Huimin Chang, Ge Zhao, Guanjing Hu, Xiumei Luo, Xue Jia, Zhenlu Xu, Guangming Ren, Li Feng, Jonathan F Wendel, Xiaoya Chen, Maozhi Ren, Fuguang Li

Journal: Nat Plants

PubMed ID: 38684916

Doi: 10.1038/s41477-024-01682-3

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Specifically targeting antimicrobial peptides for inhibition of Candidatus Liberibacter asiaticus

Authors: Samavath Mallawarachchi, Haoqi Wang, Nirmitee Mulgaonkar, Sonia Irigoyen, Carmen Padilla, Kranthi Mandadi, James Borneman, Sandun Fernando

Journal: J Appl Microbiol

PubMed ID: 38509024

Doi: 10.1093/jambio/lxae061

Products & Services: Proteins, Expression, Isolation and Analysis

The transcription factor BMI1 increases hypoxic signaling in oral cavity epithelia

Authors: Jorge Baquero, Xiao-Han Tang, Annalisa Ferrotta, Tuo Zhang, Krysta M DiKun, Lorraine J Gudas

Journal: Biochim Biophys Acta Mol Basis Dis

PubMed ID: 38599260

Doi: 10.1016/j.bbadis.2024.167161

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LLPS of FXR proteins drives replication organelle clustering for β-coronaviral proliferation

Authors: Meng Li, Yali Hou, Yuzheng Zhou, Zhenni Yang, Hongyu Zhao, Tao Jian, Qianxi Yu, Fuxing Zeng, Xiaotian Liu, Zheng Zhang, Yan G Zhao

Journal: J Cell Biol

PubMed ID: 38587486

Doi: 10.1083/jcb.202309140

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Combined sensory, volatilome and transcriptome analyses identify a limonene terpene synthase as a major contributor to the characteristic aroma of a Coffea arabica L specialty coffee

Authors: Lison Marie, Jean-Christophe Breitler, Pingdwende Kader Aziz Bamogo, Mélanie Bordeaux, Séverine Lacombe, Maëlle Rios, Marc Lebrun, Renaud Boulanger, Eveline Lefort, Sunao Nakamura, Yudai Motoyoshi, Delphine Mieulet, Claudine Campa, Laurent Legendre, Benoît Bertrand

Journal: BMC Plant Biol

PubMed ID: 38566027

Doi: 10.1186/s12870-024-04890-3

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The gene "degrees of kevin bacon" (dokb) regulates a social network behaviour in Drosophila melanogaster

Authors: Rebecca Rooke, Joshua J Krupp, Amara Rasool, Mireille Golemiec, Megan Stewart, Jonathan Schneider, Joel D Levine

Journal: Nat Commun

PubMed ID: 38688961

Doi: 10.1038/s41467-024-47499-8

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Development of nanobodies targeting hepatocellular carcinoma and application of nanobody-based CAR-T technology

Authors: Keming Lin, Baijin Xia, Xuemei Wang, Xin He, Mo Zhou, Yingtong Lin, Yidan Qiao, Rong Li, Qier Chen, Yuzhuang Li, Jinzhu Feng, Tao Chen, Cancan Chen, Xinyu Li, Hui Zhang, Lijuan Lu, Bingfeng Liu, Xu Zhang

Journal: J Transl Med

PubMed ID: 38610029

Doi: 10.1186/s12967-024-05159-x

Products & Services: Proteins, Expression, Isolation and Analysis

Visualization of the Association of Dimeric Protein Complexes on Specific Enhancers in the Salivary Gland Nuclei of Larva

Authors: Solène Vanderperre, Samir Merabet

Journal: Cells

PubMed ID: 38607052

Doi: 10.3390/cells13070613

Products & Services: Gene Synthesis

Systemic Effects of a Phage Cocktail on Healthy Weaned Piglets

Authors: Yankun Liu, Yan Lin, Weiyun Zhu

Journal: Biology (Basel)

PubMed ID: 38666883

Doi: 10.3390/biology13040271

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