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页码: 163/1026 每页显示数量
Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients
Authors: Xiuyuan Lu, Yuki Hosono, Masamichi Nagae, Shigenari Ishizuka, Eri Ishikawa, Daisuke Motooka, Yuki Ozaki, Nicolas Sax, Yuichi Maeda, Yasuhiro Kato, Takayoshi Morita, Ryo Shinnakasu, Takeshi Inoue, Taishi Onodera, Takayuki Matsumura, Masaharu Shinkai, Takashi Sato, Shota Nakamura, Shunsuke Mori, Teru Kanda, Emi E Nakayama, Tatsuo Shioda, Tomohiro Kurosaki, Kiyoshi Takeda, Atsushi Kumanogoh, Hisashi Arase, Hironori Nakagami, Kazuo Yamashita, Yoshimasa Takahashi, Sho Yamasaki
Journal: J Exp Med
PubMed ID: 34647971
Doi: 10.1084/jem.20211327
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Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle
Authors: Harriet P Lo, Ye-Wheen Lim, Zherui Xiong, Nick Martel, Charles Ferguson, Nicholas Ariotti, Jean Giacomotto, James Rae, Matthias Floetenmeyer, Shayli Varasteh Moradi, Ya Gao, Vikas A Tillu, Di Xia, Huang Wang, Samira Rahnama, Susan J Nixon, Michele Bastiani, Ryan D Day, Kelly A Smith, Nathan J Palpant, Wayne A Johnston, Kirill Alexandrov, Brett M Collins, Thomas E Hall, Robert G Parton
Journal: J Cell Biol
PubMed ID: 34633413
Doi: 10.1083/jcb.201905065
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Profiling sirtuin activity using Copper-free click chemistry
Authors: Alyson M Curry, Ian Cohen, Song Zheng, Jessica Wohlfahrt, Dawanna S White, Dickson Donu, Yana Cen
Journal: Bioorg Chem
PubMed ID: 34655842
Doi: 10.1016/j.bioorg.2021.105413
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T cells promote metastasis by regulating extracellular matrix remodeling following chemotherapy
Authors: Jozafina Haj-Shomaly, Avital Vorontsova, Tamar Barenholz-Cohen, Oshrat Levi-Galibov, Mahesh Devarasetty, Michael Timaner, Ziv Raviv, Tim J Cooper, Shay Soker, Peleg Hasson, Daphne Weihs, Ruth Scherz-Shouval, Yuval Shaked
Journal: Cancer Res
PubMed ID: 34666995
Doi: 10.1158/0008-5472.CAN-21-1012
Products & Services: Catalog Antibody   
Label-Free Colorimetric Method for Detection of by Trimming the G-Quadruplex DNAzyme with CRISPR/Cas12a
Authors: Xueyun Chen, Liu Wang, Fang He, Ganghui Chen, Linlin Bai, Kaiyu He, Fang Zhang, Xiahong Xu
Journal: Anal Chem
PubMed ID: 34645259
Doi: 10.1021/acs.analchem.1c03468
Products & Services: Bacterial Expression   
Exosome-mediated delivery of inflammation-responsive mRNA for controlled atherosclerosis treatment
Authors: Te Bu, Zhelong Li, Ying Hou, Wenqi Sun, Rongxin Zhang, Lianbi Zhao, Mengying Wei, Guodong Yang, Lijun Yuan
Journal: Theranostics
PubMed ID: 34815799
Doi: 10.7150/thno.64229
Products & Services: Gene Synthesis   
21-Hydroxylase-Specific CD8+ T Cells in Autoimmune Addison's Disease Are Restricted by HLA-A2 and HLA-C7 Molecules
Authors: Alexander Hellesen, Sigrid Aslaksen, Lars Breivik, Ellen Christine Røyrvik, Øyvind Bruserud, Kine Edvardsen, Karl Albert Brokstad, Anette Susanne Bøe Wolff, Eystein Sverre Husebye, Eirik Bratland
Journal: Front Immunol
PubMed ID: 34721410
Doi: 10.3389/fimmu.2021.742848
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A comparative study of mesenchymal stem cells cultured as cell-only aggregates and in encapsulated hydrogels
Authors: Fiona R Passanha, David B Gomes, Justyna Piotrowska, Lorenzo Moroni, Matthew B Baker, Vanessa L S LaPointe
Journal: J Tissue Eng Regen Med
PubMed ID: 34655456
Doi: 10.1002/term.3257
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Molecular Basis of a Dominant SARS-CoV-2 Spike-Derived Epitope Presented by HLA-A*02:01 Recognised by a Public TCR
Authors: Christopher Szeto, Andrea T Nguyen, Christian A Lobos, Demetra S M Chatzileontiadou, Dhilshan Jayasinghe, Emma J Grant, Alan Riboldi-Tunnicliffe, Corey Smith, Stephanie Gras
Journal: Cells
PubMed ID: 34685626
Doi: 10.3390/cells10102646
Products & Services: Stable Cell Lines   
Evaluation of the correlation between the access SARS-CoV-2 IgM and IgG II antibody tests with the SARS-CoV-2 surrogate virus neutralization test
Authors: Yutaro Kitagawa, Kazuo Imai, Masaru Matsuoka, Ai Fukada, Katsumi Kubota, Momoko Sato, Tomohito Takada, Sakiko Noguchi, Norihito Tarumoto, Shigefumi Maesaki, Shinichi Takeuchi, Takuya Maeda
Journal: J Med Virol
PubMed ID: 34524695
Doi: 10.1002/jmv.27338
Products & Services: Serology SARS-Cov-2 detection kits   
AuNPs- Aβ-Ni-HRP sandwich assay: A new sensitive colorimetric method for the detection of Aβ
Authors: Zeeshan A Khan, Seungkyung Park
Journal: Talanta
PubMed ID: 34736673
Doi: 10.1016/j.talanta.2021.122946
Products & Services: Recombinant Proteins   
TREM1 Regulates Neuroinflammatory Injury by Modulate Proinflammatory Subtype Transition of Microglia and Formation of Neutrophil Extracellular Traps Interaction With SYK in Experimental Subarachnoid Hemorrhage
Authors: Xinyan Wu, Hanhai Zeng, Chaoran Xu, Huaijun Chen, Linfeng Fan, Hang Zhou, Qian Yu, Xiongjie Fu, Yucong Peng, Feng Yan, Xiaobo Yu, Gao Chen
Journal: Front Immunol
PubMed ID: 34721438
Doi: 10.3389/fimmu.2021.766178
Products & Services: Recombinant Antibody Expression   
Effective killing of cells expressing CD276 (B7-H3) by a bispecific T cell engager based on a new fully human antibody
Authors: Xianglei Liu, Doncho Zhelev, Cynthia Adams, Chuan Chen, John W Mellors, Dimiter S Dimitrov
Journal: Transl Oncol
PubMed ID: 34601396
Doi: 10.1016/j.tranon.2021.101232
Xeno-Nucleic Acid (XNA) 2'-Fluoro-Arabino Nucleic Acid (FANA) Aptamers to the Receptor-Binding Domain of SARS-CoV-2 S Protein Block ACE2 Binding
Authors: Irani Alves Ferreira-Bravo, Jeffrey J DeStefano
Journal: Viruses
PubMed ID: 34696413
Doi: 10.3390/v13101983
Low-Field NMR Analysis of Chicken Patties Prepared with Woody Breast Meat and Implications to Meat Quality
Authors: Xiao Sun, Jinjie You, Yan Dong, Ligen Xu, Clay J Maynard, Casey M Owens
Journal: Foods
PubMed ID: 34681548
Doi: 10.3390/foods10102499
Tomatidine and Patchouli Alcohol as Inhibitors of SARS-CoV-2 Enzymes (3CLpro, PLpro and NSP15) by Molecular Docking and Molecular Dynamics Simulations
Authors: Rafat Zrieq, Iqrar Ahmad, Mejdi Snoussi, Emira Noumi, Marcello Iriti, Fahad D Algahtani, Harun Patel, Mohd Saeed, Munazzah Tasleem, Shadi Sulaiman, Kaïss Aouadi, Adel Kadri
Journal: Int J Mol Sci
PubMed ID: 34639036
Doi: 10.3390/ijms221910693
PP2A/B55α substrate recruitment as defined by the retinoblastoma-related protein p107
Authors: Holly Fowle, Ziran Zhao, Qifang Xu, Jason S Wasserman, Xinru Wang, Mary Adeyemi, Felicity Feiser, Alison N Kurimchak, Diba Atar, Brennan C McEwan, Arminja N Kettenbach, Rebecca Page, Wolfgang Peti, Roland L Dunbrack, Xavier Graña
Journal: Elife
PubMed ID: 34661528
Doi: 10.7554/eLife.63181
miR825-5p targets the TIR-NBS-LRR gene MIST1 and down-regulates basal immunity against Pseudomonas syringae in Arabidopsis
Authors: Diego López-Márquez, Ángel Del-Espino, Nieves López-Pagán, Edgar A Rodríguez-Negrete, Ignacio Rubio-Somoza, Javier Ruiz-Albert, Eduardo R Bejarano, Carmen R Beuzón
Journal: J Exp Bot
PubMed ID: 34329403
Doi: 10.1093/jxb/erab354
Androgen receptor phosphorylated at Ser815: The expression and function in the prostate and tumor-derived cells
Authors: Kosuke Yokobori, Yuki Kawasaki, Yoshitaka Sekine, Sumihito Nobusawa, Toshiyuki Sakaki, Masahiko Negishi, Satoru Kakizaki
Journal: Biochem Pharmacol
PubMed ID: 34715066
Doi: 10.1016/j.bcp.2021.114794
Products & Services: Plasmid DNA Preparation   
Molecular Characteristics of Repotrectinib That Enable Potent Inhibition of TRK Fusion Proteins and Resistant Mutations
Authors: Brion W Murray, Evan Rogers, Dayong Zhai, Wei Deng, Xi Chen, Paul A Sprengeler, Xin Zhang, Armin Graber, Siegfried H Reich, Shanna Stopatschinskaja, Benjamin Solomon, Benjamin Besse, Alexander Drilon
Journal: Mol Cancer Ther
PubMed ID: 34625502
Doi: 10.1158/1535-7163.MCT-21-0632
Products & Services: Plasmid DNA Preparation   
MicroRNA‑200c‑3p suppresses intervertebral disc degeneration by targeting RAP2C/ERK signaling
Authors: Jianping Cao, Meng Jiang, Huafeng Ren, Kai Xu
Journal: Mol Med Rep
PubMed ID: 34676879
Doi: 10.3892/mmr.2021.12505
Products & Services: Plasmid DNA Preparation   
KDM5B protein expressed in viable and fertile ΔARID mice exhibit no demethylase activity
Authors: Shirin Jamshidi, Steven Catchpole, Jie Chen, Chi Wai Eric So, Joy Burchell, Khondaker Miraz Rahman, Joyce Taylor-Papadimitriou
Journal: Int J Oncol
PubMed ID: 34713299
Doi: 10.3892/ijo.2021.5276
Products & Services: Plasmid DNA Preparation   
Lamin A/C recruits ssDNA protective proteins RPA and RAD51 to stalled replication forks to maintain fork stability
Authors: Simona Graziano, Nuria Coll-Bonfill, Barbara Teodoro-Castro, Sahiti Kuppa, Jessica Jackson, Elena Shashkova, Urvashi Mahajan, Alessandro Vindigni, Edwin Antony, Susana Gonzalo
Journal: J Biol Chem
PubMed ID: 34648766
Doi: 10.1016/j.jbc.2021.101301
Products & Services: Plasmid DNA Preparation   
Influence of Primary Structure on Fragmentation of Native-Like Proteins by Ultraviolet Photodissociation
Authors: Luis A Macias, Sarah N Sipe, Inês C Santos, Aarti Bashyal, M Rachel Mehaffey, Jennifer S Brodbelt
Journal: J Am Soc Mass Spectrom
PubMed ID: 34714071
Doi: 10.1021/jasms.1c00269
Products & Services: Peptide Synthesis   
Engineering Extracellular Vesicles Enriched with Palmitoylated ACE2 as COVID-19 Therapy
Authors: Feng Xie, Peng Su, Ting Pan, Xiaoxue Zhou, Heyu Li, Huizhe Huang, Aijun Wang, Fangwei Wang, Jun Huang, Haiyan Yan, Linghui Zeng, Long Zhang, Fangfang Zhou
Journal: Adv Mater
PubMed ID: 34665481
Doi: 10.1002/adma.202103471
Products & Services: Serology SARS-Cov-2 detection kits   
A BioBricks toolbox for metabolic engineering of the tetracenomycin pathway
Authors: Jennifer T Nguyen, Kennedy K Riebschleger, Katelyn V Brown, Nina M Gorgijevska, S Eric Nybo
Journal: Biotechnol J.
PubMed ID: 34719127
Doi: doi.org/10.1002/biot.202100371
Products & Services: Gene Synthesis   
Cross talk between the upstream exon-intron junction and Prp2 facilitates splicing of non-consensus introns
Authors: Stefan Hümmer, Sonia Borao, Angel Guerra-Moreno, Luca Cozzuto, Elena Hidalgo, José Ayté
Journal: Cell Rep
PubMed ID: 34706246
Doi: 10.1016/j.celrep.2021.109893
Products & Services: PCR Cloning and Subcloning   
The expression, localisation and interactome of pigeon CRY2
Authors: Spencer D Balay, Tobias Hochstoeger, Alexandra Vilceanu, E Pascal Malkemper, William Snider, Gerhard Dürnberger, Karl Mechtler, Stefan Schuechner, Egon Ogris, Gregory C Nordmann, Lyubov Ushakova, Simon Nimpf, David A Keays
Journal: Sci Rep
PubMed ID: 34645873
Doi: 10.1038/s41598-021-99207-x
Products & Services: PCR Cloning and Subcloning   
Newcastle Disease Virus Vectored Chicken Infectious Anaemia Vaccine Induces Robust Immune Response in Chickens
Authors: Madhan Mohan Chellappa, Sohini Dey, Dinesh Chandra Pathak, Asmita Singh, Narayan Ramamurthy, Saravanan Ramakrishnan, Asok Kumar Mariappan, Kuldeep Dhama, Vikram N Vakharia
Journal: Viruses
PubMed ID: 34696415
Doi: 10.3390/v13101985
Products & Services: ORF cDNA Clones/MolecularCloud   
Anti-platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein
Authors: Andreas Greinacher, Kathleen Selleng, Julia Mayerle, Raghavendra Palankar, Jan Wesche, Sven Reiche, Andrea Aebischer, Theodore E Warkentin, Maximilian Muenchhoff, Johannes C Hellmuth, Oliver T Keppler, Daniel Duerschmied, Achim Lother, Siegbert Rieg, Meinrad Paul Gawaz, Karin Anne Lydia Mueller, Christian S Scheer, Matthias Napp, Klaus Hahnenkamp, Guglielmo Lucchese, Antje Vogelgesang, Agnes Flöel, Piero Lovreglio, Angela Stufano, Rolf Marschalek, Thomas Thiele
Journal: Blood
PubMed ID: 34280256
Doi: 10.1182/blood.2021012938
Products & Services: Mutant Libraries   
The Sigma-1 receptor is an ER-localized type II membrane protein
Authors: Neeraj Sharma, Chaitanya Patel, Marina Shenkman, Amit Kessel, Nir Ben-Tal, Gerardo Z Lederkremer
Journal: J Biol Chem
PubMed ID: 34648767
Doi: 10.1016/j.jbc.2021.101299
Products & Services: Monoclonal Antibody Services   
Novel Binding Partners for CCT and PhLP1 Suggest a Common Folding Mechanism for WD40 Proteins with a 7-Bladed Beta-Propeller Structure
Authors: Wai Shun Mak, Tsz Ming Tsang, Tsz Yin Chan, Georgi L Lukov
Journal: Proteomes
PubMed ID: 34698247
Doi: 10.3390/proteomes9040040
Products & Services: DNA Sequencing   
A heparan-sulfate-bearing syndecan-1 glycoform is a distinct surface marker for intra-tumoral myeloid-derived suppressor cells
Authors: Thomas Welte, Junhua Mai, Zhe Zhang, Shaohui Tian, Guodong Zhang, Yitian Xu, Licheng Zhang, Shu-Shia Chen, Tian Wang, Haifa Shen
Journal: iScience
PubMed ID: 34825135
Doi: 10.1016/j.isci.2021.103349
Products & Services: DNA Sequencing   
Cytotoxin antibody-based colourimetric sensor for field-level differential detection of elapid among big four snake venom
Authors: Sherin Kaul, L Sai Keerthana, Pankaj Kumar, Komal Birader, Yathirajarao Tammineni, Deepali Rawat, Pankaj Suman
Journal: PLoS Negl Trop Dis
PubMed ID: 34634067
Doi: 10.1371/journal.pntd.0009841
Products & Services: DNA Sequencing   
The periplasmic expression and purification of AA15 lytic polysaccharide monooxygenases from insect species in Escherichia coli
Authors: João Paulo L Franco Cairo, Dnane V Almeida, André Damasio, Wanius Garcia, Fabio M Squina
Journal: Protein Expr Purif
PubMed ID: 34655732
Doi: 10.1016/j.pep.2021.105994
Products & Services: Custom Vector Construction   
Characterization and Inhibition of 1-Deoxy-d-Xylulose 5-Phosphate Reductoisomerase: A Promising Drug Target in and
Authors: Haley S Ball, Misgina B Girma, Mosufa Zainab, Iswarduth Soojhawon, Robin D Couch, Schroeder M Noble
Journal: ACS Infect Dis
PubMed ID: 34672535
Doi: 10.1021/acsinfecdis.1c00132
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Bacterial Quorum-Quenching Lactonase Hydrolyzes Fungal Mycotoxin and Reduces Pathogenicity of -Suggesting a Mechanism of Bacterial Antagonism
Authors: Shlomit Dor, Dov Prusky, Livnat Afriat-Jurnou
Journal: J Fungi (Basel)
PubMed ID: 34682247
Doi: 10.3390/jof7100826
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Strongly Hydrogen-Bonded Schiff Base and Adjoining Polyene Twisting in the Retinal Chromophore of Schizorhodopsins
Authors: Tomomi Shionoya, Manish Singh, Misao Mizuno, Hideki Kandori, Yasuhisa Mizutani
Journal: Biochemistry
PubMed ID: 34601881
Doi: 10.1021/acs.biochem.1c00529
Products & Services: Codon Optimization   
A Thermostable Cas12b from Leverages One-pot Detection of SARS-CoV-2 Variants of Concern
Authors: Long T Nguyen, Nicolas C Macaluso, Brianna L M Pizzano, Melanie N Cash, Jan Spacek, Jan Karasek, Rhoel R Dinglasan, Marco Salemi, Piyush K Jain
Journal: medrxiv
PubMed ID: 34704101
Doi: 10.1101/2021.10.15.21265066
Products & Services: Codon Optimization   
Homocysteine Inhibits Pro-Insulin Receptor Cleavage and Causes Insulin Resistance Via Protein Cysteine-Homocysteinylation
Authors: Xuan Zhang, Yuan-Yuan Qu, Lian Liu, Ya-Nan Qiao, Hao-Ran Geng, Yan Lin, Wei Xu, Jing Cao, Jian-Yuan Zhao
Journal: Cell Rep
PubMed ID: 34644569
Doi: 10.2139/ssrn.3830772
Identification and Characterization of a Novel Epitope of ASFV-Encoded dUTPase by Monoclonal Antibodies
Authors: Shuai Zhang, Rui Wang, Xiaojing Zhu, Jiaxin Jin, Wenlong Lu, Xuyang Zhao, Bo Wan, Yifei Liao, Qin Zhao, Christopher L Netherton, Guoqing Zhuang, Aijun Sun, Gaiping Zhang
Journal: Viruses
PubMed ID: 34834981
Doi: 10.3390/v13112175
Products & Services: Peptide Synthesis   
Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues
Authors: Sanket S Ponia, Shelly J Robertson, Kristin L McNally, Gayatri Subramanian, Gail L Sturdevant, Matthew Lewis, Forrest Jessop, Catherine Kendall, Dylan Gallegos, Arielle Hay, Cindi Schwartz, Rebecca Rosenke, Greg Saturday, Catherine M Bosio, Craig Martens, Sonja M Best
Journal: Cell Rep
PubMed ID: 34706234
Doi: 10.1016/j.celrep.2021.109888
Products & Services: Mammalian Expression   
Waning humoral response 6 months after SARS-CoV-2 vaccination with the mRNA-BNT162b2 vaccine in hemodialysis patients: time for a boost
Authors: Tamara Davidovic, Judith Schimpf, Armin Abbassi-Nik, Richard Stockinger, Hannelore Sprenger-Mähr, Karl Lhotta, Emanuel Zitt
Journal: Kidney Int
PubMed ID: 34656642
Doi: 10.1016/j.kint.2021.10.006
Black Phosphorus Nanoparticles Promote Osteogenic Differentiation of EMSCs Through Upregulated TG2 Expression
Authors: Naiyan Lu, Xinhe Wang, Wentao Shi, Lu Bian, Xuan Zhang, Guofeng Yang, Xue Tang, Jun Wang, Yin Zou, Yuyan Weng
Journal: Nanoscale Res Lett
PubMed ID: 34637014
Doi: 10.1186/s11671-021-03610-2
Products & Services: Custom Vector Construction   
In vivo Profiling of the Alk Proximitome in the Developing Drosophila Brain
Authors: Ezgi Uçkun, Georg Wolfstetter, Vimala Anthonydhason, Sanjay Kumar Sukumar, Ganesh Umapathy, Linnea Molander, Johannes Fuchs, Ruth H Palmer
Journal: J Mol Biol
PubMed ID: 34624297
Doi: 10.1016/j.jmb.2021.167282
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Quantifying oxidation of cellulose-associated glucuronoxylan by two lytic polysaccharide monooxygenases from
Authors: Olav A Hegnar, Heidi Østby, Dejan M Petrović, Lisbeth Olsson, Anikó Várnai, Vincent G H Eijsink
Journal: Appl Environ Microbiol
PubMed ID: 34613755
Doi: 10.1128/AEM.01652-21
Products & Services: Codon Optimization   
CST6 protein and peptides inhibit breast cancer bone metastasis by suppressing CTSB activity and osteoclastogenesis
Authors: Xiaoxun Li, Yajun Liang, Cheng Lian, Fangli Peng, Yansen Xiao, Yunfei He, Chengxin Ma, Yuan Wang, Peiyuan Zhang, Yuhan Deng, Yunpeng Su, Cheng Luo, Xiangyin Kong, Qingcheng Yang, Tong Liu, Guohong Hu
Journal: Theranostics
PubMed ID: 34815788
Doi: 10.7150/thno.62187
Products & Services: Catalog Peptides   
Combining an optimized mRNA template with a double purification process allows strong expression of transcribed mRNA
Authors: Sergio Linares-Fernández, Julien Moreno, Elise Lambert, Perrine Mercier-Gouy, Laetitia Vachez, Bernard Verrier, Jean-Yves Exposito
Journal: Mol Ther Nucleic Acids
PubMed ID: 34692232
Doi: 10.1016/j.omtn.2021.10.007
Products & Services: Gene Synthesis   
Epitopes prediction for microcystin-LR by molecular docking
Authors: Yuan Liu, Shu Liu, Chongxin Xu, Manman Lin, Yihang Li, Cheng Shen, Ying Liang, Xing Sun, Donglan Wang, Peng Lü, Xianjin Liu
Journal: Ecotoxicol Environ Saf
PubMed ID: 34717216
Doi: 10.1016/j.ecoenv.2021.112925
Products & Services: Custom Vector Construction   
Genetic, cellular, and structural characterization of the membrane potential-dependent cell-penetrating peptide translocation pore
Authors: Evgeniya Trofimenko, Gianvito Grasso, Mathieu Heulot, Nadja Chevalier, Marco A Deriu, Gilles Dubuis, Yoan Arribat, Marc Serulla, Sebastien Michel, Gil Vantomme, Florine Ory, Linh Chi Dam, Julien Puyal, Francesca Amati, Anita Lüthi, Andrea Danani, Christian Widmann
Journal: Elife
PubMed ID: 34713805
Doi: 10.7554/eLife.69832
Products & Services: Plasmid DNA Preparation   

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